A hydrophilic cation-binding protein of Arabidopsis thaliana, AtPCaP1, is localized to plasma membrane via N-myristoylation and interacts with calmodulin and the phosphatidylinositol phosphates PtdIns(3,4,5)P3 and PtdIns(3,5)P2

FEBS Journal

Volumn 275, Issue 9, 2008, Pages 2267-2282

  Nagasaki, Nahoko ^a   Tomioka, Rie ^a   Maeshima, Masayoshi ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Arabidopsis; Calcium; Myristoylation; Phosphatidylinositol phosphate; Plasma membrane

Indexed keywords

ARABIDOPSIS PROTEIN; CALCIUM ION; CALMODULIN; GLYCINE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,5 BISPHOSPHATE; POLYPHOSPHOINOSITIDE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARABIDOPSIS; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; IMMUNOBLOTTING; MUTATIONAL ANALYSIS; MYRISTYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; QUANTITATIVE ANALYSIS;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARABIDOPSIS PROTEINS; CALCIUM-BINDING PROTEINS; CALMODULIN; CARRIER PROTEINS; CATIONS; CELL MEMBRANE; CONSERVED SEQUENCE; GREEN FLUORESCENT PROTEINS; MOLECULAR SEQUENCE DATA; MYRISTIC ACID; PHOSPHATIDYLINOSITOL PHOSPHATES; PLANT ROOTS; PLANT SHOOTS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS;

ARABIDOPSIS; ARABIDOPSIS THALIANA;

EID: 42449118441     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06379.x     Document Type: Article

References (47)

