Prospects for the use of differentiation-modulating agents as adjuvant of photodynamic therapy for proliferative dermatoses

Journal of Dermatology

Volumn 35, Issue 4, 2008, Pages 197-205

  Akilov, Oleg E ^a   Kosaka, Sachiko ^a,c   Maytin, Edward V ^b   Hasan, Tayyaba ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Differentiation; Keratinocyte; Photodynamic therapy; Protoporphyrin IX

Indexed keywords

AMINOLEVULINIC ACID; APHIDICOLIN; BEXAROTENE; BROXURIDINE; CALCITRIOL; DIMETHYL SULFOXIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ETRETIN; ETRETINATE; FLUOROURACIL; GAMMA INTERFERON; GRISEOFULVIN; HYDROCORTISONE; HYDROXYUREA; ISOTRETINOIN; KERATINOCYTE GROWTH FACTOR; METHOTREXATE; PHOTOSENSITIZING AGENT; RETINOIC ACID; RETINOL; SOMATOMEDIN; TAZAROTENE; THYMIDINE; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

BASAL CELL CARCINOMA; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HYPERKERATOSIS; IMMUNE SYSTEM; KERATINOCYTE; NONHUMAN; PHOTOCHEMISTRY; PHOTODYNAMIC THERAPY; PSORIASIS; REVIEW; SKIN DISEASE; SKIN LEISHMANIASIS; VERRUCA VULGARIS;

CHEMOTHERAPY, ADJUVANT; DERMATOLOGIC AGENTS; HUMANS; IMMUNOLOGIC FACTORS; PHOTOCHEMOTHERAPY; SKIN DISEASES;

EID: 42449120198     PISSN: 03852407     EISSN: 13468138     Source Type: Journal    
DOI: 10.1111/j.1346-8138.2008.00445.x     Document Type: Review

References (61)

