Synthetic mimetics of the CD4 binding site of HIV-1 gp120 for the design of immunogens

Angewandte Chemie - International Edition

Volumn 46, Issue 8, 2007, Pages 1253-1255

  Franke, Raimo ^a   Hirsch, Tatjana ^a   Overwin, Heike ^a   Eichler, Jutta ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Biomimetic synthesis; HIV 1 gp120; Peptides; Protein design; Synthetic vaccines

Indexed keywords

BINDING SITES; IMMUNOLOGY; MOLECULAR DYNAMICS; PROTEINS; VIRUSES;

BIOMIMETIC SYNTHESIS; HIV-1 GP120; PROTEIN DESIGN; SYNTHETIC VACCINES;

BIOMIMETICS;

BIOMIMETIC MATERIAL; CD4 ANTIGEN; GLYCOPROTEIN GP 120; MONOCLONAL ANTIBODY;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; IC 50; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; PROTEIN QUATERNARY STRUCTURE; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; BINDING SITES; BIOMIMETIC MATERIALS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HIV ENVELOPE PROTEIN GP120; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, QUATERNARY;

EID: 34247180030     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200603274     Document Type: Article

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