1. Resh MD (1994) Myristoylation and palmitoylation of Src family members: the fats of the matter. Cell 76, 411 413.
2. Cadwallader KA, Paterson H, Macdonald SG Hancock JF (1994) N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization. Mol Cell Biol 14, 4722 4730.
3. Boutin JA (1997) Myristoylation Cell Signal 9, 15 35.
4. Boisson B, Giglione C Meinnel T (2003) Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. J Biol Chem 278, 43418 43429.
5. Petsko GA Ringe D (2004) In Protein Structure and Function. 3-19 Protein targeting by lipid modification, pp. 124 125. New Science Press Limited, London.
6. Murase K, Shiba S, Iwano M, Che FS, Watanabe M, Isogai A Takayama S (2004) A membrane-anchored protein kinase involved in Brassica self-incompatibility signaling. Science 303, 1516 1519.
7. Thompson GA Jr. Okuyama H (2000) Lipid-linked proteins of plants. Prog Lipid Res 39, 19 39.
8. 2 and proteins: interactions, organization, and information flow. Annu Rev Biophys Biomol Struct 31, 151 175.
9. Meijer HJG Munnik T (2003) Phospholipid-based signaling in plants. Annu Rev Plant Biol 54, 265 306.
10. 2 is required for delivery of endocytic cargo into the multivesicular body. Traffic 4, 479 490.
11. Roth MG (2004) Phosphoinositides in constitutive membrane traffic. Physiol Rev 84, 699 730.
12. Ide Y, Nagasaki N, Tomioka R, Suito M, Kamiya T Maeshima M (2007) Molecular properties of a novel, hydrophilic cation-binding protein associated with the plasma membrane. J Exp Bot 58, 1173 1183.
13. Logan DC, Domergue O, Teyssendier de la Serve B Rossignol M (1997) A new family of plasma membrane polypeptides differentially regulated during plant development. Biochem Mol Biol Int 43, 1051 1062.
14. Ishitani M, Liua J, Halftera U, Kima C-S, Shia W Zhua JK (2000) SOS3 function in plant salt tolerance requires N-myristoylation and calcium binding. Plant Cell 12, 1667 1678.
15. O'Callaghan DW, Haynes LP Burgoyne RD (2005) High-affinity interaction of the N-terminal myristoylation motif of the neuronal calcium sensor protein hippocalcin with phosphatidylinositol 4,5-bisphosphate. Biochem J 391, 231 238.
16. Kaadige MR Ayer DE (2006) The polybasic region that follows the plant homeodomain zinc finger 1 of Pf1 is necessary and sufficient for specific phosphoinositide binding. J Biol Chem 281, 28831 28836.
17. Sanders D, Pelloux J, Brownlee C Harper JF (2002) Calcium at the crossroads of signaling. Plant Cell 14, S401 S417.
18. Sze H, Liang F, Hwang I, Curran AC Harper JF (2000) Diversity and regulation of plant Ca21 pumps: insights from expression in yeast. Annu Rev Plant Phys Plant Mol Biol 51, 433 462.
19. Farazi TA, Waksman G Gordon JI (2001) The biology and enzymology of protein N-myristoylation. J Biol Chem 276, 39501 39504.
20. Giglione C, Serero A, Pierre M, Boisson B Meinnel T (2000) Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms. EMBO J 19, 5916 5929.
21. Ross S, Giglione G, Pierre M, Espagne C Meinnel T (2005) Functional and developmental impact of cytosolic protein N-terminal methionine excision in Arabidopsis. Plant Physiol 137, 623 637.
22. Ellard-Ivey M, Hopkins RB, White TJ Lomax TL (1999) Cloning, expression and N-terminal myristoylation of CpCPK1, a calcium-dependent protein kinase from zucchini (Cucurbita prop L.). Plant Mol Biol 39, 199 208.
23. Lu SX Hrabak E (2002) An Arabidopsis calcium-dependent protein kinase is associated with the endoplasmic reticulum. Plant Physiol 128, 1008 1021.
24. Rutschmann F, Stalder U, Piotrowski M, Oecking C Schaller A (2002) LeCPK1, a calcium-dependent protein kinase from tomato. Plasma membrane targeting and biochemical characterization. Plant Physiol 129, 156 168.
25. Martin ML Busconi L (2000) Membrane localization of a rice calcium-dependent protein kinase (CDPK) is mediated by myristoylation and palmitoylation. Plant J 24, 429 435.
26. Ueda T, Yamaguchi M, Uchimiya H Nakano A (2001) Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana. EMBO J 20, 4730 4741.
27. Stevenson JM, Perera IY, Heilmann I, Persson S Boss WF (2000) Inositol signaling and plant growth. Trends Plant Sci 5, 252 258.
28. Jung J-Y, Kim Y-W, Kwak JM, Hwang J-U, Young J, Schroeder JI, Hwang I Lee Y (2002) Phosphatidylinositol 3- and 4-phosphate are required for normal stomatal movements. Plant Cell 14, 2399 2414.
29. Varnai P, Lin X, Lee SB, Tuymetova G, Bondeva T, Spat A, Rhee SG, Hajnoczky G Balla T (2002) Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130. J Biol Chem 277, 27412 27422.
30. Yu JW Lemmon MA (2001) All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate. J Biol Chem 276, 44179 44184.
31. Misra S, Miller GJ Hurley JH (2001) Recognizing phosphatidylinositol 3-phosphate. Cell 107, 559 562.
32. Sbrissa D, Ikonomov OC Shisheva A (2002) Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve: binding specificity and role in PIKfyve endomembrane localization. J Biol Chem 277, 6073 6079.
33. Simonsen A, Birkeland HCG, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A Stenmark H (2004) Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J Cell Sci 117, 4239 4251.
34. Santagata S, Boggon TJ, Baird CL, Gomez CA, Zhao J, Shan WS, Myszka DG Shapiro L (2001) G-protein signaling through tubby proteins. Science 292, 2041 2050.
35. Rosenhouse-Dantsker A Logothetis DE (2007) Molecular characteristics of phosphoinositide binding. Pflugers Arch - Eur J Physiol 455, 45 53.
36. Mueller-Roeber B Pical C (2002) Inositol phospholipids metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipids kinase and phosphoinositide-specific phospholipase C. Plant Physiol 130, 22 46.
37. Dove SK, Cooke FT, Douglas MR, Sayers LG, Parker PJ Michell RH (1997) Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390, 187 192.
38. Meijer HJG, Berrie CP, Iurisci C, Divecha N, Musgrave A Munnik T (2001) Identification of a new polyphosphoinositide in plants, phosphatidylinositol 5-monoposphate (PtdIns5P), and its accumulation upon osmotic stress. Biochem J 360, 491 498.
39. Meijer HJG, Divecha N, van den Ende H, Musgrave A Munnik T (1999) Hyperosmotic stress induces rapid synthesis of phosphatidyl-d-inositol 3,5-bisphosphate in plant cells. Planta 208, 294 298.
40. 2+/calmodulin. EMBO J 23, 712 718.
41. 3 in cells. J Histochem Cytochem 50, 697 708.
42. Kobae Y, Sekino T, Yoshioka H, Nakagawa T, Martinoia E Maeshima M (2006) Loss of AtPDR8, a plasma membrane ABC transporter of Arabidopsis thaliana, causes hypersensitive cell death upon pathogen infection. Plant Cell Physiol 47, 309 318.
43. Ishikawa F, Suga S, Uemura T, Sato MH Maeshima M (2005) Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana. FEBS Lett 579, 5814 5820.
44. +-ATPase interaction. Plant Cell Physiol 45, 1202 1210.
45. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ Klenk DC (1985) Measurement of protein using bicinchoninic acid. Anal Biochem 150, 76 85.
46. Kirsch RD Joly E (1998) An improved PCR-mutagenesis strategy for two-site mutagenesis or sequence swapping between related genes. Nucleic Acids Res 26, 1848 1850.
47. Matsubara M, Titani K, Taniguchi H Hayashi N (2003) Direct involvement of protein myristoylation in myristoylated alanine-rich C kinase substrate (MARCKS)-calmodulin interaction. J Biol Chem 278, 48898 48902.