Evaluation of enteric matrix microspheres prepared by emulsion-solvent evaporation using scanning electron microscopy

Journal of Microencapsulation

Volumn 21, Issue 1, 2004, Pages 47-57

  Obeidat, W M ^a   Price, J C ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Butyrate; Cellulose acetate; Cellulose acetate phthalate; Dissolution kinetics; Microspheres; Scanning electron microscopy

Indexed keywords

CELLABURATE; CELLACEFATE; MICROSPHERE; POLYMER; SOLVENT; THEOPHYLLINE;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG FORMULATION; DRUG ISOLATION; DRUG RELEASE; DRUG SOLUBILITY; EMULSION; EVAPORATION; INTESTINE FLUID; SCANNING ELECTRON MICROSCOPY; SIMULATION; STOMACH JUICE; STOMACH PH;

CELLULOSE; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EMULSIONS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; SOLVENTS; THEOPHYLLINE;

EID: 0842346720     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652040310001619983     Document Type: Article

References (5)

1. Chiao, C. S. L. and Price, J. C., 1994, Effect of compression pressure on physical properties and dissolution characteristics of disintegrating tablets of propranolol microspheres. Journal of Microencapsulation, 11, 161-170.
2. Higuchi, T., 1963, Mechanism of sustained action medication, theoretical analysis of rate of release of solid drug dispersed in solid matrices. Journal of Pharmaceutical Sciences, 52, 145-149.
3. Obeidat, W. M. and Price, J. C., 2003. Viscosity of polymer solution phase and other factors controlling the dissolution of theophylline microspheres prepared by the emulsion-solvent evaporation method. Journal of Microencapsulation, 20, 57-65.
4. Sayed, H. A. M. and Price, J. C., 1986, Tablet properties and dissolution characteristics of compressed cellulose acetate butyrate microcapsules containing succinyl sulfathiazole. Drug Development and Industrial Pharmacy, 12, 577-587.
5. Stithit, S., Chen, W. and Price, J. C., 1998, Development and characterization of buoyant theophylline microspheres with near zero-order release kinetics. Journal of Microencapsulation, 15, 725-737.