메뉴 건너뛰기




Volumn 102-103, Issue , 1998, Pages 59-63

Inhibition of the cAMP signaling cascade via cannabinoid receptors: A putative mechanism of immune modulation by cannabinoid compounds

Author keywords

9 Tetrahydrocanabinol; cAMP; Cannabinoids; Cannabinol; Immune suppression

Indexed keywords

ADENYLATE CYCLASE; CANNABINOID; CANNABINOID RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 4243781531     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00284-7     Document Type: Conference Paper
Times cited : (23)

References (26)
  • 1
    • 17544371574 scopus 로고    scopus 로고
    • Cannabinoid inhibition of adenylate cyclase-mediated signal transduction and IL-2 expression in the murine T cell line, EL4.IL-2
    • Condie, R., Herring, A., Koh, W.S., Lee, M., Kaminski, N.E., 1996. Cannabinoid inhibition of adenylate cyclase-mediated signal transduction and IL-2 expression in the murine T cell line, EL4.IL-2. J. Biol. Chem. 271, 13175-13183.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13175-13183
    • Condie, R.1    Herring, A.2    Koh, W.S.3    Lee, M.4    Kaminski, N.E.5
  • 2
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane, W.A., Hanus, L., Breuer, A., et al., 1992. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949.
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3
  • 3
    • 0027185227 scopus 로고
    • Anandamide, an endogenous cannabinmimetic eicosinoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction
    • Felder, C.C., Briley, E.M., Axelrod, J., Simpson, J.T., Mackie, K., Devane, W.A., 1993. Anandamide, an endogenous cannabinmimetic eicosinoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl. Acad. Sci. U.S.A. 90, 7656-7660.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 7656-7660
    • Felder, C.C.1    Briley, E.M.2    Axelrod, J.3    Simpson, J.T.4    Mackie, K.5    Devane, W.A.6
  • 4
    • 0344970328 scopus 로고    scopus 로고
    • Mechanisms of immunotoxicology by drugs of abuse: Cannabinoids and opiates
    • Smialowicz, R., Holsapple, M.P. (Eds.), CRC Press, Boca Raton
    • Freier, D.O., Fuchs, B.A., Kaminski, N.E., 1996. Mechanisms of immunotoxicology by drugs of abuse: cannabinoids and opiates. In: Smialowicz, R., Holsapple, M.P. (Eds.), Experimental Immunotoxicology. CRC Press, Boca Raton, pp. 367-388.
    • (1996) Experimental Immunotoxicology , pp. 367-388
    • Freier, D.O.1    Fuchs, B.A.2    Kaminski, N.E.3
  • 5
    • 0004935292 scopus 로고
    • Drugs of abuse and the immune system
    • Dean, J., Luster, M., Munson, A., Kimber, I. (Eds.), Raven Press, New York
    • Friedman, H., Shrivers, S.C., Klein, T.W., 1995. Drugs of abuse and the immune system. In: Dean, J., Luster, M., Munson, A., Kimber, I. (Eds.), Immunotoxicology and Immunopharmacology. Raven Press, New York, pp. 303-322.
    • (1995) Immunotoxicology and Immunopharmacology , pp. 303-322
    • Friedman, H.1    Shrivers, S.C.2    Klein, T.W.3
  • 6
    • 0029964613 scopus 로고    scopus 로고
    • Requirement for cAMP-PKA pathway activation by M phase-promoting factor in the transition from mitosis to interphase
    • Grieco, D., Porcellini, A., Avvedimento, E.V., Gottesman, M.E., 1996. Requirement for cAMP-PKA pathway activation by M phase-promoting factor in the transition from mitosis to interphase. Science 271, 1718-1723.
    • (1996) Science , vol.271 , pp. 1718-1723
    • Grieco, D.1    Porcellini, A.2    Avvedimento, E.V.3    Gottesman, M.E.4
  • 7
    • 0015408807 scopus 로고
    • Guanosine 3′:5′-cyclic monophosphates: A possible intracellular mediator of mitogenic influences in lymphocytes
    • Hadden, J.W., Hadden, E.M., Haddox, M.K., Goldberg, N.D., 1972. Guanosine 3′:5′-cyclic monophosphates: a possible intracellular mediator of mitogenic influences in lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 69, 3024-3027.
