Angiotensin II activates myostatin expression in cultured rat neonatal cardiomyocytes via p38 MAP kinase and myocyte enhance factor 2 pathway

Journal of Endocrinology

Volumn 197, Issue 1, 2008, Pages 85-93

  Wang, Bao Wei ^a,b   Chang, Hang ^a   Kuan, Peiliang ^a   Shyu, Kou Gi ^a,c  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN II; LOSARTAN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOCYTE ENHANCER FACTOR 2; MYOSTATIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HEART CELL CULTURE; HORMONAL REGULATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; RNA INTERFERENCE;

ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; CARDIOMEGALY; MADS DOMAIN PROTEINS; MAP KINASE SIGNALING SYSTEM; MYOCYTES, CARDIAC; MYOGENIC REGULATORY FACTORS; MYOSTATIN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; PROTEIN BIOSYNTHESIS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 42449100435     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-07-0596     Document Type: Article

References (34)

1. Aikawa R, Nagai T, Kudoh S, Zou Y, Tanaka M, Tamura M, Kazawa H, Takano H, Nagai R & Komuro, I 2002 Integrins play a critical role in mechanical stress-induced p38 MAPK activation. Hypertension 39 233-238.
2. Akazawa H & Komuro I 2003 Roles of cardiac transcription factors in cardiac hypertrophy. Circulation Research 92 1079-1088.
3. Anker SD, Steinborn W & Strassbourg S 2004 Cardiac cachexia. Annals of Medicine 36 518-529.
4. Arraza JN, Reisz-Porszasz S, Dow JS, Kloner RA, Tsao J, Bhasin S & Gonzaler-Cadavid NF 2007 Alteration in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse. Journal of Endocrinology 194 63-76.
5. Brink M, Chrast J, Price R, Mitch WE & Delafontaine P 1999 Angiotensin II stimulates gene expression of cardiac insulin-like growth factor 1 and its receptor through effects oil blood pressure and food intake. Hypertension 34 1053-1059.
6. Cohn RD, Liang HY, Shetty R, Abraham T & Wanger KR 2007 Myostatin does not regulate cardiac hypertrophy or fibrosis. Neuromuscular Disorders 17 290-296.
7. Cook SA, Matsui T, Li L & Bosenzweig A 2002 Transcriptional effects of chronic Akt activation in the heart. Journal of Biological Chemistry 277 22528-22533.
8. Delafontaine P, Song YH & Li Y 2004 Expression, regulation, and function of IGF-1 IGF-1R, and IGF-1 binding proteins in blood vessels. Arteriosclerosis, Thrombosis, and Vascular Biology 24 435-444.
9. Donohue TJ, Dworkin LD, Lango MN, Fliegner K, Lango RP, Benetein JA, Slater WR & Catanese VM 1994 Induction of myocardial insulin-like growth factor-1 gene expression in left ventricular hypertrophy. Circulation 89 799-809.
10. Gaussin V & Depre C 2005 Myostatin, the cardiac chalone of insulin-like growth factor-1. Cardiovascular Research 68 347-349.
11. Lee SJ & McPherron AC 2001 Regulation of myostatin activity and muscle growth. PNAS 98 9306-9311.
12. Leri A, Liu Y, Wang X, Kajstura J, Malhotra A, Meggs, LG & Anversa P 1999 Overexpression of insulin-like growth factor-1 attenuates the myocyte rennin-angiotensin system in transgenic mice. Circulation Research 84 752-762.
13. Liang Q & Molkentin JD 2003 Redefining the roles of p38 and JNK signaling in cardiac hypertrophy: dichotomy between cultured myocytes and animal models. Journal of Molecular and Cellular Cardiolcgy 35 1385-1394.
14. Loennechen JP, Stoylen A, Beisvang V, Wisloff U & Ellingsen O 2001 Regional expression of endothelin-1, ANP, IGF-1, and LV wall stress in the infarcted rat heart. American Journal of Physiology 280 H2902-H2910.
15. McKoy G, Bicknell KA, Patel K & Brooks G 2007 Developmental expression of myostatin in cardiomyocytes and its effect on fetal and neonatal rat cardiomyocyte proliferation. Cardiovascular Research 74 304-312.
