-
1
-
-
0030983708
-
Mortality by cause for eight regions of the world: Global Burden of Disease Study
-
Murray CJ, Lopez AD. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet 1997 349 : 1269 76.
-
(1997)
Lancet
, vol.349
, pp. 1269-76
-
-
Murray, C.J.1
Lopez, A.D.2
-
2
-
-
4344675455
-
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
-
Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004 364 : 709 21.
-
(2004)
Lancet
, vol.364
, pp. 709-21
-
-
Hogg, J.C.1
-
3
-
-
0032724630
-
Novel approaches and targets for treatment of chronic obstructive pulmonary disease
-
Barnes PJ. Novel approaches and targets for treatment of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999 160 : S72 9.
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.160
-
-
Barnes, P.J.1
-
4
-
-
0003736031
-
-
National Heart, Lung, and Blood Institute. Bethesda, MD: National Institutes of Health. [Accessed 23 April 2007.] Available from GOLD website:
-
National Heart, Lung, and Blood Institute. Global Initiative for Chronic Obstructive Lung Disease: Global Strategy for Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease (2006 update). Bethesda, MD : National Institutes of Health. [Accessed 23 April 2007.] Available from GOLD website: http://www.goldcopd.com
-
Global Initiative for Chronic Obstructive Lung Disease: Global Strategy for Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease (2006 Update).
-
-
-
5
-
-
0021175444
-
Role of the parasympathetic system in airway obstruction due to emphysema
-
Gross NJ, Skorodin MS. Role of the parasympathetic system in airway obstruction due to emphysema. N. Engl. J. Med. 1984 311 : 421 5.
-
(1984)
N. Engl. J. Med.
, vol.311
, pp. 421-5
-
-
Gross, N.J.1
Skorodin, M.S.2
-
6
-
-
0031774720
-
International union of pharmacology. XVII. Classification of muscarinic acetylcholine receptors
-
Caulfield MP, Birdsall NJ. International union of pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol. Rev. 1998 50 : 279 90.
-
(1998)
Pharmacol. Rev.
, vol.50
, pp. 279-90
-
-
Caulfield, M.P.1
Birdsall, N.J.2
-
7
-
-
0027509977
-
Muscarinic receptor subtypes in airways
-
Barnes PJ. Muscarinic receptor subtypes in airways. Life Sci. 1993 52 : 521 7.
-
(1993)
Life Sci.
, vol.52
, pp. 521-7
-
-
Barnes, P.J.1
-
8
-
-
27644530096
-
Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease
-
Belmonte KE. Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2005 2 : 297 304.
-
(2005)
Proc. Am. Thorac. Soc.
, vol.2
, pp. 297-304
-
-
Belmonte, K.E.1
-
9
-
-
27144522107
-
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M3 muscarinic acetylcholine receptor
-
Han SJ, Hamdan FF, Kim SK, Jacobson KA, Bloodworth LM et al. Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M3 muscarinic acetylcholine receptor. J. Biol. Chem. 2005 280 : 34849 58.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 34849-58
-
-
Han, S.J.1
Hamdan, F.F.2
Kim, S.K.3
Jacobson, K.A.4
Bloodworth, L.M.5
-
10
-
-
0030609973
-
Muscarinic M3 receptor coupling and regulation
-
Nahorski SR, Tobin AB, Willars GB. Muscarinic M3 receptor coupling and regulation. Life Sci. 1997 60 : 1039 45.
-
(1997)
Life Sci.
, vol.60
, pp. 1039-45
-
-
Nahorski, S.R.1
Tobin, A.B.2
Willars, G.B.3
-
11
-
-
27644482811
-
Beta2-agonist and anticholinergic drugs in the treatment of lung disease
-
Proskocil BJ, Fryer AD. Beta2-agonist and anticholinergic drugs in the treatment of lung disease. Proc. Am. Thorac. Soc. 2005 2 : 305 10.
-
(2005)
Proc. Am. Thorac. Soc.
, vol.2
, pp. 305-10
-
-
Proskocil, B.J.1
Fryer, A.D.2
-
12
-
-
0030898519
-
Muscarinic control of airway function
-
Zaagsma J, Roffel AF, Meurs H. Muscarinic control of airway function. Life Sci. 1997 60 : 1061 8.
-
(1997)
Life Sci.
, vol.60
, pp. 1061-8
-
-
Zaagsma, J.1
Roffel, A.F.2
Meurs, H.3
-
13
-
-
0029947711
-
Regulation by cAMP-dependent protein kinase of a G-protein-mediated phospholipase C
-
Liu M, Simon MI. Regulation by cAMP-dependent protein kinase of a G-protein-mediated phospholipase C. Nature 1996 382 : 83 7.