1. Kennedy JC, Pottier RH, Pross DC. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J Photochem Photobiol B 1990 6 : 143 148.
2. Zeitouni NC, Oseroff AR, Shieh S. Photodynamic therapy for nonmelanoma skin cancers. Current review and update. Mol Immunol 2003 39 : 1133 1136.
3. Marmur ES, Schmults CD, Goldberg DJ. A review of laser and photodynamic therapy for the treatment of nonmelanoma skin cancer. Dermatol Surg 2004 30 : 264 271.
4. Szeimies RM. Methyl aminolevulinate-photodynamic therapy for basal cell carcinoma. Dermatol Clin 2007 25 : 89 94.
5. Lehmann P. Methyl aminolaevulinate-photodynamic therapy: a review of clinical trials in the treatment of actinic keratoses and nonmelanoma skin cancer. Br J Dermatol 2007 156 : 793 801.
6. Kalisiak MS, Rao J. Photodynamic therapy for actinic keratoses. Dermatol Clin 2007 25 : 15 23.
7. Morton CA, Whitehurst C, McColl JH, Moore JV, MacKie RM. Photodynamic therapy for large or multiple patches of Bowen disease and basal cell carcinoma. Arch Dermatol 2001 137 : 319 324.
8. Morton CA, Brown SB, Collins S et al. Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group. Br J Dermatol 2002 146 : 552 567.
9. Schleyer V, Radakovic-Fijan S, Karrer S et al. Disappointing results and low tolerability of photodynamic therapy with topical 5-aminolaevulinic acid in psoriasis. A randomized, double-blind phase I/II study. J Eur Acad Dermatol Venereol 2006 20 : 823 828.
10. Radakovic-Fijan S, Blecha-Thalhammer U, Schleyer V et al. Topical aminolaevulinic acid-based photodynamic therapy as a treatment option for psoriasis? Results of a randomized, observer-blinded study. Br J Dermatol 2005 152 : 279 283.
11. Beattie PE, Dawe RS, Ferguson J, Ibbotson SH. Lack of efficacy and tolerability of topical PDT for psoriasis in comparison with narrowband UVB phototherapy. Clin Exp Dermatol 2004 29 : 560 562.
12. Akilov OE, O'Riordan K, Kosaka S, Hasan T. Photodynamic therapy against intracellular pathogens: problems and potentials. Med Laser Appl 2006 21 : 251 260.
13. O'Riordan K, Akilov OE, Hasan T. The potential for photodynamic therapy in the treatment of localized infections. Photodiagnosis Photodynamic Ther 2005 2 : 247 262.
14. Kosaka S, Akilov OE, O'Riordan K, Hasan T. A mechanistic study of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis. J Invest Dermatol 2007 127 : 1546 1549.
15. Akilov OE, Kosaka S, O'Riordan K, Hasan T. Parasiticidal effect of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis is indirect and mediated through the killing of the host cells. Exp Dermatol 2007 16 : 651 660.
16. Akilov OE, Kosaka S, O'Riordan K, Hasan T. Photodynamic therapy for cutaneous leishmaniasis: the effectiveness of topical phenothiaziniums in parasite eradication and Th1 immune response stimulation. Photochem Photobiol Sci 2007 6 : 1067 1075.
17. Ortel B, Chen N, Brissette J, Dotto GP, Maytin E, Hasan T. Differentiation-specific increase in ALA-induced protoporphyrin IX accumulation in primary mouse keratinocytes. Br J Cancer 1998 77 : 1744 1751.
18. Ortel B, Sharlin D, O'Donnell D, Sinha AK, Maytin EV, Hasan T. Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells. Br J Cancer 2002 87 : 1321 1327.
19. Sinha AK, Anand S, Ortel BJ et al. Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells. Br J Cancer 2006 95 : 485 495.
20. Sato N, Moore BW, Keevey S, Drazba JA, Hasan T, Maytin EV. Vitamin D enhances ALA-induced protoporphyrin IX production and photodynamic cell death in 3-D organotypic cultures of keratinocytes. J Invest Dermatol 2007 127 : 925 934.
21. Kosaka S, Kawana S, Zouboulis CC, Hasan T, Ortel B. Targeting of sebocytes by aminolevulinic acid-dependent photosensitization. Photochem Photobiol 2006 82 : 453 457.
22. Hatse S, De Clercq E, Balzarini J. Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation. Biochem Pharmacol 1999 58 : 539 555.
23. Friedman SJ, Skehan P. Morphological differentiation of human choriocarcinoma cells induced by methotrexate. Cancer Res 1979 39 : 1960 1967.
24. Hatse S, Naesens L, De Clercq E, Balzarini J. Potent differentiation- inducing properties of the antiretroviral agent 9-(2-phosphonylmethoxyethyl) adenine (PMEA) in the rat choriocarcinoma (RCHO) tumor cell model. Biochem Pharmacol 1998 56 : 851 859.
25. Bodner AJ, Ting RC, Gallo RC. Induction of differentiation of human promyelocytic leukemia cells (HL-60) by nucleosides and methotrexate. J Natl Cancer Inst 1981 67 : 1025 1030.
26. Ross SA, Jones CS, De Luca LM. Retinoic acid and methotrexate specifically increase PHA-E-lectin binding to a 67-kDa glycoprotein in LA-N-1 human neuroblastoma cells. Int J Cancer 1995 62 : 303 308.
27. Schwartz PM, Barnett SK, Atillasoy ES, Milstone LM. Methotrexate induces differentiation of human keratinocytes. Proc Natl Acad Sci USA 1992 89 : 594 598.
28. Weinstein GD, Jeffes E, McCullough JL. Cytotoxic and immunologic effects of methotrexate in psoriasis. J Invest Dermatol 1990 95 : 49S 52S.
29. Anand S, Sato N, Moore BW, Hasan T, Maytin EV. Transcriptional modulation of coproporphyrinogen oxidase by CCAAT enhancer binding proteins (C/EBPs) and their isoforms: a possible mechanism for enhanced ALA-photodynamic therapy. Proc Am Assoc Cancer Res 2006 47 : 4620.
30. Maytin EV, Anand S, Sato N et al. Nuclear transcription factors: a new approach to enhancing cellular responses to ALA-mediated photodynamic therapy. In : Kessel D, eds. Opt Methods for Tumor Treatment Detect: Mech Techniques Photodynamic Ther XV. Proc SPIE. 2006 6139 : 54 63.
