Role of extracellular superoxide in neutrophil activation: Interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production

American Journal of Physiology - Cell Physiology

Volumn 294, Issue 4, 2008, Pages

  Lorne, Emmanuel ^a,d   Zmijewski, Jaroslaw W ^a,b   Zhao, Xia ^a   Liu, Gang ^a   Tsuruta, Yuko ^a   Park, Young Jun ^a   Dupont, Hervé ^c   Abraham, Edward ^a  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c AMIENS UNIVERSITY HOSPITAL   (France)

^d INSERM   (France)

Author keywords

Glycosaminoglycans; Heparin; Nuclear factor b; Reactive oxygen species; Signal transduction; Toll like receptor 4

Indexed keywords

GLYCOSAMINOGLYCAN; HEPARIN; HYPOXANTHINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUMAZINE; MACROPHAGE INFLAMMATORY PROTEIN 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GEL MOBILITY SHIFT ASSAY; IMMUNOPRECIPITATION; INFLAMMATION; LEUKOCYTE ACTIVATION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; WESTERN BLOTTING;

ANIMALS; CYTOKINES; EXTRACELLULAR FLUID; HEPARIN; HYPOXANTHINE; MALE; MICE; MICE, KNOCKOUT; NEUTROPHIL ACTIVATION; NEUTROPHILS; NF-KAPPA B; SUPEROXIDES; TOLL-LIKE RECEPTOR 4; XANTHINE OXIDASE;

EID: 41949118525     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00454.2007     Document Type: Article

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