메뉴 건너뛰기




Volumn 47, Issue 16, 2008, Pages 4808-4816

Functional segregation of a predicted "hinge" site within the β-strand linkers of Escherichia coli leucyl-tRNA synthetase

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; COMPUTATIONAL METHODS; CRYSTAL STRUCTURE; REACTION KINETICS; RNA;

EID: 42349092094     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702494q     Document Type: Article
Times cited : (14)

References (34)
  • 1
    • 0013019697 scopus 로고    scopus 로고
    • and, Eds, Landes Bioscience/Eurekah.com, Georgetown, TX
    • Ibba, M., Francklyn, C., and Cusack, S., Eds. (2005) Aminoacyl-tRNA Synthetases Landes Bioscience/Eurekah.com, Georgetown, TX.
    • (2005) Aminoacyl-tRNA Synthetases
  • 2
    • 42349103482 scopus 로고    scopus 로고
    • Fidelity mechanisms of the aminoacyl-tRNA synthetases
    • RajBhandary, U. L, and Kohrer, C, Eds, Springer-Verlag, Berlin in press
    • Mascarenhas, A. P., An, S., Rosen, A. E., Martinis, S. A., and Musier-Forsyth, K. (2008) Fidelity mechanisms of the aminoacyl-tRNA synthetases, in Protein Engineering (RajBhandary, U. L., and Kohrer, C., Eds.) Springer-Verlag, Berlin (in press).
    • (2008) Protein Engineering
    • Mascarenhas, A.P.1    An, S.2    Rosen, A.E.3    Martinis, S.A.4    Musier-Forsyth, K.5
  • 3
    • 2342431929 scopus 로고    scopus 로고
    • Transfer RNA-dependent amino acid discrimination by aminoacyl-tRNA synthetases
    • Lapointe, J, and Brakier-Gingras, L, Eds, pp, Kluwer Academic/Plenum Publishers, Dordrecht, The Netherlands
    • Hendrickson, T. L., and Schimmel, P. (2003) Transfer RNA-dependent amino acid discrimination by aminoacyl-tRNA synthetases, in Translation Mechanisms (Lapointe, J., and Brakier-Gingras, L., Eds.) pp 35-64, Kluwer Academic/Plenum Publishers, Dordrecht, The Netherlands.
    • (2003) Translation Mechanisms , pp. 35-64
    • Hendrickson, T.L.1    Schimmel, P.2
  • 4
    • 0141653988 scopus 로고    scopus 로고
    • Amino acid discrimination by a highly differentiated metal center of an aminoacyl-tRNA synthetase
    • Zhang, C. M., Perona, J. J., and Hou, Y. M. (2003) Amino acid discrimination by a highly differentiated metal center of an aminoacyl-tRNA synthetase. Biochemistry 42, 10931-10937.
    • (2003) Biochemistry , vol.42 , pp. 10931-10937
    • Zhang, C.M.1    Perona, J.J.2    Hou, Y.M.3
  • 6
    • 0017326738 scopus 로고
    • Editing mechanisms in protein synthesis. Rejection of valine by the isoleucyl-tRNA synthetase
    • Fersht, A. R. (1977) Editing mechanisms in protein synthesis. Rejection of valine by the isoleucyl-tRNA synthetase. Biochemistry 16, 1025-1030.
    • (1977) Biochemistry , vol.16 , pp. 1025-1030
    • Fersht, A.R.1
  • 7
    • 33748785965 scopus 로고    scopus 로고
    • Pre-transfer editing by class II prolyl-tRNA synthetase: Role of aminoacylation active site in "selective release" of noncognate amino acids
    • Hati, S., Ziervogel, B., Sternjohn, J., Wong, F. C., Nagan, M. C., Rosen, A. E., Siliciano, P. G., Chihade, J. W., and Musier-Forsyth, K. (2006) Pre-transfer editing by class II prolyl-tRNA synthetase: Role of aminoacylation active site in "selective release" of noncognate amino acids. J. Biol. Chem. 281, 27862-27872.
    • (2006) J. Biol. Chem , vol.281 , pp. 27862-27872
    • Hati, S.1    Ziervogel, B.2    Sternjohn, J.3    Wong, F.C.4    Nagan, M.C.5    Rosen, A.E.6    Siliciano, P.G.7    Chihade, J.W.8    Musier-Forsyth, K.9
  • 8
    • 0346848759 scopus 로고    scopus 로고
    • On the evolution of structure in aminoacyl-tRNA synthetases
    • O'Donoghue, P., and Luthey-Schulten, Z. (2003) On the evolution of structure in aminoacyl-tRNA synthetases. Microbiol. Mol. Biol. Rev. 67, 550-573.
    • (2003) Microbiol. Mol. Biol. Rev , vol.67 , pp. 550-573
    • O'Donoghue, P.1    Luthey-Schulten, Z.2
  • 9
    • 0034657687 scopus 로고    scopus 로고
    • The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue
    • Cusack, S., Yaremchuk, A., and Tukalo, M. (2000) The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue. EMBO J. 19, 2351-2361.