-
(1996)
Nature
, vol.382
, pp. 83-7
-
-
Liu, M.1
Simon, M.I.2
-
14
-
-
0032862341
-
Cross talk between m3-muscarinic and beta 2-adrenergic receptors at the level of receptor phosphorylation and desensitization
-
Budd DC, Challiss RA, Young KW, Tobin AB. Cross talk between m3-muscarinic and beta 2-adrenergic receptors at the level of receptor phosphorylation and desensitization. Mol. Pharmacol. 1999 56 : 813 23.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 813-23
-
-
Budd, D.C.1
Challiss, R.A.2
Young, K.W.3
Tobin, A.B.4
-
15
-
-
6944232728
-
National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Use of regularly scheduled albuterol treatment in asthma: Genotype-stratified, randomised, placebo-controlled cross-over trial
-
Israel E, Chinchilli VM, Ford JG, Boushey HA, Cherniack R et al. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet 2004 364 : 1505 12.
-
(2004)
Lancet
, vol.364
, pp. 1505-12
-
-
Israel, E.1
Chinchilli, V.M.2
Ford, J.G.3
Boushey, H.A.4
Cherniack, R.5
-
16
-
-
0026871146
-
A self-complete measure of health status for chronic airflow limitation. the St. George's Respiratory Questionnaire
-
Jones PW, Quirk FH, Baveystock CM, Littlejohns P. A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire. Am. Rev. Respir. Dis. 1992 145 : 1321 7.
-
(1992)
Am. Rev. Respir. Dis.
, vol.145
, pp. 1321-7
-
-
Jones, P.W.1
Quirk, F.H.2
Baveystock, C.M.3
Littlejohns, P.4
-
17
-
-
0031466866
-
Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing
-
Martinez FD, Graves PE, Baldini M, Solomon S, Erickson R. Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing. J. Clin. Invest. 1997 100 : 3184 8.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 3184-8
-
-
Martinez, F.D.1
Graves, P.E.2
Baldini, M.3
Solomon, S.4
Erickson, R.5
-
18
-
-
0442288082
-
Beta2-adrenergic receptor haplotypes in mild, moderate and fatal/near fatal asthma
-
Weir TD, Mallek N, Sandford AJ, Bai TR, Awadh N et al. Beta2-adrenergic receptor haplotypes in mild, moderate and fatal/near fatal asthma. Am. J. Respir. Crit. Care Med. 1998 158 : 787 91.
-
(1998)
Am. J. Respir. Crit. Care Med.
, vol.158
, pp. 787-91
-
-
Weir, T.D.1
Mallek, N.2
Sandford, A.J.3
Bai, T.R.4
Awadh, N.5
-
19
-
-
0342545990
-
Association of beta 2-adrenoreceptor variants with bronchial hyperresponsiveness
-
Ulbrecht M, Hergeth MT, Wjst M, Heinrich J, Bickeboller H et al. Association of beta 2-adrenoreceptor variants with bronchial hyperresponsiveness. Am. J. Respir. Crit. Care Med. 2000 161 : 469 74.
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.161
, pp. 469-74
-
-
Ulbrecht, M.1
Hergeth, M.T.2
Wjst, M.3
Heinrich, J.4
Bickeboller, H.5
-
20
-
-
33645110637
-
National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Beta-adrenergic receptor polymorphisms and response to salmeterol
-
Jr
-
Wechsler ME, Lehman E, Lazarus SC, Lemanske RF Jr, Boushey HA et al. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Beta-adrenergic receptor polymorphisms and response to salmeterol. Am. J. Respir. Crit. Care Med. 2006 173 : 519 26.
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.173
, pp. 519-26
-
-
Wechsler, M.E.1
Lehman, E.2
Lazarus, S.C.3
Lemanske, R.F.4
Boushey, H.A.5
-
21
-
-
85047694597
-
Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox
-
McGraw DW, Almoosa KF, Paul RJ, Kobilka BK, Liggett SB. Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox. J. Clin. Invest. 2003 112 : 619 26.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 619-26
-
-
McGraw, D.W.1
Almoosa, K.F.2
Paul, R.J.3
Kobilka, B.K.4
Liggett, S.B.5
-
22
-
-
33749439171
-
Genetics of chronic obstructive pulmonary disease, beyond alpha1-antitrypsin deficiency
-
Sampsonas F, Karkoulias K, Kaparianos A, Spiropoulos K. Genetics of chronic obstructive pulmonary disease, beyond alpha1-antitrypsin deficiency. Curr. Med. Chem. 2006 13 : 2857 73.
