Optimizing antibiotic selection in treating COPD exacerbations

International Journal of COPD

Volumn 3, Issue 1, 2008, Pages 31-44

  Siddiqi, Attiya ^a   Sethi, Sanjay ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Antibiotics; Bronchitis; COPD; Exacerbation

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; AZITHROMYCIN; BRONCHODILATING AGENT; CEFDINIR; CEFPODOXIME; CEFUROXIME; CEPHALOSPORIN; CLARITHROMYCIN; CORTICOSTEROID; COTRIMOXAZOLE; DOXYCYCLINE; GEMIFLOXACIN; KETOLIDE; LEVOFLOXACIN; MACROLIDE; MOXIFLOXACIN; OFLOXACIN; PLACEBO; PROCALCITONIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; STEROID; TELITHROMYCIN;

ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL PROTOCOL; CLINICAL TRIAL; DIARRHEA; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG COST; DRUG UTILIZATION; HUMAN; MICROORGANISM DETECTION; NONHUMAN; PATHOGENESIS; PATIENT SELECTION; PROGNOSIS; QUALITY OF LIFE; REVIEW; RISK FACTOR; SPUTUM ANALYSIS; SYMPTOMATOLOGY; VIRULENCE; VIRUS INFECTION;

ACUTE DISEASE; ANTI-BACTERIAL AGENTS; DYSPNEA; HUMANS; PATIENT SELECTION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY TRACT INFECTIONS; SPUTUM;

EID: 42149152128     PISSN: 11769106     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (74)

