메뉴 건너뛰기




Volumn 263, Issue 5, 2008, Pages 558-571

The periodontal pathogen Porphyromonas gingivalis cleaves apoB-100 and increases the expression of apoM in LDL in whole blood leading to cell proliferation

Author keywords

Atherosclerosis; Growth factors; Infection; Inflammation; Lipoproteins

Indexed keywords

APOLIPOPROTEIN B100; APOLIPOPROTEIN M; GINGIPAIN R; LOW DENSITY LIPOPROTEIN; REACTIVE OXYGEN METABOLITE;

EID: 42149133781     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2007.01917.x     Document Type: Article
Times cited : (44)

References (63)
  • 1
    • 0031988026 scopus 로고    scopus 로고
    • Oral pathogens: From dental plaque to cardiac disease
    • Meyer D, Fives-Taylor P. Oral pathogens: from dental plaque to cardiac disease. Curr Opin Microbiol 1998 1 : 88 95.
    • (1998) Curr Opin Microbiol , vol.1 , pp. 88-95
    • Meyer, D.1    Fives-Taylor, P.2
  • 2
    • 0031936879 scopus 로고    scopus 로고
    • Periodontal disease and risk for myocardial infection and cardiovascular disease
    • Genco RJ. Periodontal disease and risk for myocardial infection and cardiovascular disease. Cardiovasc Rev Rep 1998 19 : 34 40.
    • (1998) Cardiovasc Rev Rep , vol.19 , pp. 34-40
    • Genco, R.J.1
  • 3
    • 0035571671 scopus 로고    scopus 로고
    • Relationship of periodontal disease to carotid artery intima-media wall thickness: The atherosclerosis risk in communities (ARIC) study
    • Beck JD, Elter JR, Heiss G, Couper D, Mauriello SM, Offenbacher S. Relationship of periodontal disease to carotid artery intima-media wall thickness: the atherosclerosis risk in communities (ARIC) study. Arterioscler Thromb Vasc Biol 2001 21 : 1816 22.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1816-22
    • Beck, J.D.1    Elter, J.R.2    Heiss, G.3    Couper, D.4    Mauriello, S.M.5    Offenbacher, S.6
  • 4
    • 0026847143 scopus 로고
    • The bacterial etiology of destructive periodontal disease: Current concepts
    • Socransky SS, Haffajee AD. The bacterial etiology of destructive periodontal disease: current concepts. J Periodontol 1992 63 : 322 31.
    • (1992) J Periodontol , vol.63 , pp. 322-31
    • Socransky, S.S.1    Haffajee, A.D.2
  • 8
    • 0034040505 scopus 로고    scopus 로고
    • Reactive oxygen species: A potential role in the pathogenesis of periodontal diseases
    • Waddington RJ, Moseley R, Embery G. Reactive oxygen species: a potential role in the pathogenesis of periodontal diseases. Oral Dis 2000 6 : 138 51.
    • (2000) Oral Dis , vol.6 , pp. 138-51
    • Waddington, R.J.1    Moseley, R.2    Embery, G.3
  • 9
    • 24344457983 scopus 로고    scopus 로고
    • Lipid peroxidation: A possible role in the induction and progression of chronic periodontitis
    • Tsai CC, Chen HS, Chen SL et al. Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis. J Periodontal Res 2005 40 : 378 84.
    • (2005) J Periodontal Res , vol.40 , pp. 378-84
    • Tsai, C.C.1    Chen, H.S.2    Chen, S.L.3
  • 10
    • 0000663262 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989 321 : 1196 7.
    • (1989) N Engl J Med , vol.321 , pp. 1196-7
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 11
    • 0036253437 scopus 로고    scopus 로고
    • Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: The role of vitamin C
    • Carr A, Frei B. Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C. Biol Chem 2002 383 : 627 36.
    • (2002) Biol Chem , vol.383 , pp. 627-36
    • Carr, A.1    Frei, B.2
  • 12
    • 0028905404 scopus 로고
    • Lipid peroxidation by activated platelets: A possible link between thrombosis and atherogenesis
    • Gorog P, Kovacs I. Lipid peroxidation by activated platelets: a possible link between thrombosis and atherogenesis. Atherosclerosis 1995 115 : 121 8.