-
(2006)
Curr. Med. Chem.
, vol.13
, pp. 2857-73
-
-
Sampsonas, F.1
Karkoulias, K.2
Kaparianos, A.3
Spiropoulos, K.4
-
23
-
-
17044453955
-
Increased expression of transforming growth factor-beta 1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD)
-
Takizawa H, Tanaka M, Takami K, Ohtoshi T, Ito K et al. Increased expression of transforming growth factor-beta 1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD). Am. J. Respir. Crit. Care Med. 2001 163 : 1476 83.
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.163
, pp. 1476-83
-
-
Takizawa, H.1
Tanaka, M.2
Takami, K.3
Ohtoshi, T.4
Ito, K.5
-
24
-
-
20244379268
-
Polymorphisms of TNF-alpha, IL1-beta, and IL1RN genes in chronic obstructive pulmonary disease
-
Hegab AE, Sakamoto T, Saitoh W, Nomura A, Ishii Y et al. Polymorphisms of TNF-alpha, IL1-beta, and IL1RN genes in chronic obstructive pulmonary disease. Biochem. Biophys. Res. Commun. 2005 329 : 1246 52.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.329
, pp. 1246-52
-
-
Hegab, A.E.1
Sakamoto, T.2
Saitoh, W.3
Nomura, A.4
Ishii, Y.5
-
25
-
-
10444267325
-
Polymorphisms of IL4, IL13, and ADRB2 genes in COPD
-
Hegab AE, Sakamoto T, Saitoh W, Massoud HH, Massoud HM et al. Polymorphisms of IL4, IL13, and ADRB2 genes in COPD. Chest 2004 126 : 1832 9.
-
(2004)
Chest
, vol.126
, pp. 1832-9
-
-
Hegab, A.E.1
Sakamoto, T.2
Saitoh, W.3
Massoud, H.H.4
Massoud, H.M.5
-
26
-
-
33751270109
-
Beta2-adrenergic receptor polymorphisms are associated with asthma and COPD in adults
-
Matheson MC, Ellis JA, Raven J, Johns DP, Walters EH et al. Beta2-adrenergic receptor polymorphisms are associated with asthma and COPD in adults. J. Hum. Genet. 2006 51 : 943 51.
-
(2006)
J. Hum. Genet.
, vol.51
, pp. 943-51
-
-
Matheson, M.C.1
Ellis, J.A.2
Raven, J.3
Johns, D.P.4
Walters, E.H.5
-
27
-
-
0035170742
-
Polymorphism of the beta 2-adrenoceptor in COPD in Chinese subjects
-
Ho LI, Harn HJ, Chen CJ, Tsai NM. Polymorphism of the beta 2-adrenoceptor in COPD in Chinese subjects. Chest 2001 120 : 1493 9.
-
(2001)
Chest
, vol.120
, pp. 1493-9
-
-
Ho, L.I.1
Harn, H.J.2
Chen, C.J.3
Tsai, N.M.4
-
28
-
-
0035135566
-
Susceptibility genes for rapid decline of lung function in the lung health study
-
Sandford AJ, Chagani T, Weir TD, Connett JE, Anthonisen NR et al. Susceptibility genes for rapid decline of lung function in the lung health study. Am. J. Respir. Crit. Care Med. 2001 163 : 469 73.
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.163
, pp. 469-73
-
-
Sandford, A.J.1
Chagani, T.2
Weir, T.D.3
Connett, J.E.4
Anthonisen, N.R.5
-
29
-
-
22644432807
-
A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population
-
Van Diemen CC, Postma DS, Vonk JM, Bruinenberg M, Schouten JP et al. A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population. Am. J. Respir. Crit. Care Med. 2005 172 : 329 33.
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.172
, pp. 329-33
-
-
Van Diemen, C.C.1
Postma, D.S.2
Vonk, J.M.3
Bruinenberg, M.4
Schouten, J.P.5
-
30
-
-
0036683266
-
Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers
-
He JQ, Ruan J, Connett JE, Anthonisen NR, Pare PD et al. Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers. Am. J. Respir. Crit. Care Med. 2002 166 : 323 8.
-
(2002)
Am. J. Respir. Crit. Care Med.
, vol.166
, pp. 323-8
-
-
He, J.Q.1
Ruan, J.2
Connett, J.E.3
Anthonisen, N.R.4
Pare, P.D.5
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