Identification of cyclic adenosine 3′,5′-monophosphate response element modulator as an activator of the human sodium/iodide symporter upstream enhancer

Endocrinology

Volumn 149, Issue 5, 2008, Pages 2592-2606

  Fenton, Mike S ^a   Marion, Kenneth M ^b   Hershman, Jerome M ^b  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; COTRANSPORTER; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; MESSENGER RNA; SODIUM IODIDE; THYROTROPIN; TRANSCRIPTION FACTOR PAX8;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; SIGNAL TRANSDUCTION; THYROID CANCER; WESTERN BLOTTING;

ANIMALS; CARCINOMA, PAPILLARY; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT MODULATOR; ENHANCER ELEMENTS (GENETICS); FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PAIRED BOX TRANSCRIPTION FACTORS; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; RATS; SYMPORTERS; THYROID NEOPLASMS; TRANS-ACTIVATION (GENETICS);

EID: 42449098970     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-1390     Document Type: Article

References (41)

1. Klein M, Aubert V, Weryha G, Leclere J 1996 [Classification and epidemiology of thyroid tumors]. Rev Prat 46:2288-2295 (French)
2. Hundahl SA, Cady B, Cunningham MP, Mazzaferri E, McKee RF, Rosai J, Shah JP, Fremgen AM, Stewart AK, Holzer S 2000 Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the united states during 1996. U.S. and German Thyroid Cancer Study Group. An American College of Surgeons Commission on Cancer Patient Care Evaluation study. Cancer 89:202-217
3. Shen DH, Kloos RT, Mazzaferri EL, Jhian SM 2001 Sodium iodide symporter in health and disease. Thyroid 11:415-425
4. Kogai T, Curcio F, Hyman S, Cornford EM, Brent GA, Hershman JM 2000 Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression. J Endocrinol 167:125-135
5. Saito T, Endo T, Kawaguchi A, Ikeda M, Nakazato M, Kogai T, Onaya T 1997 Increased expression of the Na+/I- symporter in cultured human thyroid cells exposed to thyrotropin and in Graves' thyroid tissue. J Clin Endocrinol Metab 82:3331-3336
6. Kogai T, Endo T, Saito T, Miyazaki A, Kawaguchi A, Onaya T 1997 Regulation by thyroid-stimulating hormone of sodium/iodide symporter gene expression and protein levels in FRTL-5 cells. Endocrinology 138:2227-2232
7. Weiss SJ, Philp NJ, Ambesi-Impiombato FS, Grollman EF 1984 Thyrotropin-stimulated iodide transport mediated by adenosine 3′,5′-monophosphate and dependent on protein synthesis. Endocrinology 114:1099-1107
8. Taki K, Kogai T, Kanamoto Y, Hershman JM, Brent GA 2002 A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3′,5′-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol Endocrinol 16:2266-2282
9. Venkateswaran A, Marsee DK, Green SH, Jhiang SM 2004 Forskolin, 8-Br-3′,5′-cyclic adenosine 5′-monophosphate, and catalytic protein kinase A expression in the nucleus increase radioiodide uptake and sodium/iodide symporter protein levels in RET/PTC1-expressing cells. J Clin Endocrinol Metab 89:6168-6172
10. Dulgeroff AJ, Hershman JM 1994 Medical therapy for differentiated thyroid carcinoma. Endocr Rev 15:500-515
11. Ryu KY, Tong Q, Jhiang SM 1998 Promoter characterization of the human Na+/I- symporter. J Clin Endocrinol Metab 83:3247-3251
12. Tong Q, Ryu KY, Jhiang SM 1997 Promoter characterization of the rat Na+/I- symporter gene. Biochem Biophys Res Commun 239:34-41
13. Endo T, Kaneshige M, Nakazato M, Ohmori M, Harii N, Onaya T 1997 Thyroid transcription factor-1 activates the promoter activity of rat thyroid Na+/I- symporter gene. Mol Endocrinol 11:1747-1755
14. Ohmori M, Endo T, Harii N, Onaya T 1998 A novel thyroid transcription factor is essential for thyrotropin-induced up-regulation of Na+/I- symporter gene expression. Mol Endocrinol 12:727-736
15. Ohno M, Zannini M, Levy O, Carrasco N, di Lauro R 1999 The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. Mol Cell Biol 19:2051-2060
16. Chun JT, Di Dato V, D'Andrea B, Zannini M, Di Lauro R 2004 The CRE-like element inside the 5′-upstream region of the rat sodium/iodide symporter gene interacts with diverse classes of b-Zip molecules that regulate transcriptional activities through strong synergy with Pax-8. Mol Endocrinol 18:2817-2829
17. Jhiang SM 2000 Regulation of sodium/iodide symporter. Rev Endocr Metab Disord 1:205-215