    • (1995) Atherosclerosis , vol.115 , pp. 121-8
    • Gorog, P.1    Kovacs, I.2
  • 13
    • 0029883764 scopus 로고    scopus 로고
    • The role of oxidized lipoproteins in atherogenesis
    • Berliner JA, Hencke JW. The role of oxidized lipoproteins in atherogenesis. Free Radic Biol Med 1996 20 : 707 27.
    • (1996) Free Radic Biol Med , vol.20 , pp. 707-27
    • Berliner, J.A.1    Hencke, J.W.2
  • 14
    • 33644543347 scopus 로고    scopus 로고
    • Impact of oxidized low density lipoprotein on vascular cells
    • Galle J, Hansen-Hagge T, Wanner C, Seibold S. Impact of oxidized low density lipoprotein on vascular cells. Atherosclerosis 2006 185 : 219 26.
    • (2006) Atherosclerosis , vol.185 , pp. 219-26
    • Galle, J.1    Hansen-Hagge, T.2    Wanner, C.3    Seibold, S.4
  • 15
  • 16
    • 23744464765 scopus 로고    scopus 로고
    • Chlamydia pneumoniae induces nitric oxide synthase and lipoxygenase-dependent production of reactive oxygen species in platelets
    • Kälvegren H, Bylin H, Leanderson P, Richter A, Grenegård M, Bengtsson T. Chlamydia pneumoniae induces nitric oxide synthase and lipoxygenase-dependent production of reactive oxygen species in platelets. Thromb Haemost 2005 94 : 327 35.
    • (2005) Thromb Haemost , vol.94 , pp. 327-35
    • Kälvegren, H.1    Bylin, H.2    Leanderson, P.3    Richter, A.4    Grenegård, M.5    Bengtsson, T.6
  • 17
    • 0023833209 scopus 로고
    • Presence of a modified low density lipoprotein in humans
    • Avogaro P, Bon GB, Cazzolato G. Presence of a modified low density lipoprotein in humans. Arteriosclerosis 1988 8 : 79 87.
    • (1988) Arteriosclerosis , vol.8 , pp. 79-87
    • Avogaro, P.1    Bon, G.B.2    Cazzolato, G.3
  • 18
    • 0029555988 scopus 로고
    • Naturally occurring modified low density lipoproteins are similar if not identical: More electronegative and desialylated lipoprotein subfractions
    • Tertov VV, Bittolo-Bon G, Sobenin IA, Cazzolato G, Orekhov AN, Avogaro P. Naturally occurring modified low density lipoproteins are similar if not identical: more electronegative and desialylated lipoprotein subfractions. Exp Mol Pathol 1995 62 : 166 72.
    • (1995) Exp Mol Pathol , vol.62 , pp. 166-72
    • Tertov, V.V.1    Bittolo-Bon, G.2    Sobenin, I.A.3    Cazzolato, G.4    Orekhov, A.N.5    Avogaro, P.6
  • 19
    • 0029741926 scopus 로고    scopus 로고
    • Oxidation of plasma low-density lipoprotein accelerates its accumulation and degradation in the arterial wall in vivo
    • Juul K, Nielsen LB, Munkholm K, Stender S, Nordestgaard BG. Oxidation of plasma low-density lipoprotein accelerates its accumulation and degradation in the arterial wall in vivo. Circulation 1996 94 : 1698 704.
    • (1996) Circulation , vol.94 , pp. 1698-704
    • Juul, K.1    Nielsen, L.B.2    Munkholm, K.3    Stender, S.4    Nordestgaard, B.G.5
  • 20
    • 0000762116 scopus 로고
    • The platelet as an inflammatory cell in periodontal diseases
    • In: Genco, R.J., Hamada, S., Lehrer, J.R., McGhee, J.R., Mergenhagen, S., eds. Washington, DC: ASM Press
    • Herzberg MC, MacFarlane GD, Liu P, Erickson PR. The platelet as an inflammatory cell in periodontal diseases. In : Genco RJ, Hamada S, Lehrer JR, McGhee JR, Mergenhagen S, eds. Molecular Pathogenesis of Periodontal Diseases. Washington, DC : ASM Press, 1994 247 55.
