Visualisation of the kinetics of macrophage infiltration during experimental autoimmune encephalomyelitis by magnetic resonance imaging

Journal of Neuroimmunology

Volumn 195, Issue 1-2, 2008, Pages 1-6

  Baeten, Kurt ^a   Hendriks, Jerome JA ^a   Hellings, Niels ^a   Theunissen, Evi ^a   Vanderlocht, Joris ^a   Ryck, Leen De ^a   Gelan, Jan ^b   Stinissen, Piet ^a   Adriaensens, Peter ^b  

^a HASSELT UNIVERSITY   (Belgium)

^b HASSELT UNIVERSITY   (Belgium)

Author keywords

Experimental autoimmune encephalomyelitis; Magnetic resonance imaging; Multiple sclerosis; Ultra small particles of iron oxide

Indexed keywords

ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; MACROPHAGE MIGRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL MIGRATION ASSAYS, MACROPHAGE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FERRIC COMPOUNDS; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MYELIN BASIC PROTEINS; RATS; RATS, INBRED LEW; TIME FACTORS;

EID: 42049089740     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.11.008     Document Type: Article

References (17)

1. Berger, Hiestand P., Kindler-Baumann D., Rudin M., and Rausch M. Analysis of lesion development during acute inflammation and remission in a rat model of experimental autoimmune encephalomyelitis by visualization of macrophage infiltration, demyelination and blood-brain barrier damage. NMR biomed. 19 (2006) 101-107
2. Bulte, Arbab A.S., Douglas T., and Frank J.A. Preparation of magnetically labeled cells for cell tracking by magnetic resonance imaging. Methods Enzymol. 386 (2004) 275-299
3. Dousset, Ballarino L., Delalande C., Coussemacq M., Canioni P., Petry K.G., and Caille J.M. Comparison of ultrasmall particles of iron oxide (USPIO)-enhanced T2-weighted, conventional T2-weighted, and gadolinium-enhanced T1-weighted MR images in rats with experimental autoimmune encephalomyelitis. AJNR Am. J. Neuroradiol. 20 (1999) 223-227
4. Dousset, Brochet B., Deloire M.S., Lagoarde L., Barroso B., Caille J.M., and Petry K.G. MR imaging of relapsing multiple sclerosis patients using ultra-small-particle iron oxide and compared with gadolinium. AJNR Am. J. Neuroradiol. 27 (2006) 1000-1005
5. Ffrench-Constant. Pathogenesis of multiple sclerosis. Lancet 343 (1994) 271-275
6. Floris, Blezer E.L., Schreibelt G., Dopp E., van der Pol S.M., Schadee-Eestermans I.L., Nicolay K., Dijkstra C.D., and de Vries H.E. Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis: a quantitative MRI study. Brain 127 (2004) 616-627
7. Hellings, Raus J., and Stinissen P. Insights into the immunopathogenesis of multiple sclerosis. Immunol. Res. 25 (2002) 27-51
8. Hendriks, Teunissen C.E., de Vries H.E., and Dijkstra C.D. Macrophages and neurodegeneration. Brain Res. Brain Res. Rev. 48 (2005) 185-195
9. Imrich, and Harzer K. On the role of peripheral macrophages during active experimental allergic encephalomyelitis (EAE). J. Neural Transm. 108 (2001) 379-395
10. Kappos, Moeri D., Radue E.W., Schoetzau A., Schweikert K., Barkhof F., Miller D., Guttmann C.R.G., Weiner H.L., Gasperini C., and Filippi M. Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Lancet 353 (1999) 964-969
11. Lawson, Perry V.H., Dri P., and Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience. 39 (1999) 151-170
12. Lee, Smith S., Palace J., Narayanan S., Silver N., Minicucci L., Filippi M., Miller D.H., Arnold D.L., and Matthews P.M. Spatial mapping of T-2 and gadolinium-enhancing T-1 lesion volumes in multiple sclerosis: evidence for distinct mechanisms of lesion genesis?. Brain 122 (1999) 1261-1270
13. Napoli, and Bakshi R. Magnetic resonance imaging in multiple sclerosis. Rev. Neurol. Dis. 2 (2005) 109-116
14. Nguyen, McCombe P.A., and Pender M.P. Macrophage apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. J. Autoimmun. 7 (1994) 145-152
15. Rausch, Hiestand P., Baumann D., Cannet C., and Rudin M. MRI-based monitoring of inflammation and tissue damage in acute and chronic relapsing EAE. Magn. Reson. Med. 50 (2003) 309-314
16. Traboulsee, and Li D.K. The role of MRI in the diagnosis of multiple sclerosis. Adv. Neurol. 98 (2006) 125-146
17. Weissleder, Elizondo G., Wittenberg J., Rabito C.A., Bengele H.H., and Josephson L. Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging. Radiology 175 (1990) 489-493