18. Fabbro D, Pellizzari L, Mercuri F, Tell G, Damante G 1998 Pax-8 protein levels regulate thyroglobulin gene expression. J Mol Endocrinol 21:347-354
19. Lalli E, Sassone-Corsi P 1994 Signal transduction and gene regulation: the nuclear response to cAMP. J Biol Chem 269:17359-17362
20. Rosenberg D, Groussin L, Jullian E, Perlemoine K, Bertagna X, Bertherat J 2002 Role of the PKA-regulated transcription factor CREB in development and tumorigenesis of endocrine tissues. Ann NY Acad Sci 968:65-74
21. Yamamoto KK, Gonzalez GA, Biggs 3rd WH, Montminy MR 1988 Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature 334:494-498
22. Gonzalez GA, Montminy MR 1989 Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680
23. Meyer TE, Habener JF 1992 Cyclic AMP response element binding protein CREB and modulator protein CREM are products of distinct genes. Nucleic Acids Res 20:6106
24. Hai T, Curran T 1991 Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc Natl Acad Sci USA 88:3720-3724
25. De Cesare D, Fimia GM, Sassone-Corsi P 1999 Signaling routes to CREM and CREB: plasticity in transcriptional activation. Trends Biochem Sci 24:281-285
26. Ambesi-Impiombato FS, Parks LA, Coon HG 1980 Culture of hormone-dependent functional epithelial cells from rat thyroids. Proc Natl Acad Sci USA 77:3455-3459
27. Ohta K, Pang XP, Berg L, Hershman JM 1996 Antitumor actions of cytokines on new human papillary thyroid carcinoma cell lines. J Clin Endocrinol Metab 81:2607-2612
28. Ohta K, Pang XP, Berg L, Hershman JM 1997 Growth inhibition of new human thyroid carcinoma cell lines by activation of adenylate cyclase through the β-adrenergic receptor. J Clin Endocrinol Metab 82:2633-2638
29. Tyson-Capper AJ, Bailey J, Krainer AR, Robson SC, Europe-Finner GN 2005 The switch in alternative splicing of cyclic AMP-response element modulator protein CREMτ2α(activator) to CREMα (repressor) in human myometrial cells is mediated by SRp40. J Biol Chem 280:34521-34529
30. Kogai T, Hershman JM, Motomura K, Endo T, Onaya T, Brent GA 2001 Differential regulation of the human sodium/iodide symporter gene promoter in papillary thyroid carcinoma cell lines and normal thyroid cells. Endocrinology 142:3369-3379
31. Ohmori M, Harii N, Endo T, Onaya T 1999 Tumor necrosis factor-α regulation of thyroid transcription factor-1 and Pax-8 in rat thyroid FRTL-5 cells. Endocrinology 140:4651-4658
32. Fenton MS, Gralla JD 2001 Function of the bacterial TATAAT-10 element as single-stranded DNA during RNA polymerase isomerization. Proc Natl Acad Sci USA 98:9020-9025
33. Delmas V, Laoide BM, Masquilier D, de Groot RP, Foulkes NS, Sassone-Corsi P 1992 Alternative usage of initiation codons in mRNA encoding the cAMP-responsive-element modulator generates regulators with opposite functions. Proc Natl Acad Sci USA 89:4226-4230
34. Kogai T, Kanamoto Y, Li AI, Che LH, Ohashi E, Taki K, Chandraratna RA, Saito T, Brent GA 2005 Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology 146:3059-3069
35. Uyttersprot N, Miot F 1997 Dog CREM transcription factors: cloning, tissue distribution, and identification of new isoforms. Biochem Biophys Res Commun 237:74-78
36. De Vita G, Zannini M, Cirafici AM, Melillo RM, Di Lauro R, Fusco A, Santoro M 1998 Expression of the RET/PTC1 oncogene impairs the activity of TTF-1 and Pax-8 thyroid transcription factors. Cell Growth Differ 9:97-103
37. Li W, Venkataraman GM, Ain KB 2007 Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor. J Clin Endocrinol Metab 92:1080-1087
38. Hai TW, Liu F, Coukos WJ, Green MR 1989 Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev [Erratum (1990) 4:682] 3:2083-2090
39. Masquilier D, Sassone-Corsi P 1992 Transcriptional cross-talk: nuclear factors CREM and CREB bind to AP-1 sites and inhibit activation by Jun. J Biol Chem 267:22460-22466
40. Vitagliano D, Carlomagno F, Motti ML, Viglietto G, Nikiforov YE, Nikiforova MN, Hershman JM, Ryan AJ, Fusco A, Melillo RM, Santoro M 2004 Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells. Cancer Res 64:3823-3829
41. Xu J, Moatamed F, Caldwell JS, Walker JR, Kraiem Z, Taki K, Brent GA, Hershman JM 2003 Enhanced expression of nicotinamide N- methyltransferase in human papillary thyroid carcinoma cells. J Clin Endocrinol Metab 88:4990-4996