Tumor necrosis factor-α regulation of thyroid transcription factor-1 and pax-8 in rat thyroid FRTL-5 cells

Endocrinology

Volumn 140, Issue 10, 1999, Pages 4651-4658

  Ohmori, M ^a   Harii, N ^a   Endo, T ^a   Onaya, T ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; THYROID TRANSCRIPTION FACTOR 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BINDING SITE; COMPLEX FORMATION; DNA BINDING; GENE EXPRESSION; MUTATION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; REGULATORY MECHANISM; WESTERN BLOTTING;

EID: 0033305681     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.10.7021     Document Type: Article

References (47)

1. Lymphokines
2. Tumor necrosis factor and interleukin 1: Cytokines with multiple overlapping biological activities
3. Spatial correlation between thyroid epithelial cells expressing class II MHC molecules and interferon-gamma-containing lymphocytes in human thyroid autoimmune disease
4. Subacute thyroiditis
5. Effects of tumor necrosis factor-alpha/cachectin on thyroid hormone metabolism in mice
6. Impairment of hypothalamic-pituitary-thyroid function in rats treated with human recombinant tumor necrosis factor-α (cachectin)
7. Tumor necrosis factor: A putative mediator of the sick euthyroid syndrome in man
8. Alterations in thyroid function in patients with systemic illness: The 'euthyroid sick syndrome'
9. Inhibition of 125I organification and thyroid hormone release by haterleukin-1, tumor necrosis factor-a, and interferon-γ, in human thyrocytes in suspension culture
10. Influence of tumor necrosis factor-α, tumor necrosis factor-β and interferon-γ, separately and added together with interleukin-lb, on the function of cultured human thyroid cells
11. Influence of cytokines on growth and differentiated function of FRTL-5 cells
12. Suppression of rat thyrotroph and thyroid cell function by tumor necrosis factor-α
13. Tumor necrosis factor-a and interferon-γ modulate gene expression of type I 5'-deiodinase, thyroid peroxidase, and thyroglobulin in FRTL-5 rat thyroid Cells
14. A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter
15. Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity
16. Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression
17. Pax-8, a paired domain-containing proteha, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters
18. Thyroid transcription factor 1 activates the promoter of the thyrotropin receptor gene
19. Thyroid-specific expression and cyclic adenosine 3', 5'-monophosphate autoregulation of the thyrotropin receptor gene involves thyroid transcription factor-1
20. Characterization of an up-stream thyroid transcription factor-1-binding site in the thyrotropin receptor promoter
21. Characterization of a thyroid-specific enhancer located 5.5 kilobase pairs upstream of the human thyroid peroxidase gene
22. Thyroid-specific enhancer-binding protein (T/EBP): CDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1
23. Thyroid-specific gene expression
24. - symporter gene expression
25. Thyroid cells in culture
26. Firefly luciferase gene: Structure and expression in mammalian cells
27. Thyroid-stimulating hormone-induced down-regulation of thyroid transcription factor 1 in rat thyroid FRTL-5 cells
28. Cloning of the single strand DNA-binding protein important for maximal expression and thyrotropin (TSH)-induced negative regulation of the TSH receptor
29. Thyroglobulin gene activation by thyrotropin and cAMP in hormonally depleted FRTL-5 thyroid cells
30. Mediation of the hormone- and serum-dependent regulation of thyroglobulin gene expression by thyroid-transcription factors in rat thyroid FRTL-5 cells
31. TTF-2, A new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation
32. Phorbol ester down-regulation of lung surfactant protein B gene expression by cytoplasmic trapping of thyroid transcription factor-1 and hepatocyte nuclear factor 3
33. Cytokines and thyroid function
34. Effects of gammainterferon and tumor necrosis factor alpha on thyroid cells: Induction of class II antigen and inhibition of growth stimulation
35. TSH-receptor expression and human thyroid disease: Relation to clinical, endocrine, and molecular thyroid parameters
36. - symporter messenger ribonucleic acid levels in FRTL-5 cells
37. - symporter gene
38. Reversible inhibition of a thyroid-specific trans-acting factor by Ras
39. Redox regulation of thyroid-transcription factors, Pax-8 and TTF-1, is involved in their increased DNA-binding activities by thyrotropin in rat thyroid FRTL-5 cells
40. Interferon-γ, suppresses thyrotropin receptor promoter activity by reducing thyroid transcription factor-1 (TTF-1) binding to its recognition site
41. The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis
42. Protein kinase A activation of the surfactant protein B gene is mediated by phosphorylation of thyroid transcription factor 1
43. Cyclic AMP-responsive expression of the surfactant protein-A gene is mediated by increased DNA binding and transcriptional activity of thyroid transcription factor-1
44. Pax-8 expression in primary cultured dog thyrocyte is increased by cyclic AMP
45. The DNA binding activity and the dimerization ability of the thyroid transcription factor 1 are redox regulated