Synthetic mimetics of the gp130 binding site for viral interleukin-6 as inhibitors of the vIL-6-gp130 interaction

Chemical Biology and Drug Design

Volumn 71, Issue 5, 2008, Pages 494-500

  Sudarman, Enge ^a   Bollati Fogolín, Mariela ^a,b   Hafner, Martin ^a   Müller, Werner ^a,c   Scheller, Jürgen ^d   Rose John, Stefan ^d   Eichler, Jutta ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF KIEL   (Germany)

Author keywords

Binding site; gp130; Interleukin 6; Mimicry; Peptide; Protein ligand interactions

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6; JANUS KINASE 1; STAT1 PROTEIN; STAT3 PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL PROLIFERATION; ENZYME ACTIVATION; HUMAN HERPESVIRUS 8; MOLECULAR INTERACTION; MOLECULAR MIMICRY; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

BINDING SITES; CYTOKINE RECEPTOR GP130; HERPESVIRUS 8, HUMAN; HUMANS; INTERLEUKIN-6; MOLECULAR MIMICRY; PEPTIDES; PROTEIN BINDING; RECEPTORS, VIRUS; VIRAL PROTEINS;

HERPESVIRIDAE;

EID: 42049100583     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2008.00649.x     Document Type: Article

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