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Volumn 7, Issue 5, 2008, Pages 375-376

Towards gene therapy for Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC LEVO AMINO ACID DECARBOXYLASE; DOPAMINE; FLUORINE 18; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUTAMATE DECARBOXYLASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; LEVODOPA; NEUROTROPHIC FACTOR; NEURTURIN; PARVOVIRUS VECTOR; TYROSINE 3 MONOOXYGENASE;

EID: 41949128614     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(08)70066-8     Document Type: Letter
Times cited : (20)

References (9)
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    • Olanow C., Obeso J., and Stocchi F. Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications. Lancet Neurology 5 (2006) 677-687
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    • Olanow, C.1    Obeso, J.2    Stocchi, F.3
  • 2
    • 0034721690 scopus 로고    scopus 로고
    • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
    • Kordower J., Emborg M., Bloch J., et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290 (2000) 767-773
    • (2000) Science , vol.290 , pp. 767-773
    • Kordower, J.1    Emborg, M.2    Bloch, J.3
  • 3
    • 41949110690 scopus 로고    scopus 로고
    • Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
    • Marks W., Ostrem J., Verhagen L., et al. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol 7 (2008) 400-408
    • (2008) Lancet Neurol , vol.7 , pp. 400-408
    • Marks, W.1    Ostrem, J.2    Verhagen, L.3
  • 4
    • 33748083041 scopus 로고    scopus 로고
    • Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC
    • Bankiewicz K., Forsayeth J., Eberling J., et al. Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC. Mol Ther 14 (2006) 571-577
    • (2006) Mol Ther , vol.14 , pp. 571-577
    • Bankiewicz, K.1    Forsayeth, J.2    Eberling, J.3
  • 5
    • 0037007106 scopus 로고    scopus 로고
    • Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer
    • Kirik D., Georgievska B., Burgeret C., et al. Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer. Proc Natl Acad Sci U S A 99 (2002) 4708-4713
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4708-4713
    • Kirik, D.1    Georgievska, B.2    Burgeret, C.3
  • 6
    • 34250683023 scopus 로고    scopus 로고
    • Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial
    • Kaplitt M., Feigin A., Tang C., et al. Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet 369 (2007) 2097-2105
    • (2007) Lancet , vol.369 , pp. 2097-2105
    • Kaplitt, M.1    Feigin, A.2    Tang, C.3
  • 7
    • 0036897235 scopus 로고    scopus 로고
    • Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease
    • Azzouz M., Martin-Rendon E., Barber R., et al. Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease. J Neurosci 22 (2002) 10302-10312
    • (2002) J Neurosci , vol.22 , pp. 10302-10312
    • Azzouz, M.1    Martin-Rendon, E.2    Barber, R.3
  • 9
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    • Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys
    • Kordower J., Herzog C., Dass B., et al. Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Ann Neurol 60 (2006) 706-715
    • (2006) Ann Neurol , vol.60 , pp. 706-715
    • Kordower, J.1    Herzog, C.2    Dass, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.