Ptdlns(3,5)P2 is required for delivery of endocytic cargo into the multivesicular body

Traffic

Volumn 4, Issue 7, 2003, Pages 479-490

  Shaw, Jonathan D ^a   Hama, Hiroko ^b   Sohrabi, Farrokh ^a   DeWald, Daryll B ^b   Wendland, Beverly ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UTAH STATE UNIVERSITY   (United States)

Author keywords

Endocytosis; Fab1; Phosphoinositides; Sorting; Ste3; Ubiquitin; Vacuole; Yeast

Indexed keywords

MEMBRANE PROTEIN; MUTANT PROTEIN; PHOSPHOTRANSFERASE; TRIPHOSPHOINOSITIDE; FAB1 PROTEIN, S CEREVISIAE; FLUORESCENT DYE; G PROTEIN COUPLED RECEPTOR; MATING HORMONE ALPHA FACTOR RECEPTOR; PHEROMONE RECEPTOR; PHOSPHATIDYLINOSITOL 3,5 DIPHOSPHATE; PHOSPHATIDYLINOSITOL 3,5-DIPHOSPHATE; POLYPHOSPHOINOSITIDE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE; STE3 PROTEIN, S CEREVISIAE;

ALLELE; ARTICLE; CATALYSIS; CELL MEMBRANE; CELL TRANSPORT; CELL VACUOLE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; INTERNALIZATION; LYSOSOME; LYSOSOME MEMBRANE; MEMBRANE FUSION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TARGETING; AMINO ACID SEQUENCE; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; ENDOCYTOSIS; ENDOSOMES; FLUORESCENT DYES; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POINT MUTATION; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, MATING FACTOR; RECEPTORS, PHEROMONE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; VACUOLES;

EID: 0038758990     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2003.t01-1-00106.x     Document Type: Article

References (39)