16. McPherron AC, Lawler AM & Lee SJ 1997 Regulation of skeletal muscle mass in mice by a new TGF-β superfamily member. Nature 387 83-90.
17. Morissetre MR, Cook SA, Foo SY, McKoy G, Ashida N, Novikov M, Scherrer-Crosbie M, Li L, Matsui T, Brooks G et al. 2006 Myostatin regulates cardiomyocytes growth through modulation of Akt signaling. Circulation Research 99 15-24.
18. Palmieri EA, Benincasa G, Di Rella F, Casaburi C, Monti MG, De Simone G, Chiariotri L, Palombini L, Bruni CB, Sacca L et al. 2001 Differential expression of TNF-α, IL-6, and IGF-1 by graded mechanical stress in normal rat myocardium. American Journal of Physiology 282 H926-H934.
19. Sadoshima JI, Xu Y, Slayter LIS & lzumo S 1993 Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 75 977-984.
20. Schnee JM & Hsueh WA 2000 Angiotensin II adhesion, and cardiac fibrosis. Cardiovascular Research 46 264-268.
21. Sharma M, Kambadur R, Matthews KG, Somers WG, Delvin GP, Conaglen JV, Fowke FJ & Bass JJ 1999 Myostatin, a transforming growth factor-β superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct. Journal of Cellular Physiology 180 1-9.
22. Shyu KG, Chen CC, Wang BW & Kuan P 2001 Angionensin II receptor antagonist blocks the expression of connexin43 induced by cyclical mechanical stretch in cultured neonatal rat cardiac myocytes. Journal of Molecular and Cellular Cardiology 33 691-698.
23. Shyu KG, Wang BW, Yang YH, Tsai SC, Lin S & Lee CC 2004 Amphetamine activates colmexin43 gene expression in cultured neonatal rat cardiomyocytes through JNK and AP-1 pathway. Cardiovascular Research 63 98-108.
24. Shyu KG, Ko WH, Yang WS, Wang BW & Kuan P 2005 Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes. Cardiovascular Research 68 405-414.
25. Song YH, Li Y, Du J, Mitch WE, Rosenthal N & Delafontaine P 2005 Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting. Journal of Clinical Investigation 115 451-458.
26. Spiller MP, Kambadur R, Jeanplong F, Thomas M, Martyn JK, Bass JJ & Sharma M 2002 The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyOD. Molecular and Cellular Biology 22 7066-7082.
27. Thies RS, Chen T, Davies MV, Tomkinson KN, Pearson AA, Shakey QA & Wolfinan NM 2001 GDF-8 propepride binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding. Growth Factors 18 251-259.
28. Torsoni AS, Constancio SS, Nadruz W, Hanks SK & Franchini KG 2003 Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes. Circulation Research 93 140-147.
29. Wang L, Ma W, Markovich R, Lee WL & Wang PH 1998 Insulin-like growth factor 1 modulates induction of apoptotic signaling in H9C2 cardiac muscle cells. Endocrinology 139 354-1360.
30. Yang W, Zhang Y, Li Y, Wu Z & Zhu D 2007 Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3β pathway and is antagonized by insulin-like growth factor-1. Journal of Biological Chemistry 282 3799-3808.
31. Zetser A, Gredinger E & Bengal E 1999 p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Journal of Biological Chemistry 274 5193-5200.
32. Zhao M, New L, Kravchenko VV, Kato Y, Grain H, di Padova F, Olson EN, Ulevitch RJ & Han J 1999 Regulation of the MEF2 family of transcription factors by p38. Molecular and Cellular Biology 19 21-30.
33. Zimmers TA, Davies MV, Koniaris LC, Haynes P, Esquela AF, Tomkinson KN, McPherron AC, Wolfman NM & Lee SJ 2002 Induction of cachexia in mice by systemically administered myostatin. Science 296 1486-1488.
34. Zou Y, Akazawa H, Qin Y, Sano M, Takano H, Minamino T, Makita N, Iwanaga K, Zhu W, Kudoh S et al. 2004 Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nature Cell Biology 6 499-506.