    • (2000) EMBO J , vol.19 , pp. 2351-2361
    • Cusack, S.1    Yaremchuk, A.2    Tukalo, M.3
  • 11
    • 0034703763 scopus 로고    scopus 로고
    • Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase
    • Fukai, S., Nureki, O., Sekine, S., Shimada, A., Tao, J., Vassylyev, D. G., and Yokoyama, S. (2000) Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase. Cell 103, 793-803.
    • (2000) Cell , vol.103 , pp. 793-803
    • Fukai, S.1    Nureki, O.2    Sekine, S.3    Shimada, A.4    Tao, J.5    Vassylyev, D.G.6    Yokoyama, S.7
  • 12
    • 0024431811 scopus 로고
    • Insertion of new sequences into the catalytic domain of an enzyme
    • Starzyk, R. M., Burbaum, J. J., and Schimmel, P. (1989) Insertion of new sequences into the catalytic domain of an enzyme. Biochemistry 28, 8479-8484.
    • (1989) Biochemistry , vol.28 , pp. 8479-8484
    • Starzyk, R.M.1    Burbaum, J.J.2    Schimmel, P.3
  • 14
    • 27144520077 scopus 로고    scopus 로고
    • Leu reveal two modes of discriminator base recognition
    • Leu reveal two modes of discriminator base recognition. Nat. Struct. Mol. Biol. 12, 915-922.
    • (2005) Nat. Struct. Mol. Biol , vol.12 , pp. 915-922
    • Fukunaga, R.1    Yokoyama, S.2
  • 15
    • 0031301321 scopus 로고    scopus 로고
    • Martinis, S. A., and Fox, G. E. (1997) Non-standard amino acid recognition by Escherichia coli leucyl-tRNA synthetase. Nucleic Acids Symp. Ser. 36, 125-128.
    • Martinis, S. A., and Fox, G. E. (1997) Non-standard amino acid recognition by Escherichia coli leucyl-tRNA synthetase. Nucleic Acids Symp. Ser. 36, 125-128.
  • 17
  • 18
    • 0023953676 scopus 로고
    • Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro
    • Sampson, J. R., and Uhlenbeck, O. C. (1988) Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro. Proc. Natl. Acad. Sci. U.S.A. 85, 1033-1037.
    • (1988) Proc. Natl. Acad. Sci. U.S.A , vol.85 , pp. 1033-1037
    • Sampson, J.R.1    Uhlenbeck, O.C.2
  • 19
    • 0023840230 scopus 로고
    • ompT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification
    • Grodberg, J., and Dunn, J. J. (1988) ompT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification. J. Bacteriol. 170, 1245-1253.
    • (1988) J. Bacteriol , vol.170 , pp. 1245-1253
    • Grodberg, J.1    Dunn, J.J.2
  • 20
    • 28244498723 scopus 로고    scopus 로고
    • Two conserved threonines collaborate in the Escherichia coli leucyl-tRNA synthetase amino acid editing mechanism
    • Zhai, Y., and Martinis, S. A. (2005) Two conserved threonines collaborate in the Escherichia coli leucyl-tRNA synthetase amino acid editing mechanism. Biochemistry 44, 15437-15443.
    • (2005) Biochemistry , vol.44 , pp. 15437-15443
    • Zhai, Y.1    Martinis, S.A.2
  • 21
    • 0015522966 scopus 로고
    • Transfer ribonucleic acid synthetase catalyzed deacylation of aminoacyl transfer ribonucleic acid in the absence of adenosine monophosphate and pyrophosphate
    • Schreier, A. A., and Schimmel, P. R. (1972) Transfer ribonucleic acid synthetase catalyzed deacylation of aminoacyl transfer ribonucleic acid in the absence of adenosine monophosphate and pyrophosphate. Biochemistry 11, 1582-1589.
    • (1972) Biochemistry , vol.11 , pp. 1582-1589
    • Schreier, A.A.1    Schimmel, P.R.2
  • 22
    • 0038345361 scopus 로고    scopus 로고
    • The tRNA Synthetase Proofreading and Editing Active Sites: A Novel Antibiotic Target
    • Lincecum, T. L., and Martinis, S. A. (2000) The tRNA Synthetase Proofreading and Editing Active Sites: A Novel Antibiotic Target. SAAS Bull. Biochem. Biotechnol. 13, 25-33.
    • (2000) SAAS Bull. Biochem. Biotechnol , vol.13 , pp. 25-33
    • Lincecum, T.L.1    Martinis, S.A.2
  • 24
    • 0032530836 scopus 로고    scopus 로고
    • A database of macromolecular motions
    • Gerstein, M., and Krebs, W. (1998) A database of macromolecular motions. Nucleic Acids Res. 26, 4280-4290.
    • (1998) Nucleic Acids Res , vol.26 , pp. 4280-4290
    • Gerstein, M.1    Krebs, W.2
  • 25
    • 0034655949 scopus 로고    scopus 로고