1. Aaron SD, Vandemheen KL, et al. 2003. Outpatient oral prednisone after emergency treatment of chronic obstructive pulmonary disease. N Engl J Med, 348:2618-25.
2. Adams SG, Melo J, et al. 2000. Antibiotics are associated with lower relapse rates in outpatients with acute exacerbations of COPD. Chest, 117:1345-52.
3. Allegra L, Blasi F, et al. 2001. Antibiotic treatment and baseline severity of disease in acute exacerbations of chronic bronchitis: a re-evaluation of previously published data of a placebo-controlled randomized study. Pulm Pharmacol Ther, 14:149-55.
4. Anthonisen NR, Manfreda J, et al. 1987. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann Intern Med, 106:196-204.
5. Anzueto A, Rizzo JA, et al. 1999. The infection-free interval: its use in evaluating antimicrobial treatment of acute exacerbation of chronic bronchitis. Clin Infect Dis, 28:1344-5.
6. Bach PB, Brown C, et al. 2001. Management of acute exacerbations of chronic obstructive pulmonary disease: a summary and appraisal of published evidence. Ann Intern Med, 134:600-20.
7. Ball P, Harris JM, et al. 1995. Acute infective exacerbations of chronic bronchitis. QJMed, 88:61-8.
8. Balter MS, La Forge J, et al. 2003. Canadian guidelines for the management of acute exacerbations of chronic bronchitis. Can Respir J, 10(Suppl B):3B-32B.
9. Bhushan R, Kirkham C, et al. 1997. Antigenic characterization and analysis of the human immune response to outer membrane protein E of Branhamella catarrhalis. Infect Immun, 65:2668-75.
10. Burrows B, Earle RH. 1969. Course and prognosis of chronic obstructive lung disease. A prospective study of 200 patients. N Engl J Med, 280:397-404.
11. Calverley PM, Anderson JA, et al. 2007. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med, 356:775-89.
12. Celli BR, MacNee W. 2004. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J, 23:932-46.
13. Chin CL, Manzel LJ, et al. 2005. Haemophilus influenzae from patients with chronic obstructive pulmonary disease exacerbation induce more inflammation than colonizers. Am J Respir Crit Care Med, 172:85-91.
14. Dev D, Wallace E, et al. 1998. Value of C-reactive protein measurements in exacerbations of chronic obstructive pulmonary disease. Respir Med, 92:664-7.
15. Devalia JL, Rusznak C, et al. 1994. Effect of nitrogen dioxide and sulphur dioxide on airway response of mild asthmatic patients to allergen inhalation. Lancet, 344:1668-71.
16. Dewan NA, Rafique S, et al. 2000. Acute exacerbation of COPD: factors associated with poor treatment outcome. Chest, 117:662-71.
17. Donaldson GC, Seemungal TA, et al. 2002. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax, 57:847-52.
18. Eldika N, Sethi S. 2006. Role of nontypeable Haemophilus influenzae in exacerbations and progression of chronic obstructive pulmonary disease. Curr Opin Pulm Med, 12:118-24.
19. Falsey AR, Hennessey PA, et al. 2005. Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med, 352:1749-59.
20. Garcia-Aymerich J, Tobias A, et al. 2000. Air pollution and mortality in a cohort of patients with chronic obstructive pulmonary disease: a time series analysis. J Epidemiol Community Health, 54:73-4.
21. [GOLD] Global Initiative for Obstructive Lung Disease. 2007. Global Initiative for Obstructive Lung Disease [online]. Accessed on July 12, 2007. URL: http://www.goldcopd.com.
22. Groenewegen KH, Schols AM, et al. 2003. Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD. Chest, 124:459-67.
23. Heckerling PS. 1986. The need for chest roentgenograms in adults with acute respiratory illness. Arch Intern Med, 146:1321-4.
24. Hiltke TJ, Sethi S, et al. 2002. Sequence stability of the gene encoding outer membrane protein P2 of nontypeable Haemophilus influenzae in the human respiratory tract. J Infect Dis, 185:627-31.
25. Hirschmann JV. 2000. Do bacteria cause exacerbations of COPD? Chest, 118:193-203.
26. Hurst JR, Donaldson GC, et al. 2006. Use of plasma biomarkers at exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 174:867-74.
27. Johnston SL, Papi A, et al. 1998. Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium. J Immunol, 160:6172-81.
28. Kanner R, Anthonisen NR, et al. 2001. Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study. Am J Respir Crit Care Med, 164:358-64.
29. Kjaergard LL, Larsen FO, et al. 1996. Basophil-bound IgE and serum IgE directed against Haemophilus influenzae and Streptococcus pneumoniae in patients with chronic bronchitis during acute exacerbations. APMIS, 104:61-7.
30. Mandell LA, Bartlett JG, et al. 2003. Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults. Clin Infect Dis, 37:1405-33.
31. Martinez FJ, Curtis JL. 2007. Procalcitonin-guided antibiotic therapy in COPD exacerbations: closer but not quite there. Chest, 131:1-2.
32. Miravitlles M, Murio C, et al. 2001. Factors associated with relapse after ambulatory treatment of acute exacerbations of chronic bronchitis. DAFNE Study Group. Eur Respir J, 17:928-33.
33. Miravitlles M, Murio C, et al. 2002. Pharmacoeconomic evaluation of acute exacerbations of chronic bronchitis and COPD. Chest, 121:1449-55.
34. Miravitlles M, Ros F, et al. 2001. The efficacy of moxifloxacin in acute exacerbations of chronic bronchitis: a Spanish physician and patient experience. Int J Clin Pract, 55:437-41.
35. Murphy TF, Brauer AL, et al. 2005. Moraxella catarrhalis in chronic obstructive pulmonary disease: burden of disease and immune response. Am J Respir Crit Care Med, 172:195-9.
36. Murphy TF, Sethi S, et al. 2000. The role of bacteria in exacerbations of COPD. A constructive view. Chest, 118:204-9.
37. NHLBI. 2003. Chronic Obstructive Pulmonary Disease Data Fact Sheet, NIH Publication 03-5229.
