Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand

Immunology

Volumn 124, Issue 1, 2008, Pages 33-41

  Ebert, Ellen C ^a,b   Groh, Veronika ^c  

^a UMDNJ Robert Wood Johnson Medical School ^*  (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Colonic adenocarcinoma; Cytotoxicity; Intraepithelial lymphocytes; Major histocompatibility complex class I chain related protein; NKG2D

Indexed keywords

BINDING PROTEIN; FAS LIGAND; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I CHAIN RELATED PROTEIN; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; CD8+ T LYMPHOCYTE; CELL INTERACTION; COLON CANCER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOLYSIS; CYTOTOXICITY; EPITHELIUM TUMOR; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTESTINE EPITHELIUM CELL; MUCOSAL IMMUNITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; TUMOR IMMUNITY;

ADENOCARCINOMA; CELLS, CULTURED; COCULTURE TECHNIQUES; COLONIC NEOPLASMS; CYTOTOXICITY, IMMUNOLOGIC; FAS LIGAND PROTEIN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HT29 CELLS; HUMANS; INTERFERON TYPE II; INTESTINAL MUCOSA; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42149143633     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2007.02656.x     Document Type: Article

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