Preparation of 1,8-Di-O-alkylaloe-emodins and 15-amino-, 15-thiocyano-, and 15-selenocyanochrysophanol derivatives from aloe-emodin and studying their cytotoxic effects

Chemical and Pharmaceutical Bulletin

Volumn 56, Issue 4, 2008, Pages 497-503

  Cui, Xing Ri ^a   Takahashi, Kazutoshi ^a   Shimamura, Takeshi ^a   Koyanagi, Jyunichi ^b   Komada, Fusao ^c   Saito, Setsuo ^a  

^a JOSAI UNIVERSITY   (Japan)

^b JOSAI INTERNATIONAL UNIVERSITY   (Japan)

^c HIMEJI DOKKYO UNIVERSITY   (Japan)

Author keywords

1,8 di O alkylaloe emodin; 15 aminochrysophanol; 15 selenocyanochrysophanol; 15 thiocyanochrysophanol; Cytotoxic effect

Indexed keywords

1,8 DI O HEXYLCHRYSOPHANOL DERIVATIVE; 15 AMINOCHRYSOPHANOL DERIVATIVE; 15 SELENOCYANOCHRYSOPHANOL DERIVATIVE; 15 THIOCYANOCHRYSOPHANOL DERIVATIVE; 2 PYRROLIDONE DERIVATIVE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALOE EMODIN; CHRYSOPHANIC ACID DERIVATIVE; DIETHYLAMINE; DIETHYLAMINO GROUP; DODECYL GROUP; GLYCOPROTEIN P; HEXYL GROUP; IMIDAZOLINE DERIVATIVE; IMIDAZOLYL GROUP; METHYL GROUP; METHYLPIPERAZINYL GROUP; OCTADECYL GROUP; PIPERIDINYL GROUP; PROPYL GROUP; PYRROLIDINYL GROUP; SELENOCYANO GROUP; THIOCYANO GROUP; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CELL LINE; CELL STRAIN HCT116; CELL STRAIN HEPG2; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SUBSTITUTION REACTION;

ALOE; ANTHRAQUINONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; ORGANOSELENIUM COMPOUNDS; P-GLYCOPROTEIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; TETRAZOLIUM SALTS; THIAZOLES;

EID: 42049111396     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.56.497     Document Type: Article

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