An automated method for the simultaneous determination of pravastatin, 3-hydroxy isomeric metabolite, pravalactone and fenofibric acid in human plasma by sensitive liquid chromatography combined with diode array and tandem mass spectrometry detection

Journal of Chromatography A

Volumn 1189, Issue 1-2, 2008, Pages 493-502

  Mertens, B ^a   Cahay, B ^a   Klinkenberg, R ^a   Streel, B ^a  

^a Galephar MF   (Belgium)

Author keywords

3 Hydroxy isomeric metabolite; Fenofibric acid; LC DAD MS MS; Pharmacokinetics; Pravalactone; Pravastatin; Solid phase extraction; Validation

Indexed keywords

FENOFIBRIC ACID; HYDROXY ISOMERIC METABOLITES; PRAVALACTONE; PRAVASTATIN; SOLID-PHASE EXTRACTION (SPE);

ATMOSPHERIC PRESSURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PHARMACOKINETICS; PHASE SEPARATION;

PLASMA (HUMAN);

3 HYDROXY ISOMERIC METABOLITE; ACETONITRILE; AMMONIUM ACETATE; DRUG METABOLITE; FENOFIBRIC ACID; LACTONE DERIVATIVE; METHANOL; PRAVALACTONE; PRAVASTATIN; SILICON DIOXIDE; SULINDAC; TRIAMCINOLONE; UNCLASSIFIED DRUG;

ARTICLE; ATMOSPHERIC PRESSURE; DIODE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG SELECTIVITY; DRUG STABILITY; IONIZATION; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; STANDARD; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; HUMANS; MOLECULAR STRUCTURE; PRAVASTATIN; PROCETOFEN; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 41949083173     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.01.060     Document Type: Article

References (45)