31. Schwartz PM, Barnett SK, Milstone LM. Keratinocytes differentiate in response to inhibitors of deoxyribonucleotide synthesis. J Dermatol Sci 1995 9 : 129 135.
32. Kohno H, Furukawa T, Yoshinaga T, Tokunaga R, Taketani S. Coproporphyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid differentiation. J Biol Chem 1993 268 : 21359 21363.
33. Schoenfeld N, Mamet R, Nordenberg Y, Shafran M, Babushkin T, Malik Z. Protoporphyrin biosynthesis in melanoma B16 cells stimulated by 5-aminolevulinic acid and chemical inducers: characterization of photodynamic inactivation. Int J Cancer 1994 56 : 106 112.
34. Li W, Zhang WJ, Ohnishi K, Yamada I, Ohno R, Hashimoto K. 5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells. J Photochem Photobiol B 2001 60 : 79 86.
35. Nomura J, Yanase S, Tokuda T, Matsumura Y, Sekida M, Tagawa T. Griseofulvin enhances the effect of aminolevulinic acid-based photodynamic therapy in vitro. Photomed Laser Surg 2006 24 : 186 191.
36. Casas A, Fukuda H, Riley P, del CBAM. Enhancement of aminolevulinic acid based photodynamic therapy by adriamycin. Cancer Lett 1997 121 : 105 113.
37. Stender IM, Lock-Andersen J, Wulf HC. Recalcitrant hand and foot warts successfully treated with photodynamic therapy with topical 5-aminolaevulinic acid: a pilot study. Clin Exp Dermatol 1999 24 : 154 159.
38. Stender IM, Na R, Fogh H, Gluud C, Wulf HC. Photodynamic therapy with 5-aminolaevulinic acid or placebo for recalcitrant foot and hand warts: randomised double-blind trial. Lancet 2000 355 : 963 966.
39. Stender IM, Wulf HC. Treatment of recalcitrant verrucae by photodynamic therapy with topical application of delta-aminolaevulinic acid. Clin Exp Dermatol 1996 21 : 390.
40. Stender IM, Wulf HC. Photodynamic therapy of recalcitrant warts with 5-aminolevulinic acid: a retrospective analysis. Acta Derm Venereol 1999 79 : 400 401.
41. Smetana Z, Malik Z, Orenstein A, Mendelson E, Ben-Hur E. Treatment of viral infections with 5-aminolevulinic acid and light. Lasers Surg Med 1997 21 : 351 358.
42. Ammann R, Hunziker T, Braathen LR. Topical photodynamic therapy in verrucae. A pilot study. Dermatology 1995 191 : 346 347.
43. Szeimies RM, Landthaler M, Karrer S. Non-oncologic indications for ALA-PDT. J Dermatolog Treat 2002 13 (Suppl. 1 S13 18.
44. Boehncke WH, Konig K, Kaufmann R, Scheffold W, Prummer O, Sterry W. Photodynamic therapy in psoriasis: suppression of cytokine production in vitro and recording of fluorescence modification during treatment in vivo. Arch Dermatol Res 1994 286 : 300 303.
45. Kim JY, Kang HY, Lee ES, Kim YC. Topical 5- aminolaevulinic acid photodynamic therapy for intractable palmoplantar psoriasis. J Dermatol 2007 34 : 37 40.
46. Yim YC, Lee ES, Chung PS, Rhee CK. Recalcitrant palmoplantar pustular psoriasis successfully treated with topical 5-aminolaevulinic acid photodynamic therapy. Clin Exp Dermatol 2005 30 : 723 724.
47. Pres H, Meffert H, Sonnichsen N. [Photodynamic therapy of psoriasis palmaris et plantaris using a topically applied hematoporphyrin derivative and visible light]. Dermatol Monatsschr 1989 175 : 745 750.
48. Braathen LR, Szeimies RM, Basset-Seguin N et al. Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005. J Am Acad Dermatol 2007 56 : 125 143.
49. Smits T, Kleinpenning MM, van Erp PE, van de Kerkhof PC, Gerritsen MJ. A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis. Br J Dermatol 2006 155 : 429 436.
50. Fransson J, Ros AM. Clinical and immunohistochemical evaluation of psoriatic plaques treated with topical 5-aminolaevulinic acid photodynamic therapy. Photodermatol Photoimmunol Photomed 2005 21 : 326 332.
51. Kleinpenning MM, Smits T, Ewalds E, van Erp PE, van de Kerkhof PC, Gerritsen MJ. Heterogeneity of fluorescence in psoriasis after application of 5-aminolaevulinic acid: an immunohistochemical study. Br J Dermatol 2006 155 : 539 545.
52. Babilas P, Karrer S, Sidoroff A, Landthaler M, Szeimies RM. Photodynamic therapy in dermatology - an update. Photodermatol Photoimmunol Photomed 2005 21 : 142 149.
53. Morton CA. Methyl aminolevulinate (Metvix) photodynamic therapy - practical pearls. J Dermatolog Treat 2003 14 (Suppl. 3 23 26.
54. Regnier M, Darmon M. 1,25-Dihydroxyvitamin D3 stimulates specifically the last steps of epidermal differentiation of cultured human keratinocytes. Differentiation 1991 47 : 173 188.
55. Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature 2007 445 : 866 873.
56. Bissonnette R, Tremblay JF, Juzenas P, Boushira M, Lui H. Systemic photodynamic therapy with aminolevulinic acid induces apoptosis in lesional T lymphocytes of psoriatic plaques. J Invest Dermatol 2002 119 : 77 83.
57. Evans S, Matthews W, Perry R, Fraker D, Norton J, Pass HI. Effect of photodynamic therapy on tumor necrosis factor production by murine macrophages. J Natl Cancer Inst 1990 82 : 34 39.
58. Gollnick SO, Evans SS, Baumann H et al. Role of cytokines in photodynamic therapy-induced local and systemic inflammation. Br J Cancer 2003 88 : 1772 1779.
59. Yamamoto N, Homma S, Sery TW, Donoso LA, Hoober JK. Photodynamic immunopotentiation: in vitro activation of macrophages by treatment of mouse peritoneal cells with haematoporphyrin derivative and light. Eur J Cancer 1991 27 : 467 471.
60. Ribeiro RC, Kushner PJ, Baxter JD. The nuclear hormone receptor gene superfamily. Annu Rev Med 1995 46 : 443 453.
61. Lu NZ, Wardell SE, Burnstein KL et al. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacol Rev 2006 58 : 782 797.