1. Stahl PD, Barbieri MA. Multivesicular bodies and multivesicular endosomes: the 'ins and outs' of endosomal traffic. Sci STKE 2002;141: PE32.
2. Pelham H. Insights from yeast endosomes. Curr Opin Cell Biol 2002;14:454-462.
3. Wendland B, Emr SD, Riezman H. Protein traffic in the yeast endocytic and vacuolar protein sorting pathways. Curr Opin Cell Biol 1998;10:513-522.
4. Geli MI, Riezman H. Endocytic internalization in yeast and animal cells: similar and different. J Cell Sci 1998;111:1031-1037.
5. Chen L, Davis NG. Ubiquitin-independent entry into the yeast recycling pathway. Traffic 2002;3:110-123.
6. Katzmann DJ, Babst M, Emr SD. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 2001;106:145-155.
7. Odorizzi G, Babst M, Emr SD. Fab1p Ptdlns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell 1998;95:847-858.
8. Gary JD, Wurmser AE, Bonangelino CJ, Weisman LS, Emr SD. Fab1p is essential for Ptdlns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis. J Cell Biol 1998;143:65-79.
9. Yamamoto A, DeWald DB, Boronenkov IV, Anderson RA, Emr SD, Koshland D. Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol Biol Cell 1995;6:525-539.
10. Ikonomov OC, Sbrissa D, Shisheva A. Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve. J Biol Chem 2001;276:26141-26147.
11. Fernandez-Borja M, Wubbolts R, Calafat J, Janssen H, Divecha N, Dusseljee S, Neefjes J. Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity. Curr Biol 1999;9:55-58.
12. Bryant NJ, Piper RC, Weisman LS, Stevens TH. Retrograde traffic out of the yeast vacuole to the TGN occurs via the prevacuolar/endosomal compartment. J Cell Biol 1998;142:651-663.
13. Wendland B, McCaffery JM, Xiao Q, Emr SD. A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15. J Cell Biol 1996;135:1485-1500.
14. Vida T, Wendland B. Flow cytometry/cell sorting for isolating membrane trafficking mutants in yeast. Meth Enzymol 2002;351:623-631.
15. Dove SK, Cooke FT, Douglas MR, Sayers LG, Parker PJ, Michell RH. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 1997;390:187-192.
16. Cooke FT, Dove SK, McEwen RK, Painter G, Holmes AB, Hall MN, Michell RH, Parker PJ. The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Curr Biol 1998;8:1219-1222.
17. Urbanowski JL, Piper RC. Ubiquitin sorts proteins into the intralumenal degradative compartment of the late-endosome/vacuole. Traffic 2001;2:622-630.
18. Wang YX, Zhao H, Harding TM, Gomes de Mesquita DS, Woldringh CL, Klionsky DJ, Munn AL, Weisman LS. Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly. Mol Biol Cell 1996;7:1375-1389.
19. Kunz J, Wilson MP, Kisseleva M, Hurley JH, Majerus PW, Anderson RA. The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol Cell 2000;5:1-11.
20. Rao VD, Misra S, Boronenkov IV, Anderson RA, Hurley JH. Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. Cell 1998;94:829-839.
21. Hanks SK, Hunter T. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J 1995;9:576-596.
22. Gary JD, Sato TK, Stefan CJ, Bonangelino CJ, Weisman LS, Emr SD. Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell 2002;13:1238-1251.
23. Bonangelino CJ, Nau JJ, Duex JE, Brinkman M, Wurmser AE, Gary JD, Emr SD, Weisman LS. Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 2002;156:1015-1028.
24. Dove SK, McEwen RK, Mayes A, Hughes DC, Beggs JD, Michell RH. Vac14 controls Ptdlns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body. Curr Biol 2002;12: 885-893.
25. Kawasaki-Nishi S, Nishi T, Forgac M. Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociation. J Biol Chem 2001;276: 17941-17948.
26. Kane PM, Parra KJ. Assembly and regulation of the yeast vacuolar H (+) -ATPase. J Exp Biol 2000;203:81-87.
27. Perzov N, Padler-Karavani V, Nelson H, Nelson N. Characterization of yeast V-ATPase mutants lacking Vph1p or Stv1p and the effect on endocytosis. J Exp Biol 2002;205:1209-1219.
28. Babst M, Katzmann DJ, Snyder WB, Wendland B, Emr SD. Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev Cell 2002;3:283-289.
29. Babst M, Katzmann DJ, Estepa-Sabal EJ, Meerloo T, Emr SD. Escrt III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev Cell 2002;3:271-282.
30. Roth AF, Sullivan DM, Davis NG. A large PEST-like sequence directs the ubiquitination, endocytosis, and vacuolar degradation of the yeast a-factor receptor. J Cell Biol 1998;142:949-961.
31. Reggiori F, Pelham HR. Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting. EMBO J 2001;20: 5176-5186.
32. Reggiori F, Pelham HR. A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies. Nat Cell Biol 2002;4:117-123.
33. Amerik AY, Nowak J, Swaminathan S, Hochstrasser M. The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 2000;11: 3365-3380.
34. Reggiori F, Black MW, Pelham HR. Polar transmembrane domains target proteins to the interior of the yeast vacuole. Mol Biol Cell 2000;11:3737-3749.
35. Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J 2000;351: 19-31.
36. DeWald D. Phosphoinositide signaling: vac to the future in fab1 kinase regulation. Curr Biol 2002;12:R491.
37. Hama H, Takemoto JY, DeWald DB. Analysis of phosphoinositides in protein trafficking. Methods 2000;20:465-473.
38. Stock SD, Hama H, DeWald DB, Takemoto JY. SEC14-dependent secretion in Saccharomyces cerevisiae. Nondependence on sphingolipid synthesis-coupled diacylglycerol production. J Biol Chem 1999;274: 12979-12983.
39. Rieder SE, Banta LM, Kohrer K, McCaffery JM, Emr SD. Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol Biol Cell 1996;7:985-999.