1. O'Connor P., Feely J., and Shepherd J. Br. Med. J. 300 (1990) 667
2. Caldwell J., Strolin-Benedetti M., and Weil A. Arzneim. -Forsch. 26 (1976) 896
3. Rössner S., and Orö L. Atherosclerosis 38 (1981) 273
4. Shepherd J. Postgrad. Med. J. 69 (1993) S34
5. Mainguy Y., Vidal R., and Strolin-Benedetti M. J. Pharm. Clin. 4 (1985) 59
6. C. Dollery, Therapeutic Drugs, Suppl. 2, Churchill Livingstone, Edinburgh, 1991, p. S289.
7. Williams F.M. Clin. Pharmacokin. 10 (1985) 392
8. Benedetti S., Guichard M., Vidal J.P., and Donath R. Acta Pharmacol. Toxicol. 59 (1986) 167
9. Guichard J.P., and Sauron L.-P. Curr. Ther. Res. 54 (1993) 610
10. Masnatta L.C., Cuniberti L.A., Rey R.H., and Werba J.P. J. Chromatogr. B 687 (1996) 437
11. Kornitzer M., Dramaix M., Vandenbroek M.D., Everaert L., and Gerlinger C. Atherosclerosis 110 (1994) S49
12. Pravastatin Prescribing Information, Squibb and Sons, New Jersey, USA, 1995.
13. Önal A., and Sagirli O. Chromatographia 64 (2006) 157
14. European Pharmacopoeia, 6th Ed., Monograph 01/2008, 1322.
15. European Pharmacopoeia, 6th Ed., Monograph 01/2008, 2059.
16. United States Pharmacopoeia, 30th Ed., National Formulary 25, 2007, p. 2117.
17. United States Pharmacopoeia, 30th Ed., National Formulary 25, Suppl. 2, 2007, p. 4121.
18. United States Pharmacopoeia, 30th Ed., National Formulary 25, Suppl. 2, 2007, p. 4123.
19. François-Dainville E., and Astier A. J. Pharm. Clin. 1 (1982) 215
20. Weil A., Caldwell J., and Strolin-Benedetti M. Drug. Metab. Dispos. 16 (1988) 302
21. Abe S., Ono K., Mogi M., and Hayashi T. Yakugaku Zasshi 118 (1998) 447
22. Paillet M., Doucet D., Merdjan H., Chambrin P.Y., and Fredj G. J. Chromatogr. 375 (1986) 179
23. Cotta Ramusino A., and Carozzi A. J. Chromatogr. 383 (1986) 419
24. Desager J.P. J. Chromatogr. 145 (1978) 160
25. Elssom L.F., Hawkins D.R., and Chasseaud L.F. J. Chromatogr. 123 (1976) 463
26. Masnatta L.D., Cuniberti L.A., Rey R.H., and Werba J.P. J. Chromatogr. B 687 (1996) 437
27. El-Gindy A., Emara S., Mesbah M.K., and Hadad G.M. Farmaco 60 (2005) 425
28. Streel B., Hubert P., and Ceccato A. J. Chromatogr. B 742 (2000) 391
29. Yang A., Rogers J., and Zhao J. Proceedings of the 50th ASMS Conference on Mass Spectrometry and Allied Topics. Orlando, FL, June 2-6 (2002)
30. Kawabata K., Matsushima N., and Sasahara K. Biomed. Chromatogr. 12 (1998) 271
31. Whigan D.B., Ivashkiv E., and Cohen A.I. J. Pharm. Biomed. Anal. 7 (1989) 907
32. Funke P.T., Ivashkiv E., Arnold M.E., and Cohen A.I. Biomed. Environ. Mass Spectrom. 18 (1989) 904
33. Morris M.J., Gilbert J.D., Hsieh J.Y.-K., Matuszewski B.K., Ramjit H.G., and Bayne W.F. Biol. Mass Spectrom. 22 (1993) 1
34. Iacona I., Regazzi M.B., Buggia I., Villani P., Fiorito V., Molinaro M., and Guarnone E. Ther. Drug Monit. 16 (1994) 191
35. Siekmeier R., Gross W., and März W. Int. J. Clin. Pharmacol. Ther. 38 (2000) 419
36. Mulvana D., Jemal M., and Coates Pulver S. J. Pharm. Biomed. Anal. 23 (2000) 851
37. Otter K., and Mignat C. J. Chromatogr. B 708 (1998) 235
38. Dumousseaux C., Muramatsu S., Takasaki W., and Takahagi H. J. Pharm. Sci. 83 (1994) 1630
39. Guidance for industry: Bioanalytical Method Validation, U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Rockville, MD, May 2001.
40. Shah V.P., Midha K.K., Dighe S., McGilveray I.J., Skelly J.P., Yacobi A., Layloff T., Viswanathan C.T., Cook C.E., McDowall R.D., Pittman K.A., and Spector S. Pharm. Res. 9 (1992) 588
41. Hubert P., Nguyen-Huu J.-J., Boulanger B., Chapuzet E., Chiap P., Cohen N., Compagnon P.-A., Dewe W., Feinberg M., Lallier M., Laurentie M., Mercier N., Muzard G., Nivet C., and Valat L. STP Pharm. Prat. 13 (2003) 101
42. Chapuzet E., Mercier N., Bervoas-Martin S., Boulanger B., Chevalier P., Chiap P., Grandjean D., Hubert Ph., Lagorce P., Lallier M., Laparra M.C., Laurentie M., and Nivet J.C. STP Pharm. Prat. 7 (1997) 169
43. Hubert Ph., Chiap P., Crommen J., Boulanger B., Chapuzet E., Mercier N., Bervoas-Martin S., Chevalier P., Grandjean D., Lagorce P., Lallier M., Laparra M.C., Laurentie M., and Nivet J.C. Anal. Chim. Acta 391 (1999) 135
44. Buick A.R., Doig M.V., Jeal S.C., Land G.S., and Mac-Dowall R.D. J. Pharm. Biomed. Anal. 8 (1990) 629
45. ISO 5725-1, Application of the statistics - accuracy (trueness and precision) of the results and methods of measurement - Part 1: general principles and definitions, International Organization for Standardization (ISO), Geneva, 1994.