-
1
-
-
0033651380
-
Polycyclic aromatic hydrocarbon levels and mutagenicity of inhalable particulate matter in Santiago, Chile
-
ADONIS M, GIL L (2000) Polycyclic aromatic hydrocarbon levels and mutagenicity of inhalable particulate matter in Santiago, Chile. Inhal Toxicol 12: 1173-83
-
(2000)
Inhal Toxicol
, vol.12
, pp. 1173-1183
-
-
ADONIS, M.1
GIL, L.2
-
2
-
-
33646022264
-
Evaluación de hipermetilación del gen p16INK4 - en cáncer escamoso de pulmón en pacientes chilenos
-
ADONIS W, AGUAYO F, CORDERO E, RODRÍGUEZ L, CASTILLO D and GUZMÁN L (2006). Evaluación de hipermetilación del gen p16INK4 - en cáncer escamoso de pulmón en pacientes chilenos, Rev Ch Enf Resp, 22: 7-12
-
(2006)
Rev Ch Enf Resp
, vol.22
, pp. 7-12
-
-
ADONIS, W.1
AGUAYO, F.2
CORDERO, E.3
RODRÍGUEZ, L.4
CASTILLO, D.5
GUZMÁN, L.6
-
3
-
-
0032578509
-
Aberrant methylation of p16 (INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
-
BELINSKY SA, NIKULA KJ, PALMISANO WA, MICHELS R, SACCOMANNO G, GABRIELSON E, BAYLIN SB, HERMAN JG (1998) Aberrant methylation of p16 (INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci U S A 95: 11891-11896
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11891-11896
-
-
BELINSKY, S.A.1
NIKULA, K.J.2
PALMISANO, W.A.3
MICHELS, R.4
SACCOMANNO, G.5
GABRIELSON, E.6
BAYLIN, S.B.7
HERMAN, J.G.8
-
4
-
-
0036119616
-
Aberrant CpG island methylation of the p16(INK4a) and estrogen receptor genes in rat lung tumours induced by particulate carcinogens
-
BELINSKY SA, SNOW SS, NIKULA KJ, FINCH GL, TELLEZ CS, PALMISANO WA (2002) Aberrant CpG island methylation of the p16(INK4a) and estrogen receptor genes in rat lung tumours induced by particulate carcinogens. Carcinogenesis 23: 335-339
-
(2002)
Carcinogenesis
, vol.23
, pp. 335-339
-
-
BELINSKY, S.A.1
SNOW, S.S.2
NIKULA, K.J.3
FINCH, G.L.4
TELLEZ, C.S.5
PALMISANO, W.A.6
-
5
-
-
4544250024
-
Gene-promoter hypermethylation as a biomarker in lung cancer
-
BELINSKY SA (2004) Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 4: 707-717
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 707-717
-
-
BELINSKY, S.A.1
-
6
-
-
33645521023
-
Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort
-
BELINSKY SA, LIECHTY KC, GENTRY FD, WOLF HJ, ROGERS J, VU K, HANEY J, KENNEDY TC, HIRSCH FR, MILLER Y, FRANKLIN WA, HERMAN JG, BAYLIN SB, BUNN PA, BYERS T (2006) Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res 66: 3338-3344
-
(2006)
Cancer Res
, vol.66
, pp. 3338-3344
-
-
BELINSKY, S.A.1
LIECHTY, K.C.2
GENTRY, F.D.3
WOLF, H.J.4
ROGERS, J.5
VU, K.6
HANEY, J.7
KENNEDY, T.C.8
HIRSCH, F.R.9
MILLER, Y.10
FRANKLIN, W.A.11
HERMAN, J.G.12
BAYLIN, S.B.13
BUNN, P.A.14
BYERS, T.15
-
7
-
-
34247217491
-
Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum
-
BELINSKY SA, GRIMES MJ, CASAS E, STIDLEY CA, FRANKLIN WA, BOCKLAGE TJ, JOHNSON DH, SCHILLER JH (2007) Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum. Br J Cancer 96: 1278-1283
-
(2007)
Br J Cancer
, vol.96
, pp. 1278-1283
-
-
BELINSKY, S.A.1
GRIMES, M.J.2
CASAS, E.3
STIDLEY, C.A.4
FRANKLIN, W.A.5
BOCKLAGE, T.J.6
JOHNSON, D.H.7
SCHILLER, J.H.8
-
8
-
-
33746407333
-
The emerging science of epigenomics
-
CALLINAN PA, FEINBERG AP (2006) The emerging science of epigenomics. Hum Mol Genet 15 Spec No 1: R95-101
-
(2006)
Hum Mol Genet
, vol.15
, Issue.SPEC 1
-
-
CALLINAN, P.A.1
FEINBERG, A.P.2
-
9
-
-
33845466236
-
Lung cancer risk prediction: A tool for early detection
-
CASSIDY A, DUFFY SW, MYLES JP, LILOGLOU T, FIELD JK (2007) Lung cancer risk prediction: a tool for early detection. Int J Cancer 120: 1-6
-
(2007)
Int J Cancer
, vol.120
, pp. 1-6
-
-
CASSIDY, A.1
DUFFY, S.W.2
MYLES, J.P.3
LILOGLOU, T.4
FIELD, J.K.5
-
10
-
-
17944390807