38. Nouira S, Marghli S, et al. 2001. Once daily oral ofloxacin in chronic obstructive pulmonary disease exacerbation requiring mechanical ventilation: a randomised placebo-controlled trial. Lancet, 358:2020-5.
39. Obaji A, Sethi S. 2001. Acute exacerbations of chronic bronchitis. What role for the new fluoroquinolones? Drugs Aging, 18:1-11.
40. Ohtoshi T, Takizawa H, et al. 1998. Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro. J Allergy Clin Immunol, 101(6 Pt 1):778-85.
41. Pinto-Plata VM, Livnat G, et al. 2007. Systemic cytokines, clinical and physiological changes in patients hospitalized for exacerbation of COPD. Chest, 131:37-43.
42. Ram FS, Rodriguez-Roisin R, et al. 2006. Antibiotics for exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 2:CD004403.
43. Rodriguez-Roisin R. 2000. Toward a consensus definition for COPD exacerbations. Chest, 117(5 Suppl 2):398S-401S.
44. Rudell B, Blomberg A, et al. 1999. Bronchoalveolar inflammation after exposure to diesel exhaust: comparison between unfiltered and particle trap filtered exhaust. Occup Environ Med, 56:527-34.
45. Saint S, Bent S, et al. 1995. Antibiotics in chronic obstructive pulmonary disease exacerbations. A meta-analysis. JAMA, 273:957-96.
46. Seemungal T, Harper-Owen R, et al. 2001. Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 164:1618-23.
47. Seemungal TAR, Donaldson GC, et al. 1998. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 157:1418-22.
48. Sethi S. 2000. Infectious etiology of acute exacerbations of chronic bronchitis. Chest, 117:380S-385S.
49. Sethi S. 2002. Acute exacerbations of COPD: A "multipronged" approach. J Respir Dis, 23:217-55.
50. Sethi S. 2004a. Bacteria in exacerbations of chronic obstructive pulmonary disease. Phenomenon or epiphenomenon? Proc Am Thorac Soc, 1:109-14.
51. Sethi S. 2004b. New developments in the pathogenesis of acute exacerbations of chronic obstructive pulmonary disease. Curr Opin Infect Dis, 17:113-19.
52. Sethi S, Evans N, et al. 2002. Acquisition of a new bacterial strain and occurrence of exacerbations of chronic obstructive pulmonary disease. N Engl J Med, 347:465-71.
53. Sethi S, Murphy TF. 2004. Acute exacerbations of chronic bronchitis: new developments concerning microbiology and pathophysiology - impact on approaches to risk stratification and therapy. Infect Dis Clin North Am, 18:861-82, ix.
54. Sethi S, Murphy TF, et al. 2006. Antibiotic exposure in COPD and the development of penicillin and erythromycin resistance in Streptococcus pneumoniae. ICAAC, San Francisco CA, September 2006.
55. Sethi S, Muscarella K, et al. 2000. Airway inflammation and etiology of acute exacerbations of chronic bronchitis. Chest, 118:1557-65.
56. Sethi S, Wrona C, et al. 2004. Strain specific immune response to Haemophilus influenzae in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 169:448-53.
57. Sinus and Allergy Health P. 2004. Antimicrobial treatment guidelines for acute bacterial rhinosinusitis 2004. Otolaryngol Head Neck Surg, 130:1-45.
58. Soler N, Agusti C, et al. 2007. Bronchoscopic validation of the significance of sputum purulence in severe exacerbations of chronic obstructive pulmonary disease. Thorax, 62:29-35.
59. Soler N, Torres A, et al. 1998. Bronchial microbial patterns in severe exacerbations of chronic obstructive pulmonary disease (COPD) requiring mechanical ventilation. Am J Respir Crit Care Med, 157:1498-505.
60. Spencer S, Calverley PMA, et al. 2001. Health status deterioration in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 163:122-8.
61. Spencer S, Jones PW. 2003. Time course of recovery of health status following an infective exacerbation of chronic bronchitis. Thorax, 58:589-93.
62. Stockley RA, O'Brien C, et al. 2000. Relationship of sputum color to nature and outpatient managment of acute exacerbations of COPD. Chest, 117:1638-45.
63. Stolz D, Christ-Crain M, et al. 2007. Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy. Chest, 131:9-19.
64. Sunyer J, Saez M, et al. 1993. Air pollution and emergency room admissions for chronic obstructive pulmonary disease: a 5-year study. Am J Epidemiol, 137:701-5.
65. Sunyer J, Schwartz J, et al. 2000. Patients with chronic obstructive pulmonary disease are at increased risk of death associated with urban particle air pollution: a case-crossover analysis. Am J Epidemiol, 151:50-6.
66. Vanderkooi OG, Low DE, et al. 2005. Predicting antimicrobial resistance in invasive pneumococcal infections. Clin Infect Dis, 40:1288-97.
67. Veeramachaneni SB, Sethi S. 2006. Pathogenesis of bacterial exacerbations of COPD. J Chronic Obstructive Pul Dis, 3:109-15.
68. Wedzicha JA, Seemungal TA, et al. 2000. Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevations of plasma fibrinogen and serum IL-6 levels. Thromb Haemost, 84:210-15.
69. White AJ, Gompertz S, et al. 2003. Resolution of bronchial inflammation is related to bacterial eradication following treatment of exacerbations of chronic bronchitis. Thorax, 58:680-5.
70. White AJ, Gompertz S, et al. 2003. Chronic obstructive pulmonary disease. 6: The aetiology of exacerbations of chronic obstructive pulmonary disease. Thorax, 58:73-80.
71. Wilson R, Allegra L, et al. 2004. Short-term and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitis. Chest, 125:953-64.
72. Wilson R, Jones P, et al. 2006. Antibiotic treatment and factors influencing short and long term outcomes of acute exacerbations of chronic bronchitis. Thorax, 61:337-42.
73. Wilson R, Schentag JJ, et al. 2002. A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes. Clin Ther, 24:639-52.
74. Wood-Baker RR, Gibson PG, et al. 2005. Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 1:CD001288.