    • (1994) Molecular Pathogenesis of Periodontal Diseases. , pp. 247-55
    • Herzberg, M.C.1    MacFarlane, G.D.2    Liu, P.3    Erickson, P.R.4
  • 21
    • 0036189845 scopus 로고    scopus 로고
    • Aggregation of human platelets by gingipain-R from Porphyromonas gingivalis cells and membrane vesicles
    • Pham K, Feik D, Hammond BF, Rams TE, Whitaker EJ. Aggregation of human platelets by gingipain-R from Porphyromonas gingivalis cells and membrane vesicles. Platelets 2002 13 : 21 30.
    • (2002) Platelets , vol.13 , pp. 21-30
    • Pham, K.1    Feik, D.2    Hammond, B.F.3    Rams, T.E.4    Whitaker, E.J.5
  • 22
    • 0642335286 scopus 로고    scopus 로고
    • Intracellular production and extracellular release of oxygen radicals by PMNs and oxidative stress on PMNs during phagocytosis of periodontopathic bacteria
    • Katsuragi H, Ohtake M, Kurasawa I, Saito K. Intracellular production and extracellular release of oxygen radicals by PMNs and oxidative stress on PMNs during phagocytosis of periodontopathic bacteria. Odontology 2003 91 : 13 8.
    • (2003) Odontology , vol.91 , pp. 13-8
    • Katsuragi, H.1    Ohtake, M.2    Kurasawa, I.3    Saito, K.4
  • 23
    • 0034036648 scopus 로고    scopus 로고
    • Modified LDL - Trigger of atherosclerosis and inflammation in the arterial intima
    • Pentikäinen MO, Öörni K, Ala-Korpela M, Kovanen PT. Modified LDL - trigger of atherosclerosis and inflammation in the arterial intima. J Intern Med 2000 247 : 359 70.
    • (2000) J Intern Med , vol.247 , pp. 359-70
    • Pentikäinen, M.O.1    Öörni, K.2    Ala-Korpela, M.3    Kovanen, P.T.4
  • 24
    • 0031894810 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesion
    • Torzewski M, Klouche M, Hock J et al. Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesion. Arterioscler Thromb Vasc Biol 1998 18 : 369 78.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 369-78
    • Torzewski, M.1    Klouche, M.2    Hock, J.3
  • 25
    • 0033575199 scopus 로고    scopus 로고
    • Different apolipoprotein B breakdown patterns in models of oxidized low density lipoprotein
    • Viita H, Narvanen O, Yla-Herttuala S. Different apolipoprotein B breakdown patterns in models of oxidized low density lipoprotein. Life Sci 1999 65 : 783 93.
    • (1999) Life Sci , vol.65 , pp. 783-93
    • Viita, H.1    Narvanen, O.2    Yla-Herttuala, S.3
  • 27
    • 13844306306 scopus 로고    scopus 로고
    • Lipoproteomics I: Mapping of proteins in low-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry
    • Karlsson H, Leanderson P, Tagesson C, Lindahl M. Lipoproteomics I: mapping of proteins in low-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry. Proteomics 2005 5 : 551 65.
    • (2005) Proteomics , vol.5 , pp. 551-65
    • Karlsson, H.1    Leanderson, P.2    Tagesson, C.3    Lindahl, M.4
  • 28
    • 17044423032 scopus 로고    scopus 로고
    • Lipoproteomics II: Mapping of proteins in high-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry
    • Karlsson H, Leanderson P, Tagesson C, Lindahl M. Lipoproteomics II: mapping of proteins in high-density lipoprotein using two-dimensional gel electrophoresis and mass spectrometry. Proteomics 2005 5 : 1431 45.
    • (2005) Proteomics , vol.5 , pp. 1431-45
    • Karlsson, H.1    Leanderson, P.2    Tagesson, C.3    Lindahl, M.4
  • 29
    • 0032518227 scopus 로고    scopus 로고
    • Inhibition of mammalian 15-lipoxygenase-dependent lipid peroxidation in low-density lipoprotein by quercetin and quercetin monoglycosides
    • Da Silva EL, Tsushida T, Terao J. Inhibition of mammalian 15-lipoxygenase-dependent lipid peroxidation in low-density lipoprotein by quercetin and quercetin monoglycosides. Arch Biochem Biophys 1998 349 : 313 20.
    • (1998) Arch Biochem Biophys , vol.349 , pp. 313-20
    • Da Silva, E.L.1    Tsushida, T.2    Terao, J.3
  • 30
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976 72 : 248 54.