    • (1972) Proc. Natl. Acad. Sci. U.S.A. , vol.69 , pp. 3024-3027
    • Hadden, J.W.1    Hadden, E.M.2    Haddox, M.K.3    Goldberg, N.D.4
  • 8
    • 0032055664 scopus 로고    scopus 로고
    • Inhibiting of the cAMP signaling cascade and nuclear factor binding to CRE and κB elements by cannabinol, a minimally CNS-active cannabinoid
    • Herring, A., Koh, W.S., Kaminski, N.E., 1998. Inhibiting of the cAMP signaling cascade and nuclear factor binding to CRE and κB elements by cannabinol, a minimally CNS-active cannabinoid. Biochem. Pharmacol. 55, 1013-1023.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1013-1023
    • Herring, A.1    Koh, W.S.2    Kaminski, N.E.3
  • 9
    • 0029050265 scopus 로고
    • c-jun N-Terminal kinase but not mitogen-activated protein kinase is sensitive to cAMP inhibition in T lymphocytes
    • Hsueh, Y.P., Lai, M.Z., 1995. c-jun N-Terminal kinase but not mitogen-activated protein kinase is sensitive to cAMP inhibition in T lymphocytes. J. Biol. Chem. 270, 18094-18098.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18094-18098
    • Hsueh, Y.P.1    Lai, M.Z.2
  • 11
    • 0002068986 scopus 로고
    • Mechanisms of immune modulation by cannabinoids
    • Dean, J., Luster, M., Munson, A., Kimber, I. (Eds.), Raven Press, New York
    • Kaminski, N.E., 1994. Mechanisms of immune modulation by cannabinoids. In: Dean, J., Luster, M., Munson, A., Kimber, I. (Eds.), Immunopharmacology and Immunotoxicology. Raven Press, New York, pp. 349-362.
    • (1994) Immunopharmacology and Immunotoxicology , pp. 349-362
    • Kaminski, N.E.1
  • 12
    • 0027998221 scopus 로고
    • Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G protein coupled mechanism
    • Kaminski, N.E., Koh, W.S., Lee, M., Yang, K.H., Kessler, F.K., 1994. Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G protein coupled mechanism. Biochem. Pharmacol. 48, 1899-1908.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1899-1908
    • Kaminski, N.E.1    Koh, W.S.2    Lee, M.3    Yang, K.H.4    Kessler, F.K.5
  • 13
    • 0023938335 scopus 로고
    • The adenylate cyclase-cAMP-protein kinase a pathway and regulation of the immune response
    • Kammer, G.M., 1988. The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response. Immunol. Today 9, 222-229.
    • (1988) Immunol. Today , vol.9 , pp. 222-229
    • Kammer, G.M.1
  • 15
    • 0029561788 scopus 로고
    • Effect of putative endogenous cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes
    • Lee, M., Yang, K.H., Kaminski, N.B., 1995. Effect of putative endogenous cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes. J. Pharmacol. Exp. Ther. 275, 529-536.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 529-536
    • Lee, M.1    Yang, K.H.2    Kaminski, N.B.3
  • 16
    • 0021220418 scopus 로고
    • Inhibition of human B cell activation by diterpine forskolin: Interference with B cell growth factor-induced G1 to S transition of the B cell cycle
    • Maraguchi, A., Miyazaki, K., Fauci, A.S., 1984. Inhibition of human B cell activation by diterpine forskolin: Interference with B cell growth factor-induced G1 to S transition of the B cell cycle. J. Immunol. 133, 1283-1287.
    • (1984) J. Immunol. , vol.133 , pp. 1283-1287
    • Maraguchi, A.1    Miyazaki, K.2    Fauci, A.S.3
  • 17
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda, L.A., Lolait, S.J., Brownstein, M.J., Young, A.C., Bonner, T.I., 1990. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature (London) 346, 561-564.
    • (1990) Nature (London) , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 18
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-monoglyceride present in canine gut, that binds to cannabinoid receptors
