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Volumn 121, Issue 5, 2008, Pages 409-413

Role of TMS5: Staphylococcal multidrug-efflux protein QacA

Author keywords

Exporter; Multidrug resistant; QacA; Staphylococcus aureus; TMS5

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; BACTERIAL PROTEIN; BENZALKONIUM CHLORIDE; CYSTEINE; DEQUALINIUM; ETHIDIUM BROMIDE; MULTIDRUG RESISTANCE PROTEIN; N ETHYLMALEIMIDE; PYRONINE; QACA PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; INDOLE DERIVATIVE; QACA PROTEIN, STAPHYLOCOCCUS AUREUS;

EID: 42449126628     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200803010-00008     Document Type: Article
Times cited : (6)

References (21)
  • 1
    • 0024552014 scopus 로고
    • Physical and biochemical characterization of the qacA gene encoding antiseptic and disinfectant resistance in Staphylococcus aureus
    • Tennent JM, Lyon BR, Midgley M., Jones IG, Purewal AS, Skurray RA. Physical and biochemical characterization of the qacA gene encoding antiseptic and disinfectant resistance in Staphylococcus aureus. J Gen Microbiol 1989; 135: 1-10.
    • (1989) J Gen Microbiol , vol.135 , pp. 1-10
    • Tennent, J.M.1    Lyon, B.R.2    Midgley, M.3    Jones, I.G.4    Purewal, A.S.5    Skurray, R.A.6
  • 2
    • 0025695158 scopus 로고
    • Efflux-mediated antiseptic resistance gene qacA from Staphylococcus aureus common ancestry with tetracycline- and sugar-transport proteins
    • Rouch DA, Cram DS, diBerardino D, Littlejohn TG, Skurray RA. Efflux-mediated antiseptic resistance gene qacA from Staphylococcus aureus common ancestry with tetracycline- and sugar-transport proteins. Mol Microbiol 1990; 4: 2051-2062.
    • (1990) Mol Microbiol , vol.4 , pp. 2051-2062
    • Rouch, D.A.1    Cram, D.S.2    diBerardino, D.3    Littlejohn, T.G.4    Skurray, R.A.5
  • 3
    • 0029872148 scopus 로고    scopus 로고
    • Multidrug resistance pkoteins QacA and QacB from Staphylococcus aureus: Membrane topology and identification of residues involved in substrate specificity
    • Paulsen IT, Brown MH, Littlejohn TG, Mitchell BA, Skurray RA. Multidrug resistance pkoteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity. Proc Natl Acad Sci USA 1996; 93: 3630-3635.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3630-3635
    • Paulsen, I.T.1    Brown, M.H.2    Littlejohn, T.G.3    Mitchell, B.A.4    Skurray, R.A.5
  • 6
    • 0027120761 scopus 로고
    • Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus
    • Littlejohn TG, Paulsen IT, Gillespie MT, Tennent JM, Midgley M. Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus. FEMS Microbiol Let 1992; 95: 259-266.
    • (1992) FEMS Microbiol Let , vol.95 , pp. 259-266
    • Littlejohn, T.G.1    Paulsen, I.T.2    Gillespie, M.T.3    Tennent, J.M.4    Midgley, M.5
  • 7
    • 0033524927 scopus 로고    scopus 로고
    • Bioenergetics of the staphylococcal multidrug export protein QacA: Identification of distinct binding sites for monovalent and divalent cations
    • Mitchell BA, Paulsen IT, Brown MH, Skurray RA. Bioenergetics of the staphylococcal multidrug export protein QacA: identification of distinct binding sites for monovalent and divalent cations. J Biol Chem 1999; 274: 3541-3548.
    • (1999) J Biol Chem , vol.274 , pp. 3541-3548
    • Mitchell, B.A.1    Paulsen, I.T.2    Brown, M.H.3    Skurray, R.A.4
  • 8
    • 33748486707 scopus 로고    scopus 로고
    • Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA
    • Hassan KA, Galea M, Wu J, Mitchell BA, Skurray RA, Brown MH. Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA. FEMS Microbiol Lett 2006; 263: 76-85.
    • (2006) FEMS Microbiol Lett , vol.263 , pp. 76-85
    • Hassan, K.A.1    Galea, M.2    Wu, J.3    Mitchell, B.A.4    Skurray, R.A.5    Brown, M.H.6
  • 9
    • 33644861768 scopus 로고    scopus 로고
    • Role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein QacA
    • Xu Z. O'Rourke BA. SKurray RA. Brown MH. Role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein QacA. J Biol Chem 2006; 281: 792-799.
    • (2006) J Biol Chem , vol.281 , pp. 792-799