    • (1976) Anal Biochem , vol.72 , pp. 248-54
    • Bradford, M.M.1
  • 32
    • 0032428443 scopus 로고    scopus 로고
    • Protein patterns of human nasal and bronchoalveolar lavage fluids analyzed with two-dimensional gel electrophoresis
    • Lindahl M, Stahlbom B, Svartz J, Tagesson C. Protein patterns of human nasal and bronchoalveolar lavage fluids analyzed with two-dimensional gel electrophoresis. Electrophoresis 1998 19 : 3222 9.
    • (1998) Electrophoresis , vol.19 , pp. 3222-9
    • Lindahl, M.1    Stahlbom, B.2    Svartz, J.3    Tagesson, C.4
  • 33
    • 0034095972 scopus 로고    scopus 로고
    • The current state of two-dimensional electrophoresis with immobilized pH gradients
    • Görg A, Obermaier C, Boguth G et al. The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 2000 21 : 1037 53.
    • (2000) Electrophoresis , vol.21 , pp. 1037-53
    • Görg, A.1    Obermaier, C.2    Boguth, G.3
  • 34
    • 0029927505 scopus 로고    scopus 로고
    • Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
    • Shevchenko A, Wilm M, Vorm O, Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 1996 68 : 850 8.
    • (1996) Anal Chem , vol.68 , pp. 850-8
    • Shevchenko, A.1    Wilm, M.2    Vorm, O.3    Mann, M.4
  • 35
    • 33751240080 scopus 로고    scopus 로고
    • Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase
    • Berg C, Hammarstrom S, Herbertsson H et al. Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase. Thromb Haemost 2006 96 : 652 9.
    • (2006) Thromb Haemost , vol.96 , pp. 652-9
    • Berg, C.1    Hammarstrom, S.2    Herbertsson, H.3
  • 36
    • 1542547941 scopus 로고    scopus 로고
    • Interaction of Porphyromonas gingivalis with low-density lipoproteins: Implications for a role for periodontitis in atherosclerosis
    • Miyakawa H, Honma K, Qi M, Kuramitsu HK. Interaction of Porphyromonas gingivalis with low-density lipoproteins: implications for a role for periodontitis in atherosclerosis. J Periodontal Res 2004 39 : 1 9.
    • (2004) J Periodontal Res , vol.39 , pp. 1-9
    • Miyakawa, H.1    Honma, K.2    Qi, M.3    Kuramitsu, H.K.4
  • 37
    • 0025911829 scopus 로고
    • Metal-catalyzed oxidation of proteins. Physiological consequences
    • Stadtman ER, Oliver CN. Metal-catalyzed oxidation of proteins. Physiological consequences. J Biol Chem 1991 266 : 2005 8.
    • (1991) J Biol Chem , vol.266 , pp. 2005-8
    • Stadtman, E.R.1    Oliver, C.N.2
  • 38
    • 0029328311 scopus 로고
    • Spectrophotometric method for determination of carbonyls in oxidatively modified apolipoprotein B of human low-density lipoproteins
    • Yan LJ, Traber MG, Packer L. Spectrophotometric method for determination of carbonyls in oxidatively modified apolipoprotein B of human low-density lipoproteins. Anal Biochem 1995 228 : 349 51.
    • (1995) Anal Biochem , vol.228 , pp. 349-51
    • Yan, L.J.1    Traber, M.G.2    Packer, L.3
  • 39
    • 0035877969 scopus 로고    scopus 로고
    • Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: A new trait in microbial pathogenicity
    • Lourbakos A, Yuan YP, Jenkins AL et al. Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity. Blood 2001 97 : 3790 7.
    • (2001) Blood , vol.97 , pp. 3790-7
    • Lourbakos, A.1    Yuan, Y.P.2    Jenkins, A.L.3
  • 40
    • 0032508557 scopus 로고    scopus 로고
    • Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis
    • Lourbakos A, Chinni C, Thompson P et al. Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis. FEBS Lett 1998 435 : 45 8.
    • (1998) FEBS Lett , vol.435 , pp. 45-8
    • Lourbakos, A.1    Chinni, C.2    Thompson, P.3
  • 41
    • 33644820657 scopus 로고    scopus 로고
    • Porphyromonas gingivalis-induced inflammatory mediator profile in an ex vivo human whole blood model
    • Bodet C, Chandad F, Grenier D. Porphyromonas gingivalis-induced inflammatory mediator profile in an ex vivo human whole blood model. Clin Exp Immunol 2006 143 : 50 7.
