Synthesis of a 2, 4, 8-trisubstituted pyrimidino[5, 4-d]pyrimidine library via sequential SNAr reactions on solid-phase

Combinatorial Chemistry and High Throughput Screening

Volumn 7, Issue 5, 2004, Pages 413-421

  El Araby, M ^a   Pottorf, R S ^a   Player, M R ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

ATP analogue; Combinatorial; Kinase inhibitor; Parallel synthesis; Pyrimidinopyrimidine; SNAr

Indexed keywords

AMINE; ANILINE DERIVATIVE; HETEROCYCLIC COMPOUND; PYRIMIDINE DERIVATIVE; PYRIMIDINO[5,4 D]PYRIMIDINE; RESIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SOLID PHASE SYNTHESIS; SYNTHESIS;

EID: 4243184985     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/1386207043328571     Document Type: Article

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