메뉴 건너뛰기




Volumn 8, Issue 4, 2008, Pages 515-517

Drug cocktails for effective treatment of glioblastoma multiforme

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIN; EPHRIN RECEPTOR A2; EXOTOXIN; INTERLEUKIN 13 RECEPTOR ALPHA2; TRANSCRIPTION FACTOR FRA 1;

EID: 42249089350     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/14737175.8.4.515     Document Type: Editorial
Times cited : (16)

References (20)
  • 1
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987-996 (2005).
    • (2005) N. Engl. J. Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 2
    • 33644670748 scopus 로고    scopus 로고
    • Local treatment of malignant brain tumors using implantable chemotherapeutic polymers
    • Gallia GL, Brem S, Brem H. Local treatment of malignant brain tumors using implantable chemotherapeutic polymers. J. Natl Compr. Canc. Netw. 3, 721-728 (2005).
    • (2005) J. Natl Compr. Canc. Netw , vol.3 , pp. 721-728
    • Gallia, G.L.1    Brem, S.2    Brem, H.3
  • 3
    • 0036053691 scopus 로고    scopus 로고
    • Local treatment of brain tumors with targeted chimera cytotoxic proteins
    • Debinski W. Local treatment of brain tumors with targeted chimera cytotoxic proteins. Cancer Invest. 20, 801-809 (2002).
    • (2002) Cancer Invest , vol.20 , pp. 801-809
    • Debinski, W.1
  • 4
    • 0028859363 scopus 로고
    • Human glioma cells over-express receptor for IL13 and are extremely sensitive to a novel chimeric protein composed of IL13 and Pseudomonas exotoxin
    • Debinski W, Obiri NI, Powers SK, Pastan I, Puri RK. Human glioma cells over-express receptor for IL13 and are extremely sensitive to a novel chimeric protein composed of IL13 and Pseudomonas exotoxin. Clin. Cancer Res. 1, 1253-1258 (1995).
    • (1995) Clin. Cancer Res , vol.1 , pp. 1253-1258
    • Debinski, W.1    Obiri, N.I.2    Powers, S.K.3    Pastan, I.4    Puri, R.K.5
  • 5
    • 33947547455 scopus 로고    scopus 로고
    • Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: A report by the Cintredekin Besudotox Intraparenchymal Study Group
    • Kunwar S, Prados MD, Chang SM et al. Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group. J. Clin. Oncol. 25, 837-844 (2007).
    • (2007) J. Clin. Oncol , vol.25 , pp. 837-844
    • Kunwar, S.1    Prados, M.D.2    Chang, S.M.3
  • 6
    • 42249084323 scopus 로고    scopus 로고
    • Results from PRECISE: A randomized Phase 3 study in patients with first recurrent GBM comparing Cintredekin Besudotox administered via convection-enhanced delivery with Gliadel wafers
    • As in [5, this study establishes clinical efficacy of a recombinant cytotoxin in patients with glioblastoma multiforme GBM, ••
    • Kunwar S, Westphal M, Medhorn M et al. Results from PRECISE: a randomized Phase 3 study in patients with first recurrent GBM comparing Cintredekin Besudotox administered via convection-enhanced delivery with Gliadel wafers. Neuro-oncology 9, 531 (2007). •• As in [5], this study establishes clinical efficacy of a recombinant cytotoxin in patients with glioblastoma multiforme (GBM).
    • (2007) Neuro-oncology , vol.9 , pp. 531
    • Kunwar, S.1    Westphal, M.2    Medhorn, M.3
  • 7
    • 33845698912 scopus 로고    scopus 로고
    • Expression of nine tumour antigens in a series of human glioblastoma multiforme: Interest of EGFRvIII, IL-13Rα2, gp100 and TRP-2 for immunotherapy
    • Saikali S, Avril T, Collet B et al. Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Rα2, gp100 and TRP-2 for immunotherapy. J. Neurooncol. 81, 139-148 (2007).
    • (2007) J. Neurooncol , vol.81 , pp. 139-148
    • Saikali, S.1    Avril, T.2    Collet, B.3
  • 8
    • 33846886376 scopus 로고    scopus 로고
    • Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics
    • Demonstrates an interesting profile of antigens found in GBM suitable for targeting using multivalent vaccines, •
    • Zhang JG, Eguchi J, Kruse C et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin. Cancer Res. 13, 566-575 (2007). • Demonstrates an interesting profile of antigens found in GBM suitable for targeting using multivalent vaccines.
    • (2007) Clin. Cancer Res , vol.13 , pp. 566-575
    • Zhang, J.G.1    Eguchi, J.2    Kruse, C.3
  • 9
    • 0344810314 scopus 로고    scopus 로고
    • Growth factor expression varies among high grade gliomas and normal brain: Epidermal growth factor receptor has excellent properties for interstitial fusion protein therapy
    • Liu TF, Tatter SB, Willingham MC, Yang MY, Hu J, Frankel A. Growth factor expression varies among high grade gliomas and normal brain: epidermal growth factor receptor has excellent properties for interstitial fusion protein therapy. Mol. Cancer Ther. 2(8), 783-787 (2003).
    • (2003) Mol. Cancer Ther , vol.2 , Issue.8 , pp. 783-787
    • Liu, T.F.1    Tatter, S.B.2    Willingham, M.C.3    Yang, M.Y.4    Hu, J.5    Frankel, A.6
  • 10