    • (2006) Clin Exp Immunol , vol.143 , pp. 50-7
    • Bodet, C.1    Chandad, F.2    Grenier, D.3
  • 42
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev 2004 84 : 1381 478.
    • (2004) Physiol Rev , vol.84 , pp. 1381-478
    • Stocker, R.1    Keaney Jr., J.F.2
  • 43
    • 7244220166 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein in plasma is a prognostic marker of subclinical atherosclerosis development in clinically healthy men
    • Wallenfeldt K, Fagerberg B, Wikstrand J, Hulthe J. Oxidized low-density lipoprotein in plasma is a prognostic marker of subclinical atherosclerosis development in clinically healthy men. J Intern Med 2004 256 : 413 20.
    • (2004) J Intern Med , vol.256 , pp. 413-20
    • Wallenfeldt, K.1    Fagerberg, B.2    Wikstrand, J.3    Hulthe, J.4
  • 45
    • 0023221153 scopus 로고
    • Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products
    • Steinbrecher UP. Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products. J Biol Chem 1987 262 : 3603 8.
    • (1987) J Biol Chem , vol.262 , pp. 3603-8
    • Steinbrecher, U.P.1
  • 46
    • 33644832991 scopus 로고    scopus 로고
    • Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins
    • Brown BE, Mahroof FM, Cook NL, Van Reyk DM, Davies MJ. Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins. Diabetologia 2006 49 : 775 83.
    • (2006) Diabetologia , vol.49 , pp. 775-83
    • Brown, B.E.1    Mahroof, F.M.2    Cook, N.L.3    Van Reyk, D.M.4    Davies, M.J.5
  • 47
    • 0034756199 scopus 로고    scopus 로고
    • Oxidative events caused degradation of apo B-100 but not of apo[a] and facilitate enzymatic cleavage of both proteins
    • Edelstein C, Nakajima K, Pfaffinger D, Scanu AM. Oxidative events caused degradation of apo B-100 but not of apo[a] and facilitate enzymatic cleavage of both proteins. J Lipid Res 2001 42 : 1664 70.
    • (2001) J Lipid Res , vol.42 , pp. 1664-70
    • Edelstein, C.1    Nakajima, K.2    Pfaffinger, D.3    Scanu, A.M.4
  • 48
    • 33846070773 scopus 로고    scopus 로고
    • Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure
    • Hashimoto M, Kadowaki T, Tsukuba T, Yamamoto K. Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure. J Biochem (Tokyo) 2006 140 : 713 23.
    • (2006) J Biochem (Tokyo) , vol.140 , pp. 713-23
    • Hashimoto, M.1    Kadowaki, T.2    Tsukuba, T.3    Yamamoto, K.4
  • 49
    • 0039136346 scopus 로고    scopus 로고
    • A novel human apolipoprotein (apoM)
    • Xu N, Dahlbäck B. A novel human apolipoprotein (apoM). J Biol Chem 1999 274 : 31286 90.
    • (1999) J Biol Chem , vol.274 , pp. 31286-90
    • Xu, N.1    Dahlbäck, B.2
  • 50
    • 33750124981 scopus 로고    scopus 로고
    • Characterization of apolipoprotein M isoforms in low-density lipoprotein
    • Karlsson H, Lindqvist H, Tagesson C, Lindahl M. Characterization of apolipoprotein M isoforms in low-density lipoprotein. J Proteome Res 2006 5 : 2685 90.
    • (2006) J Proteome Res , vol.5 , pp. 2685-90
    • Karlsson, H.1    Lindqvist, H.2    Tagesson, C.3    Lindahl, M.4
  • 51
    • 0035875801 scopus 로고    scopus 로고
    • Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis
    • Duan J, Dahlback B, Villoutreix BO. Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis. FEBS Lett 2001 499 : 127 32.
    • (2001) FEBS Lett , vol.499 , pp. 127-32
    • Duan, J.1    Dahlback, B.2    Villoutreix, B.O.3
  • 52
    • 0037219269 scopus 로고    scopus 로고
    • Specific tissue expression and cellular localization of human apolipoprotein M as determined by in situ hybridization
    • Zhang XY, Dong X, Zheng L et al. Specific tissue expression and cellular localization of human apolipoprotein M as determined by in situ hybridization. Acta Histochem 2003 105 : 67 72.
