Biochemical and histopathologic effects of omeprazole and vitamin E in rats with corrosive esophageal burns

Pediatric Surgery International

Volumn 24, Issue 5, 2008, Pages 555-560

  Topaloglu, Banu ^a   Bicakci, Unal ^a   Tander, Burak ^a   Ariturk, Ender ^a   Kilicoglu Aydin, Birsen ^a   Aydin, Oguz ^a   Rizalar, Riza ^a   Ayyildiz, Suat H ^a   Bernay, Ferit ^a  

^a ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

Caustic ingestion; Esophageal burn; Omeprazole; Vitamin E

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; ACID; ALKALI; ALPHA TOCOPHEROL; GLUTATHIONE; HYDROXYPROLINE; MALONALDEHYDE; OMEPRAZOLE; PROTEIN; SULFURIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CAUSTIC BURN; CONTROLLED STUDY; DRUG EFFECT; ESOPHAGUS; ESOPHAGUS BURN; HISTOPATHOLOGY; LAPAROTOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; WISTAR ALBINO GLAXO RAT;

ANIMALS; ANTI-ULCER AGENTS; ANTIOXIDANTS; BURNS, CHEMICAL; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; ESOPHAGUS; GLUTATHIONE; HYDROXYPROLINE; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAPERITONEAL; MALONDIALDEHYDE; OMEPRAZOLE; RATS; RATS, WISTAR; TREATMENT OUTCOME; VITAMIN E;

EID: 42149179852     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-008-2126-8     Document Type: Article

References (35)

1. Nayci A, Cakmak M, Renda N, Erekul S (1997) The effect of corticosteroids and pentoxiflline in inhibition of wound healing in corrosive esophageal burns: a prospective randomised trial in rats. Int J Surg 82:371-375
2. Bingol KM, Tanyel FC, Muftuoglu S, Renda N (1999) The preventive effect of heparin on stricture formation after caustic esophageal burns. J Pediatr Surg 32:291-294
3. Pintus C, Manzoni C, Nappo S, Perrelli L (1993) Caustic ingestion in childhood: current treatment possibilities and their complications. Pediatr Surg Int 8:109-112
4. Adam JS, Birck HG (1982) Pediatric caustic ingestion. Ann Otol Rhinol Laryngol 91:656-658
5. Tanyel FC, Buyukpamukcu N, Hicsonmez A (1988) The place of steroids, antibiotics and early bougienage combination in the treatment of caustic esophageal burns in childhood. Turk J Pediatr 30:253-257
6. Gundogdu HZ, Tanyel FC, Buyukpamukcu N (1992) Conservative treatment of caustic esophageal strictures. J Pediatr Surg 27:767-770
7. Robert A. Fisher, Eckhauser ML, Radivoyevitch M (1985) Acid ingestion in an experimental model. Surg Gynecol Obstetr 161:91-99
8. Tander B, Baskaya H, Ariturk E, Rizalar R (2003) Balon dilatation in esophageal stricures. In: Colloquium on gastroesophageal reflux and esophageal strictures. Izmir, Turkey
9. Demirbilek S, Bernay F, Rizalar R, Sancar B (1994) Effects of estradiol and progesterone on the synthesis of collagen in corrosive esophageal burns in rats. J Pediatr Surg 29:1425-1428
10. Hawkins DB, Demeter MJ, Bornett TE (1980) Caustic ingestion-controversies in management: a review of 214 cases. Laryngoscope 90:98-109
11. Liu AJ, Richardson MA (1985) Effects of N-acetylcysteine on experimentally induced esophageal lye injury. Ann Otol Rhinol Laryngol 94:477-482
12. Haller JA, Bachman K (1964) The comparative effect of current therapy on experimental caustic burns of the esophagus. Pediatrics 6:235-245
13. Haller JA (1971) Pathophysiology and management of acute corrosive burns of the esophagus: results of treatment in 285 children. J Pediatr Surg 6:587-584
14. Apaydin BB, Paksoy M, Artis T, Sahin DA (2001) Influence of pentoxifylline and interferon-alfa on prevention of stricture due to corrosive esophagitis. Eur Surg Res 33:225-231
15. Gunel E, Caglayan F, Caglayan O, AkIllIoglu I (1999) Reactive oxygen radical levels in caustic esophageal burns. J Pediatr Surg 34:405-407
16. Lubin B, Machlin LJ (1982) Vitamin E: biochemical, hematological and clinical aspects. Ann N Y Acad Sci 393:1-506
17. Bicakci U, Tander B, Ariturk E, Aydin BK (2005) Effects of omeprazole and gentamicin on the biochemical and histopathological alternations of the hypoxia/reoxygenation induced intestinal injury in newborn rats. Pediatr Surg Int 21:800-805
18. Suzuki M, Mori M, Miura S, Suematsu M (1996) Omeprazole attenuates oxygen-derived free radical production from human neutrophils. Free Radic Biol Med 21:727-731
19. Wandall JH (1992) Effects of omeprazole on neutrophil chemotaxis, super oxide production, degranulation and translocation of cytochrome b-245. Gut 33:617-621
20. Biswas K, Bandyopatdhyay U, Chattopadyay I, Varadaraj A (2003) A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavening of hydroxyl radical. J Biol Chem 278:10993-11001
21. Gehanno P, Guedon C (1981) Inhibition of experimental esophageal lye strictures by penicillamine. Arch Otolaryngol 107:145-147
22. Okhawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxidase in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358
23. Beutler E, Duron O, Kelly BM (1963) Improved method for the determination of blood glutathione. J Lab Clin Med 61:882-888
24. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J. Biol Chem 193:265-275
25. Reddy KG, Enwemeka CS (1996) A simplified method for analysis of hydroxyproline in biological tissues. Clin Biochem 29:225-229
26. Miller MJS, McNeill H, Mullane KM (1988) SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis. Am J Physiol 255:556-565
27. Rangan U, Bulkley GB (1993) Prospects for treatment of free radical mediated tissue injury. Br Med Bull 49:700-718
28. Lodish H, Baltimore D, Berk A, ZIpsuky SL (1996) Molecular cell biology. 3rd edn. Scientific American Books, New York
29. Anderson ME (1985) Determination of glutathione and glutathione sulfide in biological samples. Methods Enzymol 113:548-555
30. Shukla A, Rasik A, Patnaik (1997) Depletion of reduced glutathione, ascorbic acid, vitamin E and antioxidant defence enzymes in healing cutaneous wound. Free Rad Res 26:93-101
31. White MJ, Heckler FR (1990) Oxygen free radicals and wound healing. Clin Plastic Surg 14:473-483
32. Frei B (1994) Reactive oxygen species and antioxidant vitamins: mechanisms of action. Am J Med 97:5-12
33. Okur H, KucukkaydIn M, Kose K (1995) Hypoxia- induced necrotizing enterocolitis in the immature rats. The role of lipid peroxidation and management by vitamin E. J Pediatr Surg 30:1416-1419
34. Smith C, Marks A, Lieberman M (2004) Mark's basic medical biochemistry: a clinical approach, 2nd edn. LWW Press, Chicago
35. Trelstad RL, Lawley KR, Holmes LB (1983) Nonenzymatic hydroxylations of proline and lysine reduced oxygen derivates. Nature 289:310-312