Human tissue factor pathway inhibitor-2 induces caspase-mediated apoptosis in a human fibrosarcoma cell line

Apoptosis

Volumn 13, Issue 5, 2008, Pages 702-715

  Kempaiah, Prakasha ^a   Kisiel, Walter ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

Apoptosis; Caspase activation; Proteinase inhibitors; TFPI 2; Tumors

Indexed keywords

ACRIDINE ORANGE; ARGININE; CASPASE; CASPASE 3; CASPASE 9; ETHIDIUM BROMIDE; LYSINE; PLACENTA PROTEIN 5; PROTEIN BAX; PROTEIN BCL 2; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR;

APOPTOSIS; ARTICLE; CANCER CELL; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG STABILITY; ENZYME ACTIVATION; FIBROSARCOMA; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MICROARRAY ANALYSIS; MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEINASE INHIBITION; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL LINE, TUMOR; COLONIC NEOPLASMS; DOWN-REGULATION; FIBROSARCOMA; FLOW CYTOMETRY; GLYCOPROTEINS; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; RNA, MESSENGER; UP-REGULATION; URINARY BLADDER NEOPLASMS;

EID: 42149123219     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0207-8     Document Type: Article

References (29)

1. Chand HS, Schmidt AE, Bajaj SP, Kisiel W (2004) Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2. J Biol Chem 279:17500-17507
2. Rao CN, Peavey CL, Liu YY, Lapiere JC, Woodley DT (1995) Partial characterization of matrix-associated serine protease inhibitors from human skin cells. J Invest Dermatol 104:379-383
3. Iino M, Foster DC, Kisiel W (1998) Quanti§fication and characterization of human endothelial cell-derived tissue factor pathway inhibitor-2. Arterioscler Thromb Vasc Biol 18:40-46
4. Herman MP, Sukhova GK, Kisiel W et al (2001) Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis. J Clin Invest 107:1117-1126
5. Sugiyama T, Ishii S, Yamamoto J et al (2002) cDNA macroarray analysis of gene expression in synoviocytes stimulated with TNFα. FEBS Lett 517:121-128
6. Chand HS, Du X, Ma D et al (2004) The effect of human tissue factor pathway inhibitor-2 on the growth and metastasis of fibrosarcoma tumors in athymic mice. Blood 103:1069-1077
7. Rao CN, Mohanam S, Puppala A, Rao JS (1999) Regulation of proMMP-1 and proMMP-3 activation by tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor. Biochem Biophys Res Commun 255:94-99
8. Izumi H, Takahashi C, Oh J, Noda M (2000) Tissue factor pathway inhibitor-2 suppresses the production of active matrix metalloproteinase-2 and is down-regulated in cells harboring activated ras oncogenes. FEBS Lett 481:31-36
9. Rao CN, Cook B, Liu Y et al (1998) HT-1080 fibrosarcoma cell matrix degradation and invasion are inhibited by the matrix-associated serine protease inhibitor TFPI-2/33 kDa MSPI. Int J Cancer 76:749-756
10. Kempaiah P, Chand HS, Kisiel W (2007) Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues. Mol Cancer 6:20
11. Konduri SD, Tasiou A, Chandrasekar N, Rao JS (2001) Overexpression of tissue factor pathway inhibitor-2 (TFPI-2), decreases the invasiveness of prostate cancer cells in vitro. Int J Oncol 18:127-131
12. Jin M, Udagawa K, Miyagi E et al (2001) Expression of serine proteinase inhibitor PP5/TFPI-2/MSPI decreases the invasive potential of human choriocarcinoma cells in vitro and in vivo. Gynecol Oncol 83:325-333
13. Yanamandra N, Kondraganti S, Gondi CS et al (2005) Recombinant adeno-associated virus (rAAV) expressing TFPI-2 inhibits invasion, angiogenesis and tumor growth in a human glioblastoma cell line. Int J Oncol 29:25-32
14. Kondraganti S, Gondi CS, Gujrati M et al (2006) Restoration of tissue factor pathway inhibitor inhibits invasion and tumor growth in vitro and in vivo in a malignant meningioma cell line. Int J Oncol 29:25-32
15. Ivanciu L, Gerard RD, Tang H, Lupu F, Lupu C (2007) Adenovirus-mediated expression of tissue factor pathway inhibitor-2 inhibits endothelial cell migration and angiogenesis. Arterioscler Thromb Vasc Biol 27:310-316
16. Tasiou A, Konduri SD, Yanamandra N et al (2001) A novel role of tissue factor pathway inhibitor-2 in apoptosis of malignant human gliomas. Int J Oncol 19:591-597
17. George J, Gondi CS, Dinh DH, Gujrati M, Rao JS (2007) Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis. Clin Cancer Res 13:3507-3517
18. Ribble D, Goldstein NB, Norris DA, Shellman YG (2005) A simple technique for quantifying apoptosis in 96-well plates. BMC Biotechnol 10:5-12
19. Jarvis DW, Kolesnick RN, Fornari FA, Traylor RS, Gewirtz DA, Grant S (1994) Induction of apoptotic DNA degradation and cell death by activation of the sphingomyelin pathway. Proc Natl Acad Sci USA 91:73-77
20. Baskin DS, Ngo H, Didenko VV (2003) Thimerosal induces DNA breaks, caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblasts. Toxicol Sci 74:361-368
21. Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM (1992) Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 148:2207-2216
22. Vermes IC, Haanen H, Steffens-Nakken C Reutelingsperger (1995) A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Meth 184:39-51
23. Konduri SD, Rao CN, Chandrasekar N et al (2001) A novel function of tissue factor pathway inhibitor-2 (TFPI-2) in human glioma invasion. Oncogene 20:6938-6945
24. Compton MM (1992) A biochemical hallmark of apoptosis: internucleosomal degradation of the genome. Cancer Metastasis Rev 11:105-119
25. Aggarwal BB, Shishodia S, Ashikawa K, Bharti AC (2002) The role of TNF and its family members in inflammation and cancer: lessons from gene deletion. Curr Drug Targets Inflamm Allergy 1:327-341
26. Kimura H, Gules I, Meguro T, Zhang JH (2003) Cytotoxicity of cytokines in cerebral microvascular endothelial cell. Brain Res 990:148-156
27. Hamuro T, Kamikubo Y, Nakahara Y, Miyamoto S, Funatsu A (1998) Human recombinant tissue factor pathway inhibitor induces apoptosis in cultured human endothelial cells. FEBS Lett 421:197-202
28. Lin YF, Zhang N, Guo HS et al (2007) Recombinant tissue factor pathway inhibitor induces apoptosis in cultured rat mesangial cells via its Kunitz-3 domain and C-terminal through inhibiting PI3-kinase/Akt pathway. Apoptosis 12:2163-2173
29. Wetzel M, Rosenberg GA, Cunningham LA (2003) Tissue inhibitor of metalloproteinases-3 and matrix metalloproteinase-3 regulate neuronal sensitivity to doxorubicin-induced apoptosis. Eur J Neurosci 18:1050-1060