    • Mechoulam, R., Ben-Shabat, S., Hanus, L., et al., 1995. Identification of an endogenous 2-monoglyceride present in canine gut, that binds to cannabinoid receptors. Biochem. Pharmacol. 50, 83-90.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3
  • 19
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro, S., Thomas, K.L., Abu-Shaar, M., 1993. Molecular characterization of a peripheral receptor for cannabinoids. Nature (London) 365, 61-65.
    • (1993) Nature (London) , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 20
    • 0028008963 scopus 로고
    • Flow cytometric detection of the RI alpha subunit of type-I cAMP-dependent protein kinase in human cells
    • Pepe, S., Ruggiero, A., Tortora, G., et al., 1994. Flow cytometric detection of the RI alpha subunit of type-I cAMP-dependent protein kinase in human cells. Cytometry 15, 73-79.
    • (1994) Cytometry , vol.15 , pp. 73-79
    • Pepe, S.1    Ruggiero, A.2    Tortora, G.3
  • 21
    • 0017796062 scopus 로고
    • Type I cyclic AMP-dependent protein kinase as a positive effector of growth
    • Russell, D.H., 1978. Type I cyclic AMP-dependent protein kinase as a positive effector of growth. Adv. Cyclic Nucleotide Res. 9, 493-506.
    • (1978) Adv. Cyclic Nucleotide Res. , vol.9 , pp. 493-506
    • Russell, D.H.1
  • 22
    • 0027166278 scopus 로고
    • 9-Tetrahydro-canabinol selectively inhibits T cell dependent humoral immune responses through direct inhibition of accessory T cell function
    • 9-Tetrahydro-canabinol selectively inhibits T cell dependent humoral immune responses through direct inhibition of accessory T cell function. Immunopharmacology 26, 129-137.
    • (1993) Immunopharmacology , vol.26 , pp. 129-137
    • Schatz, A.R.1    Koh, W.S.2    Kaminski, N.E.3
  • 23
    • 0031062297 scopus 로고    scopus 로고
    • Cannabinoid receptors CB1 and CB2: A characterization of expression and adenylate cyclase modulation within the immune system
    • Schatz, A.R., Lee, M., Condie, R., Pulaski, J., Kaminski, N.E., 1997. Cannabinoid receptors CB1 and CB2: a characterization of expression and adenylate cyclase modulation within the immune system. Toxicol. Appl. Pharmacol. 142, 278-287.
    • (1997) Toxicol. Appl. Pharmacol. , vol.142 , pp. 278-287
    • Schatz, A.R.1    Lee, M.2    Condie, R.3    Pulaski, J.4    Kaminski, N.E.5
  • 24
    • 0015014036 scopus 로고
    • Cyclic adenosine 3′,5′-monophosphate in human lymphocytes. Alteration after phytohemagglutinin
    • Smith, J.W., Steiner, A.L., Newberry, W.M., Parker, C.W., 1971. Cyclic adenosine 3′,5′-monophosphate in human lymphocytes. Alteration after phytohemagglutinin. J. Clin. Invest. 50, 432-441.
    • (1971) J. Clin. Invest. , vol.50 , pp. 432-441
    • Smith, J.W.1    Steiner, A.L.2    Newberry, W.M.3    Parker, C.W.4
  • 25
    • 0029016332 scopus 로고
    • Cyclic AMP inhibits expression of the IL-2 gene through the nuclear factor of activated T cells (NF-AT) site, and transfection of NF-AT cDNAs abrogates the sensitivity of EL-4 cells to cyclic AMP
    • Tsuruta, L., Lee, H., Masuda, E., et al., 1995. Cyclic AMP inhibits expression of the IL-2 gene through the nuclear factor of activated T cells (NF-AT) site, and transfection of NF-AT cDNAs abrogates the sensitivity of EL-4 cells to cyclic AMP. J. Immunol. 154, 5255-5264.
    • (1995) J. Immunol. , vol.154 , pp. 5255-5264
    • Tsuruta, L.1    Lee, H.2    Masuda, E.3
  • 26
    • 0027973059 scopus 로고
    • Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells
    • Watson, P., Krupinski, J., Kempinski, A., Frankenfield, C., 1994. Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells. J. Biol. Chem. 269, 28893-28898.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28893-28898
    • Watson, P.1    Krupinski, J.2    Kempinski, A.3    Frankenfield, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.