Localization of the sulphonylurea receptor subunits, SUR2A and SUR2B, in rat renal tubular epithelium

Tohoku Journal of Experimental Medicine

Volumn 214, Issue 3, 2008, Pages 247-256

  Zhou, Ming ^a   He, Hui Jing ^a   Tanaka, Osamu ^b   Suzuki, Ryoji ^a   Sekiguchi, Masaki ^b   Yasuoka, Yukiko ^c   Kawahara, Katsumasa ^c   Itoh, Hideaki ^d   Abe, Hiroshi ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d AKITA UNIVERSITY   (Japan)

Author keywords

ATP sensitive K+ channel; Immunoelectron microscopy; Immunohistochemistry; Kidney; Sulphonylurea receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; SULFONYLUREA RECEPTOR; SULFONYLUREA RECEPTOR 2A; SULFONYLUREA RECEPTOR 2B; UNCLASSIFIED DRUG; ABC TRANSPORTER; DRUG RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; MESSENGER RNA; POTASSIUM CHANNEL; PROTEIN SUBUNIT;

ANIMAL TISSUE; ARTICLE; ENDOPLASMIC RETICULUM; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; KIDNEY FUNCTION; KIDNEY TUBULE EPITHELIUM; MALE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; EPITHELIUM; GENE EXPRESSION REGULATION; GENETICS; KIDNEY TUBULE; METABOLISM; ULTRASTRUCTURE; WESTERN BLOTTING; WISTAR RAT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; EPITHELIUM; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULES; MALE; MICROSCOPY, IMMUNOELECTRON; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN SUBUNITS; RATS; RATS, WISTAR; RECEPTORS, DRUG; RNA, MESSENGER;

EID: 41949128536     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.214.247     Document Type: Article

References (33)

