Cellulose acetate microspheres as floating depot systems to increase gastric retention of antidiabetic drug: Formulation, characterization and in vitro-in vivo evaluation

Drug Development and Industrial Pharmacy

Volumn 34, Issue 4, 2008, Pages 349-354

  Choudhury, Pratim K ^a   Kar, Mousumi ^b   Chauhan, Chetan S ^c  

^a FIJI SCHOOL OF MEDICINE   (Fiji)

^b M L SUKHADIA UNIVERSITY   (India)

^c BN College of Pharmacy   (India)

Author keywords

Cellulose acetate; Floating microspheres; In vitro release; In vivo; Metformin hydrochloride

Indexed keywords

ANTIDIABETIC AGENT; CELLULOSE ACETATE; GLUCOSE; METFORMIN; MICROSPHERE; PHOSPHATE BUFFERED SALINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SCREENING; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROENCAPSULATION; MICROSCOPY; MOUSE; NONHUMAN; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; STOMACH ABSORPTION;

ANIMALS; BLOOD GLUCOSE; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIABETES MELLITUS; DRUG CARRIERS; GASTROINTESTINAL TRACT; HYPOGLYCEMIC AGENTS; LINEAR MODELS; MALE; METFORMIN; MICE; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE;

EID: 42049121455     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701542531     Document Type: Article

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