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Volumn 29, Issue 4, 2008, Pages 762-765

Constitutional CHEK2 mutations are associated with a decreased risk of lung and laryngeal cancers

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 2; PROTEIN P53; TOBACCO SMOKE;

EID: 41849112710     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn044     Document Type: Article
Times cited : (42)

References (24)
  • 1
    • 22044445244 scopus 로고    scopus 로고
    • Association of two mutations in the CHEK2 gene with breast cancer
    • Bogdanova,N. et al. (2005) Association of two mutations in the CHEK2 gene with breast cancer. Int. J. Cancer, 116, 263-266.
    • (2005) Int. J. Cancer , vol.116 , pp. 263-266
    • Bogdanova, N.1
  • 2
    • 0033566082 scopus 로고    scopus 로고
    • Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
    • Chaturvedi,P. et al. (1999) Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 18, 4047-4054.
    • (1999) Oncogene , vol.18 , pp. 4047-4054
    • Chaturvedi, P.1
  • 3
    • 18544389716 scopus 로고    scopus 로고
    • Low-penetrance susceptibility to breast cancer due to CHEK2*1100de1C in noncarriers of BRCA1 or BRCA2 mutations
    • CHEK2 Breast Cancer Consortium
    • CHEK2 Breast Cancer Consortium (2002) Low-penetrance susceptibility to breast cancer due to CHEK2*1100de1C in noncarriers of BRCA1 or BRCA2 mutations. Nat. Genet., 31, 55-59.
    • (2002) Nat. Genet , vol.31 , pp. 55-59
  • 4
    • 3042582651 scopus 로고    scopus 로고
    • CHEK2* 1100de1C and susceptibility to breast cancer: A collaborative analysis involving 10,860 breast cancer cases and 9,065 controls ftom 10 studies
    • CHEK2 Breast Cancer Case-Control consortium
    • CHEK2 Breast Cancer Case-Control consortium (2004) CHEK2* 1100de1C and susceptibility to breast cancer: A collaborative analysis involving 10,860 breast cancer cases and 9,065 controls ftom 10 studies. Am. J. Hum. Genet., 74, 1175-1182.
    • (2004) Am. J. Hum. Genet , vol.74 , pp. 1175-1182
  • 5
    • 8844220451 scopus 로고    scopus 로고
    • CHEK2 is a multiorgan cancer susceptibility gene
    • Cybulski,C. et al. (2004) CHEK2 is a multiorgan cancer susceptibility gene. Am. J. Hum. Genet., 75, 1131-1135.
    • (2004) Am. J. Hum. Genet , vol.75 , pp. 1131-1135
    • Cybulski, C.1
  • 6
    • 0037320555 scopus 로고    scopus 로고
    • Mutations in CHEK2 associated with prostate cancer risk
    • Dong,X. et al. (2003) Mutations in CHEK2 associated with prostate cancer risk. Am. J. Hum. Genet., 72, 270-280.
    • (2003) Am. J. Hum. Genet , vol.72 , pp. 270-280
    • Dong, X.1
  • 7
    • 3843071233 scopus 로고    scopus 로고
    • CHEK2 variant I157T may be associated with increased breast cancer risk
    • Kilpivaara,O. et al. (2004) CHEK2 variant I157T may be associated with increased breast cancer risk. Int. J. Cancer, 111, 543-547.
    • (2004) Int. J. Cancer , vol.111 , pp. 543-547
    • Kilpivaara, O.1
  • 8
    • 0034641724 scopus 로고    scopus 로고
    • Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
    • Matsuoka,S. et al. (2000) Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc. Natl Acad. Sci. USA, 97, 10389-10394.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 10389-10394
    • Matsuoka, S.1
  • 9
    • 0347626108 scopus 로고    scopus 로고
    • The CHEK2*1100de1C variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families
    • Oldenburg,R.A. et al. (2003) The CHEK2*1100de1C variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families. Cancer Res., 63, 8153-8157.
    • (2003) Cancer Res , vol.63 , pp. 8153-8157
    • Oldenburg, R.A.1
  • 10
    • 33745952966 scopus 로고    scopus 로고
    • Variants in the ATM-BRCA2-CHEK2 axis predispose to chronic lymphocytic leukaemia
    • Rudd,M.F. et al. (2006) Variants in the ATM-BRCA2-CHEK2 axis predispose to chronic lymphocytic leukaemia. Blood, 108, 638-644.
    • (2006) Blood , vol.108 , pp. 638-644
    • Rudd, M.F.1
  • 11
    • 0347382813 scopus 로고    scopus 로고
    • CHEK2 variants associate with hereditary prostate cancer
    • Seppala,E.H. et al. (2003) CHEK2 variants associate with hereditary prostate cancer. Br. J. Cancer, 89, 1966-1970.
    • (2003) Br. J. Cancer , vol.89 , pp. 1966-1970
    • Seppala, E.H.1
  • 12
    • 18444379055 scopus 로고    scopus 로고
    • A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer
    • Vahteristo,P. et al. (2002) A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer. Am. J. Hum. Genet., 71, 432-438.