    • Xu, Z.1    O'Rourke, B.A.2    SKurray, R.A.3    Brown, M.H.4
  • 10
    • 0021343133 scopus 로고
    • Effect of mutation, electric membrane potential and metabolic inhibitors on the accessibility of nucleic acids to ethidium bromide in Escherichia coli cells
    • Lambert B., and LePecq JB. Effect of mutation, electric membrane potential and metabolic inhibitors on the accessibility of nucleic acids to ethidium bromide in Escherichia coli cells. Biochem. 1984; 23: 166-176.
    • (1984) Biochem , vol.23 , pp. 166-176
    • Lambert, B.1    LePecq, J.B.2
  • 11
    • 0041829085 scopus 로고    scopus 로고
    • The status of drug resistance and ampC gene expression in Enterobacter cloacae
    • Zhou Z, Li L, Yu Y, Ma Y. The status of drug resistance and ampC gene expression in Enterobacter cloacae. Chin Med J 2003; 116: 1244-1247.
    • (2003) Chin Med J , vol.116 , pp. 1244-1247
    • Zhou, Z.1    Li, L.2    Yu, Y.3    Ma, Y.4
  • 12
    • 13644268179 scopus 로고    scopus 로고
    • Relationship between antimicrobial resistance and aminoglycoside-modifying enzyme gene expressions in Acinetobacter baumannii
    • Shi WF, Ran JP, Mi ZH. Relationship between antimicrobial resistance and aminoglycoside-modifying enzyme gene expressions in Acinetobacter baumannii. Chin Med J 2005; 118:141-145.
    • (2005) Chin Med J , vol.118 , pp. 141-145
    • Shi, W.F.1    Ran, J.P.2    Mi, Z.H.3
  • 13
    • 85190572143 scopus 로고    scopus 로고
    • Dougherty DA. Cation-interactions in chemistry and biology: a new review of benzene, Phe, Tyr, and Trp. Science 1996; 271: 163-168.
    • Dougherty DA. Cation-interactions in chemistry and biology: a new review of benzene, Phe, Tyr, and Trp. Science 1996; 271: 163-168.
  • 14
    • 0028097634 scopus 로고
    • Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity
    • Pawagi AB, Wang J, Silverman M, Reithmeier RAF, Deber CM. Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity. J Mol Biol 1994; 235: 554-564.
    • (1994) J Mol Biol , vol.235 , pp. 554-564
    • Pawagi, A.B.1    Wang, J.2    Silverman, M.3    Reithmeier, R.A.F.4    Deber, C.M.5
  • 15
    • 0035782973 scopus 로고    scopus 로고
    • Exploring the structure and function of the P-glycoprotein multidrug transporter using fluorescence spectroscopic tools
    • Sharom FJ, Liu R, Qu Q, Romsicki Y. Exploring the structure and function of the P-glycoprotein multidrug transporter using fluorescence spectroscopic tools. Semin Cell Dev Biol 2001; 12: 257-265.
    • (2001) Semin Cell Dev Biol , vol.12 , pp. 257-265
    • Sharom, F.J.1    Liu, R.2    Qu, Q.3    Romsicki, Y.4
  • 16
    • 0029034869 scopus 로고
    • Molecular characterization of the staphylococcal multidrug resistance export protein QacC
    • Paulsen IT, Brown MH, Dunstan SJ, Sdurray RA. Molecular characterization of the staphylococcal multidrug resistance export protein QacC. J Bacteriol. 1995; 177: 2827-2833.
    • (1995) J Bacteriol , vol.177 , pp. 2827-2833
    • Paulsen, I.T.1    Brown, M.H.2    Dunstan, S.J.3    Sdurray, R.A.4
  • 17
    • 0027371039 scopus 로고
    • Modulatory effects on substrate specificity of independent mutations at the serine939/941 position in predicted transmembrane domain 11 of P-glycoproteins
    • Dhir R, Grizzuti K, Kajiji S, Gros P. Modulatory effects on substrate specificity of independent mutations at the serine939/941 position in predicted transmembrane domain 11 of P-glycoproteins. Biochem 1993; 32: 9492-9499.
    • (1993) Biochem , vol.32 , pp. 9492-9499
    • Dhir, R.1    Grizzuti, K.2    Kajiji, S.3    Gros, P.4
  • 18
    • 0028845359 scopus 로고
    • Identification of residues involved in substrate recognition by a vesicular monoamine transporter
    • Merickel A, Rosandich P, Peter D, Edwards RH. Identification of residues involved in substrate recognition by a vesicular monoamine transporter. J Biol Chem 1995; 270: 25798-25804.
    • (1995) J Biol Chem , vol.270 , pp. 25798-25804
    • Merickel, A.1    Rosandich, P.2    Peter, D.3    Edwards, R.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.