    • 40749096452 scopus 로고    scopus 로고
    • IL-13 Receptor α-2, EphA2, and Fra-1 as molecular denominators of high-grade astrocytomas and specific targets for combinatorial therapy
    • Establishes first ever documented trimolecular signature of GBM, ••
    • Wykosky J, Gibo DM, Stanton C, Debinski W. IL-13 Receptor α-2, EphA2, and Fra-1 as molecular denominators of high-grade astrocytomas and specific targets for combinatorial therapy. Clin. Cancer Res. 14, 199-208 (2008). •• Establishes first ever documented trimolecular signature of GBM.
    • (2008) Clin. Cancer Res , vol.14 , pp. 199-208
    • Wykosky, J.1    Gibo, D.M.2    Stanton, C.3    Debinski, W.4
  • 11
    • 0037381008 scopus 로고    scopus 로고
    • Gene expression-based classification of malignant gliomas correlated better with survival than histological classification
    • Nutt CL, Mani DR, Betensky RA et al. Gene expression-based classification of malignant gliomas correlated better with survival than histological classification. Cancer Res. 63, 1602-1607 (2003).
    • (2003) Cancer Res , vol.63 , pp. 1602-1607
    • Nutt, C.L.1    Mani, D.R.2    Betensky, R.A.3
  • 12
    • 27644466229 scopus 로고    scopus 로고
    • EphA2 as a novel molecular marker and target in glioblastoma multiforme
    • Wykosky J, Gibo DM, Stanton C, Debinski W. EphA2 as a novel molecular marker and target in glioblastoma multiforme. Mol. Cancer Res. 3, 541-551 (2005).
    • (2005) Mol. Cancer Res , vol.3 , pp. 541-551
    • Wykosky, J.1    Gibo, D.M.2    Stanton, C.3    Debinski, W.4
  • 13
    • 33845332412 scopus 로고    scopus 로고
    • A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma
    • Liu F, Park PJ, Lai W et al. A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma. Cancer Res. 66, 10815-10823 (2006).
    • (2006) Cancer Res , vol.66 , pp. 10815-10823
    • Liu, F.1    Park, P.J.2    Lai, W.3
  • 14
    • 37549047649 scopus 로고    scopus 로고
    • A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor-expressing tumor cells
    • Wykosky J, Gibo DM, Debinski W. A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor-expressing tumor cells. Mol. Cancer Ther. 6, 3208-3218 (2007)
    • (2007) Mol. Cancer Ther , vol.6 , pp. 3208-3218
    • Wykosky, J.1    Gibo, D.M.2    Debinski, W.3
  • 15
    • 0344364573 scopus 로고    scopus 로고
    • Combination fusion protein therapy of refractory brain tumors: Demonstration of efficacy in cell culture
    • Liu TF, Willingham MC, Tatter SB et al. Combination fusion protein therapy of refractory brain tumors: demonstration of efficacy in cell culture. J. Neurooncol. 65(1), 77-85 (2003).
    • (2003) J. Neurooncol , vol.65 , Issue.1 , pp. 77-85
    • Liu, T.F.1    Willingham, M.C.2    Tatter, S.B.3
  • 16
    • 38649092392 scopus 로고    scopus 로고
    • Anti-glioblastoma effect of a recombinant bi-specific cytotoxin co-targeting human IL-13 and EGF receptors in a mouse xenograft model
    • Demonstrates better efficacy of double-targeting of GBM with recombinant cytotoxins, •
    • Stish BJ, Chen H, Shu Y, Panoskaltsis-Mortari A, Vallera DA. Anti-glioblastoma effect of a recombinant bi-specific cytotoxin co-targeting human IL-13 and EGF receptors in a mouse xenograft model. J. Neurooncol. 87(1), 51-61 (2008). • Demonstrates better efficacy of double-targeting of GBM with recombinant cytotoxins.
    • (2008) J. Neurooncol , vol.87 , Issue.1 , pp. 51-61
    • Stish, B.J.1    Chen, H.2    Shu, Y.3    Panoskaltsis-Mortari, A.4    Vallera, D.A.5
  • 17
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor TT, Sorensen AG, di Tomaso E et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11(1), 83-95 (2007).
    • (2007) Cancer Cell , vol.11 , Issue.1 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    di Tomaso, E.3
  • 18
    • 0035718735 scopus 로고    scopus 로고
    • VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme
    • Debinski W, Slagle-Webb B, Achen MG et al. VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme. Mol. Med. 7, 598-608 (2001).
    • (2001) Mol. Med , vol.7 , pp. 598-608
    • Debinski, W.1    Slagle-Webb, B.2    Achen, M.G.3
  • 19
    • 33646260685 scopus 로고    scopus 로고
    • Using molecular information to guide brain tumor therapy
    • Mischel PS, Cloughesy T. Using molecular information to guide brain tumor therapy. Nat. Clin. Pract. Neurol. 2(5), 232-233 (2006).
    • (2006) Nat. Clin. Pract. Neurol , vol.2 , Issue.5 , pp. 232-233
    • Mischel, P.S.1    Cloughesy, T.2
  • 20
    • 23844528834 scopus 로고    scopus 로고
    • Personalized, multivalent, and more affordable: The globalization of vaccines
    • Debinski W. Personalized, multivalent, and more affordable: the globalization of vaccines. Clin. Cancer Res. 11, 5663-5664 (2005).
    • (2005) Clin. Cancer Res , vol.11 , pp. 5663-5664
    • Debinski, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.