    • (2003) Acta Histochem , vol.105 , pp. 67-72
    • Zhang, X.Y.1    Dong, X.2    Zheng, L.3
  • 53
    • 0036293085 scopus 로고    scopus 로고
    • Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1alpha on the expression of apolipoprotein M in HepG2 cells
    • Xu N, Zhang XY, Dong X, Ekstrom U, Ye Q, Nilsson-Ehle P. Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1alpha on the expression of apolipoprotein M in HepG2 cells. Biochem Biophys Res Commun 2002 292 : 944 50.
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 944-50
    • Xu, N.1    Zhang, X.Y.2    Dong, X.3    Ekstrom, U.4    Ye, Q.5    Nilsson-Ehle, P.6
  • 55
    • 19444375752 scopus 로고    scopus 로고
    • Leptin inhibits apolipoprotein M transcription and secretion in human hepatoma cell line, HepG2 cells
    • Luo G, Hurtig M, Zhang X, Nilsson-Ehle P, Xu N. Leptin inhibits apolipoprotein M transcription and secretion in human hepatoma cell line, HepG2 cells. Biochim Biophys Acta 2005 1734 : 198 202.
    • (2005) Biochim Biophys Acta , vol.1734 , pp. 198-202
    • Luo, G.1    Hurtig, M.2    Zhang, X.3    Nilsson-Ehle, P.4    Xu, N.5
  • 56
    • 17644393111 scopus 로고    scopus 로고
    • Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis
    • Wolfrum C, Poy MN, Stoffel M. Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis. Nat Med 2005 11 : 418 22.
    • (2005) Nat Med , vol.11 , pp. 418-22
    • Wolfrum, C.1    Poy, M.N.2    Stoffel, M.3
  • 58
    • 3042560032 scopus 로고    scopus 로고
    • Characterization of apoM in normal and genetically modified mice
    • Faber K, Axler O, Dahlback B, Nielsen LB. Characterization of apoM in normal and genetically modified mice. J Lipid Res 2004 45 : 1272 8.
    • (2004) J Lipid Res , vol.45 , pp. 1272-8
    • Faber, K.1    Axler, O.2    Dahlback, B.3    Nielsen, L.B.4
  • 60
    • 0034681941 scopus 로고    scopus 로고
    • Enzymatically degraded, nonoxidized LDL induces human vascular smooth muscle cell activation, foam cell transformation, and proliferation
    • Klouche M, Rose-John S, Schmiedt W, Bhakdi S. Enzymatically degraded, nonoxidized LDL induces human vascular smooth muscle cell activation, foam cell transformation, and proliferation. Circulation 2000 101 : 1799 805.
    • (2000) Circulation , vol.101 , pp. 1799-805
    • Klouche, M.1    Rose-John, S.2    Schmiedt, W.3    Bhakdi, S.4
  • 61
    • 1842423306 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein retards the growth of proliferating cells by inhibiting nuclear translocation of cell cycle proteins
    • Zettler ME, Prociuk MA, Austria JA, Zhong G, Pierce GN. Oxidized low-density lipoprotein retards the growth of proliferating cells by inhibiting nuclear translocation of cell cycle proteins. Arterioscler Thromb Vasc Biol 2004 24 : 727 32.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 727-32
    • Zettler, M.E.1    Prociuk, M.A.2    Austria, J.A.3    Zhong, G.4    Pierce, G.N.5
  • 62
    • 0031833783 scopus 로고    scopus 로고
    • Esterified cholesterol accumulation induced by aggregated LDL uptake in human vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitors
    • Llorente-Cortes V, Martinez-Gonzalez J, Badimon L. Esterified cholesterol accumulation induced by aggregated LDL uptake in human vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitors. Arterioscler Thromb Vasc Biol 1998 18 : 738 46.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 738-46
    • Llorente-Cortes, V.1    Martinez-Gonzalez, J.2    Badimon, L.3
  • 63
    • 0028207078 scopus 로고
    • Apolipoprotein B of oxidized LDL accumulates in the lysosomes of macrophages
    • Mander EL, Dean RT, Stanley KK, Jessup W. Apolipoprotein B of oxidized LDL accumulates in the lysosomes of macrophages. Biochim Biophys Acta 1994 1212 : 80 92.
    • (1994) Biochim Biophys Acta , vol.1212 , pp. 80-92
    • Mander, E.L.1    Dean, R.T.2    Stanley, K.K.3    Jessup, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.