1. Aguilar-Bryan, L., Clement, J.R, 4th., Gonzalez, G., Kunjilwar, K., Babenko, A. & Bryan, J. (1998) Toward understanding the assembly and structure of KATP channels. Physiol. Rev., 78, 227-245.
2. Bajgar, R., Seetharaman, S., Kowaltowski, A.J., Garlid, K.D. & Paucek, P. (2001) Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. J. Biol. Chem., 276, 33369-33374.
3. Beesley, A.H., Qureshi, I.Z., Giesberts, A.N., Parker, A.J. & White, S.J. (1999) Expression of sulphonylurea receptor protein in mouse kidney. Pflugers. Arch., 438, 1-7.
4. + channel. II. Cloning and distribution of alternative forms. Am. J. Physiol., 268, F1132-F1140.
5. Brochiero, E., Wallendorf, B., Gagnon, D., Laprade, R. & Lapointe, J.Y. (2002) Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel. Am. J. Physiol. Renal. Physiol., 282, F289-F300.
6. Chutkow,,W.A., Simon, M.C., Le Beau, M.M. & Burant, C.F. (1996), Cloning, tissue expression, and chromosomal localization of SUR2, the putative drug-binding subunit of cardiac, skeletal muscle, and vascular KATP channels. Diabetes, 45, 1439-1445.
7. Chutkow, W.A., Pu, J., Wheeler, M.T., Wada, T., Makielski, J.C., Burant, C.F. & McNally, E.M. (2002) Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels. J. Clin. Invest., 110, 203-208.
8. Clement, J.P., 4th., Kunjilwar, K., Gonzalez, G., Schwanstecher, M., Panten, U., Aguilar-Bryan, L. & Bryan, J. (1997) Association and stoichiometry of K(ATP) channel subunits. Neuron, 18, 827-838.
9. Hernandez-Sanchez, C., Wood, T.L. & LeRoith, D. (1997) Developmental and tissue-specific sulfonylurea receptor gene expression. Endocrinology, 138, 705-711.
10. Inagaki, N., Gonoi, T., Clement, J.P., 4th., Namba, N., Inazawa, J., Gonzalez, G., Aguilar-Bryan, L., Seino, S. & Bryan, J. (1995a) Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science, 270, 1166-1170.
11. Inagaki, N., Tsuura, Y., Namba, N., Masuda, K., Gonoi, T., Horie, M., Seino, Y., Mizuta, M. & Seino, S. (1995b) Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J. Biol. Chem., 270, 5691-5694.
12. Inagaki, N., Gonoi, T., Clement, J.P., 4th., Wang, C.Z., Aguilar-Bryan, L., Bryan, J. & Seino, S. (1996) A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels. Neuron, 16, 1011-1017.
13. Isomoto, S., Kondo, C., Yamada, M., Matsumoto, S., Higashiguchi, O., Horio, Y., Matsuzawa, Y. & Kurachi, Y. (1996) A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel. J. Biol. Chem., 271, 24321-24324.
14. Ito, M., Inanobe, A., Horio, Y., Hibino, H., Isomoto, S., Ito, H., Mori, K., Tonosaki, A., Tomoike, H. & Kurachi, Y. (1996) Immunolocalization of an inwardly rectifying K+ channel, K(AB)-2 (Kir4.1), in the basolateral membrane of renal distal tubular epithelia. FEBS Lett., 388, 11-15.
15. Itoh, H., Komatsuda, A., Ohtani, H., Wakui, H., Imai, H. Sawada, K., Otaka, M., Ogura, M., Suzuki, A. & Hamada, F. (2002) Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration. Eur. J. Biochem., 269, 5931-5938.
16. Kawahara, K. & Anzai, N. (1997) Potassium transport and potassium channels in the kidney tubules. Jpn. J. Physiol., 47, 1-10.
17. Kawahara, K., Hunter, M. & Giebisch, G. (1987) Potassium channels in Necturus proximal tubule. Am. J. Physiol., 253, F488-F494.
18. Kubo, Y, Baldwin, T.J., Jan, Y.N. & Jan, L.Y. (1993) Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature, 362, 127-133.
19. Lacza, Z., Snipes, J.A., Miller, A.W., Szabo, C., Grover, G. & Busija, D.W. (2003) Heart mitochondria contain functional ATP-dependent K+ channels. J. Mol. Cell Cardiol., 35, 1339-1347.
20. Lee, W.S. & Hebert, S.C. (1995) ROMK inwardly rectifying ATP-sensitive K+ channel. I. Expression in rat distal nephron segments. Am. J. Physiol., 168, F1124-F1131.
21. Noma, A. (1983) ATP-regulated K+ channels in cardiac muscle. Nature, 305, 147-148.
22. Noulin, J.F., Brochiero, E., Coady, M.J., Laprade, R. & Lapointe, J.Y, (2001) Molecular identity and regulation of renal potassium channels. Jpn. J. Physiol., 51, 631-647.
23. Noulin, L.F., Brochiero, E., Lapointe, J.Y. & Laprade, R. (1999) Two types of K(+) channels at the basolateral membrane of proximal tubule: inhibitory effect of taurine. Am. J. Physiol., 277, F290-F297.
24. Sakura, H., Ammala, C., Smith, P.A., Gribble, F.M. & Ashcroft, F.M. (1995) Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle. FEBS. Lett., 377, 338-344.
25. Seino, S. & Miki, T. (2003) Physiological and pathophysiological roles of ATP-sensitive K+ channels. Prog. Biophys. Mol. Biol., 81, 133-176.
26. Seino, S. & Miki, T. (2004) Gene targeting approach to clarification of ion channel function: studies of Kir6.x null mice. J. Physiol., 554, 295-300.
27. Szamosfalvi, B., Cortes, P., Alviani, R., Asano, K., Riser, B.L., Zasuwa, G. & Yee, J. (2002) Putative subunits of the rat mesangial KATP a type 2B sulfonylurea receptor and an inwardly rectifying K+ channel. Kidney Int., 61, 1739-1749.
28. Szewczyk, A., Wojcik, G., Lobanov, N.A. & Nalecz, M.J. (1997) The mitochondrial sulfonylurea receptor: identification and characterization. Biochem. Biophys. Res. Commun., 230, 611-615.
29. Wang, X., Wu, J., Li, L., Chen, F., Wang, R. & Jiang, C. (2003) Hypercapnic acidosis activates KATP channels in vascular smooth muscles. Circ. Res., 92, 1225-1232.
30. Yamada, M., Isomoto, S., Matsumoto, S., Kondo, C., Shindo, T., Horio, Y. & Kurachi, Y. (1997) Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel. J. Physiol., 499 (Pt 3), 715-720.
31. Zhou, M., Tanaka, O., Sekiguchi, M., He, H.J., Yasuoka, Y., Itoh, H., Kawahara, K. & Abe, H. (2005) ATP-sensitive K+-channel subunits on the mitochondria and endoplasmic reticulum of rat cardiomyocytes. J. Histochem. Cytochem., 53, 1491-1500.
32. Zhou, M., He, H.J., Suzuki, R., Liu, K.X., Tanaka, O., Sekiguchi, M., Itoh, H., Kawahara, K. & Abe, H. (2007a) Localization of sulfonylurea receptor subunits, SUR2A and SUR2B, in rat heart. J. Histochem. Cytochem., 55, 795-804.
33. Zhou, M., He, H.J., Suzuki, R., Tanaka, O., Sekiguchi, M., Yasuoka, Y., Kawahara, K., Itoh, H. & Abe, H. (2007b) Expression of ATP sensitive K+ channel subunit Kir6.1 in rat kidney. Eur. J. Histochem., 51, 43-51.