    • (2002) Am. J. Hum. Genet , vol.71 , pp. 432-438
    • Vahteristo, P.1
  • 13
    • 33751202144 scopus 로고    scopus 로고
    • A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer
    • Cybulski,C. et al. (2006) A large germline deletion in the Chek2 kinase gene is associated with an increased risk of prostate cancer. J. Med. Genet., 43, 863-866.
    • (2006) J. Med. Genet , vol.43 , pp. 863-866
    • Cybulski, C.1
  • 14
    • 33847163983 scopus 로고    scopus 로고
    • A deletion in CHEK2 of 5395 basepairs predisposes to breast cancer in Poland
    • Cybulski,C. et al. (2006) A deletion in CHEK2 of 5395 basepairs predisposes to breast cancer in Poland. Breast Cancer Res. Treat, 102, 119-122.
    • (2006) Breast Cancer Res. Treat , vol.102 , pp. 119-122
    • Cybulski, C.1
  • 15
    • 33846307448 scopus 로고    scopus 로고
    • Germline CHEK2 mutations and colorectal cancer risk: Different effects of amissense and truncating mutations?
    • Cybulski,C. et al. (2007) Germline CHEK2 mutations and colorectal cancer risk: Different effects of amissense and truncating mutations? Eur. J. Hum. Genet., 15, 237-241.
    • (2007) Eur. J. Hum. Genet , vol.15 , pp. 237-241
    • Cybulski, C.1
  • 16
    • 33746830882 scopus 로고    scopus 로고
    • CHEK2 Il57T associates with familial and sporadic colorectal cancer
    • Kilpivaara,O. et al. (2006) CHEK2 Il57T associates with familial and sporadic colorectal cancer. J. Med. Genet., 43, e34.
    • (2006) J. Med. Genet , vol.43
    • Kilpivaara, O.1
  • 17
    • 34547851812 scopus 로고    scopus 로고
    • Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: Case-control study
    • Brennan,P. et al. (2007) Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: Case-control study. Hum. Mol. Genet., 16, 1794-1801.
    • (2007) Hum. Mol. Genet , vol.16 , pp. 1794-1801
    • Brennan, P.1
  • 18
    • 33645084562 scopus 로고    scopus 로고
    • Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer
    • Walsh,T. et al. (2006) Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. JAMA, 295, 1379-1388.
    • (2006) JAMA , vol.295 , pp. 1379-1388
    • Walsh, T.1
  • 19
    • 36448973875 scopus 로고    scopus 로고
    • CHK2 kinase: Cancer susceptibility and cancer therapy - two sides of the same coin?
    • Antoni,L. et al. (2007) CHK2 kinase: Cancer susceptibility and cancer therapy - two sides of the same coin? Nat. Rev. Cancer, 7, 925-936.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 925-936
    • Antoni, L.1
  • 20
    • 0033591845 scopus 로고    scopus 로고
    • Tobacco smoke carcinogens and lung cancer
    • Hecht,S.S. (1999) Tobacco smoke carcinogens and lung cancer. J. Natl Cancer Inst., 91, 1194-1210.
    • (1999) J. Natl Cancer Inst , vol.91 , pp. 1194-1210
    • Hecht, S.S.1
  • 21
    • 20444480258 scopus 로고    scopus 로고
    • TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: Distinct patterns in never, former, and current smokers
    • Le Calvez,F. et al. (2005) TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: Distinct patterns in never, former, and current smokers. Cancer Res., 65, 5076-5083.
    • (2005) Cancer Res , vol.65 , pp. 5076-5083
    • Le Calvez, F.1
  • 22
    • 34250837538 scopus 로고    scopus 로고
    • Patterns of EGFR, HER2, TP53, and, KRAS mutations of p14arf expression in non-small. cell lung cancers in relation to smoking history
    • Mounawar,M. et al. (2007) Patterns of EGFR, HER2, TP53, and, KRAS mutations of p14arf expression in non-small. cell lung cancers in relation to smoking history. Cancer Res., 67, 5667-5672.
    • (2007) Cancer Res , vol.67 , pp. 5667-5672
    • Mounawar, M.1
  • 23
    • 7044224706 scopus 로고    scopus 로고
    • Mutational spectrum of p53 mutations in primary breast and ovarian tumors
    • Feki,A. et al. (2004) Mutational spectrum of p53 mutations in primary breast and ovarian tumors. Crit. Rev. Oncol. Hematol., 52, 103-116.
    • (2004) Crit. Rev. Oncol. Hematol , vol.52 , pp. 103-116
    • Feki, A.1
  • 24
    • 1542725073 scopus 로고    scopus 로고
    • Targeting the checkpoint kinases: Chemosensitization versus chemoprotection
    • Zhou,B.B. et al. (2004) Targeting the checkpoint kinases: chemosensitization versus chemoprotection. Nat. Rev. Cancer, 4 216-225.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 216-225
    • Zhou, B.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.