Total synthesis of the Strychnos alkaloid (+)-minfiensine: Tandem enantioselective intramolecular Heck-iminium ion cyclization

Journal of the American Chemical Society

Volumn 130, Issue 15, 2008, Pages 5368-5377

  Dounay, Amy B ^a,b   Humphreys, Philip G ^a   Overman, Larry E ^a   Wrobleski, Aaron D ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PFIZER INC   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTRAMOLECULAR CHEMISTRY; STRYCHNOS ALKALOID MINFIENSINE; TOTAL SYNTHESIS; VINCORINE;

ALKALI METAL COMPOUNDS; ASYMPTOTIC ANALYSIS; CYCLIZATION; ENANTIOMERS; ENANTIOSELECTIVITY; PURIFICATION; SYNTHESIS (CHEMICAL);

ION SOURCES;

1,2 CYCLOHEXANEDIONE; 1,2,3,4 TETRAHYDRO 9A,4A (IMINOETHANO) 9H CARBAZOLE; 3,4 DIHYDRO 9A,4A (IMINOETHANO) 9H CARBAZOLE; AKUAMMILINE ALKALOID; ALKALOID DERIVATIVE; ANISIDINE; ECHITAMINE; IMINE; IODINE DERIVATIVE; KETONE DERIVATIVE; MINFIENSINE; PALLADIUM; UNCLASSIFIED DRUG; VINCORINE;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMICAL REACTION; CYCLIZATION; ENANTIOSELECTIVITY; HECK REACTION; REACTION ANALYSIS; REDUCTION; STRYCHNOS; SYNTHESIS;

ALKALOIDS; CARBAZOLES; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; CYCLOPARAFFINS; EPOXY COMPOUNDS; IMINES; IONS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM; STRYCHNOS;

EID: 42149168996     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja800163v     Document Type: Article

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