    • The morph server: A standardized system for analyzing and visualizing macromolecular motions in a database framework
    • Krebs, W. G., and Gerstein, M. (2000) The morph server: A standardized system for analyzing and visualizing macromolecular motions in a database framework. Nucleic Acids Res. 28, 1665-1675.
    • (2000) Nucleic Acids Res , vol.28 , pp. 1665-1675
    • Krebs, W.G.1    Gerstein, M.2
  • 26
    • 34547650902 scopus 로고    scopus 로고
    • FlexOracle: Predicting flexible hinges by identification of stable domains
    • Flores, S. C., and Gerstein, M. B. (2007) FlexOracle: Predicting flexible hinges by identification of stable domains. BMC Bioinf. 8, 215.
    • (2007) BMC Bioinf , vol.8 , pp. 215
    • Flores, S.C.1    Gerstein, M.B.2
  • 27
    • 23844520061 scopus 로고    scopus 로고
    • A molecular viewer for the analysis of TLS rigid-body motion in macromolecules
    • Painter, J., and Merritt, E. A. (2005) A molecular viewer for the analysis of TLS rigid-body motion in macromolecules. Acta Crystallogr. D61, 465-471.
    • (2005) Acta Crystallogr , vol.D61 , pp. 465-471
    • Painter, J.1    Merritt, E.A.2
  • 28
    • 0037178055 scopus 로고    scopus 로고
    • Rational design to block amino acid editing of a tRNA synthetase
    • Mursinna, R. S., and Martinis, S. A. (2002) Rational design to block amino acid editing of a tRNA synthetase. J. Am. Chem. Soc. 124, 7286-7287.
    • (2002) J. Am. Chem. Soc , vol.124 , pp. 7286-7287
    • Mursinna, R.S.1    Martinis, S.A.2
  • 29
    • 33746189733 scopus 로고    scopus 로고
    • Distinct kinetic mechanisms of the two classes of aminoacyl-tRNA synthetases
    • Zhang, C. M., Perona, J. J., Ruy, K., Francklyn, C. S., and Hou, Y. M. (2006) Distinct kinetic mechanisms of the two classes of aminoacyl-tRNA synthetases. J. Mol. Biol. 361, 300-311.
    • (2006) J. Mol. Biol , vol.361 , pp. 300-311
    • Zhang, C.M.1    Perona, J.J.2    Ruy, K.3    Francklyn, C.S.4    Hou, Y.M.5
  • 31
    • 33847132709 scopus 로고    scopus 로고
    • Molecular and functional dissection of a putative RNA-binding region in yeast mitochondrial leucyl-tRNA synthetase
    • Nawaz, M. H., Pang, Y. L., and Martinis, S. A. (2007) Molecular and functional dissection of a putative RNA-binding region in yeast mitochondrial leucyl-tRNA synthetase. J. Mol. Biol. 367, 384-394.
    • (2007) J. Mol. Biol , vol.367 , pp. 384-394
    • Nawaz, M.H.1    Pang, Y.L.2    Martinis, S.A.3
  • 32
    • 0037457957 scopus 로고    scopus 로고
    • Interstice mutations that block site-to-site translocation of a misactivated amino acid bound to a class I tRNA synthetase
    • Bishop, A. C., Beebe, K., and Schimmel, P. R. (2003) Interstice mutations that block site-to-site translocation of a misactivated amino acid bound to a class I tRNA synthetase. Proc. Natl. Acad. Sci. U.S.A. 100, 490-494.
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 490-494
    • Bishop, A.C.1    Beebe, K.2    Schimmel, P.R.3
  • 33
    • 33644858728 scopus 로고    scopus 로고
    • Mutational unmasking of a tRNA-dependent pathway for preventing genetic code ambiguity
    • Williams, A. M., and Martinis, S. A. (2006) Mutational unmasking of a tRNA-dependent pathway for preventing genetic code ambiguity. Proc. Natl. Acad. Sci. U.S.A. 103, 3586-3591.
    • (2006) Proc. Natl. Acad. Sci. U.S.A , vol.103 , pp. 3586-3591
    • Williams, A.M.1    Martinis, S.A.2
  • 34
    • 0030013766 scopus 로고    scopus 로고
    • BCM Search Launcher: An integrated interface to molecular biology data base search and analysis services available on the World Wide Web
    • Smith, R. F., Wiese, B. A., Wojzynski, M. K., Davison, D. B., and Worley, K. C. (1996) BCM Search Launcher: An integrated interface to molecular biology data base search and analysis services available on the World Wide Web. Genome Res. 6, 454-462.
    • (1996) Genome Res , vol.6 , pp. 454-462
    • Smith, R.F.1    Wiese, B.A.2    Wojzynski, M.K.3    Davison, D.B.4    Worley, K.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.