-
Optimisation of DNA and RNA extraction from archival formalin-fixed tissue
-
COOMBS NJ, GOUGH AC, PRIMROSE JN (1999) Optimisation of DNA and RNA extraction from archival formalin-fixed tissue. Nucleic Acids Res 27: e12
-
(1999)
Nucleic Acids Res
, vol.27
-
-
COOMBS, N.J.1
GOUGH, A.C.2
PRIMROSE, J.N.3
-
11
-
-
20344405446
-
DNA methylation disturbances as novel therapeutic target in lung cancer: Preclinical and clinical results
-
DIGEL W, LUBBERT M (2005) DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results. Crit Rev Oncol Hematol 55: 1-11
-
(2005)
Crit Rev Oncol Hematol
, vol.55
, pp. 1-11
-
-
DIGEL, W.1
LUBBERT, M.2
-
12
-
-
0037068312
-
CpG island hypermethylation and tumour suppressor genes: A booming present, a brighter future
-
ESTELLER M (2002) CpG island hypermethylation and tumour suppressor genes: a booming present, a brighter future. Oncogene 21: 5427-5440
-
(2002)
Oncogene
, vol.21
, pp. 5427-5440
-
-
ESTELLER, M.1
-
13
-
-
0141645511
-
Cancer epigenetics: DNA methylation and chromatin alterations in human cancer
-
ESTELLER M (2003) Cancer epigenetics: DNA methylation and chromatin alterations in human cancer. Adv Exp Med Biol 532: 39-49
-
(2003)
Adv Exp Med Biol
, vol.532
, pp. 39-49
-
-
ESTELLER, M.1
-
14
-
-
0036133873
-
Improvement of the methylation specific PCR technical conditions for the detection of p16 promoter hypermethylation in small amounts of tumour DNA
-
FAN X, INDA MM, TUÑON T AND CASTRESANA JS (2002) Improvement of the methylation specific PCR technical conditions for the detection of p16 promoter hypermethylation in small amounts of tumour DNA. Oncol Rep 9: 181-183
-
(2002)
Oncol Rep
, vol.9
, pp. 181-183
-
-
FAN, X.1
INDA, M.M.2
TUÑON, T.3
CASTRESANA, J.S.4
-
15
-
-
0033658109
-
Trends of polycyclic aromatic hydrocarbon levels and mutagenicity in Santiago's inhalable airborne particles in the period 1992-1996.Inhal
-
GIL L, KING L, ADONIS M (2000) Trends of polycyclic aromatic hydrocarbon levels and mutagenicity in Santiago's inhalable airborne particles in the period 1992-1996.Inhal Toxicol 12: 1185-204
-
(2000)
Toxicol
, vol.12
, pp. 1185-1204
-
-
GIL, L.1
KING, L.2
ADONIS, M.3
-
16
-
-
0035114558
-
-
GREENLEE RT, HILL-HARMON MB, MURRAY T AND THUN M (2001) Cancer statistics, 2001. CA Cancer J Clin 51: 15-36. Erratum in: CA Cancer J Clin 2001;51: 144
-
GREENLEE RT, HILL-HARMON MB, MURRAY T AND THUN M (2001) Cancer statistics, 2001. CA Cancer J Clin 51: 15-36. Erratum in: CA Cancer J Clin 2001;51: 144
-
-
-
-
17
-
-
0033591845
-
Tobacco smoke carcinogens and lung cancer
-
HECHT SS. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91: 1194-1210
-
J Natl Cancer Inst
, vol.91
, pp. 1194-1210
-
-
HECHT, S.S.1
-
18
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
HERMAN JG, MERLO A, MAO L, LAPIDUS RG, ISSA JP, DAVIDSON NE, SIDRANSKY D, BAYLIN SB (1995) Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 55: 4525-30
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
HERMAN, J.G.1
MERLO, A.2
MAO, L.3
LAPIDUS, R.G.4
ISSA, J.P.5
DAVIDSON, N.E.6
SIDRANSKY, D.7
BAYLIN, S.B.8
-
19
-
-
0029843950
-
Methylation -specific PCR: A novel PCR assay for methylation status of CpG islands
-
HERMAN JG, GRAFF JR, MYÖHÄNEN S, NELKIN BD AND BAYLIN SB (1996) Methylation -specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. USA 93: 9821-9826
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9821-9826
-
-
HERMAN, J.G.1
GRAFF, J.R.2
MYÖHÄNEN, S.3
NELKIN, B.D.4
BAYLIN, S.B.5
-
20
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
HERMAN JG, BAYLIN SB (2003) Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349: 2042-2054
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
HERMAN, J.G.1
BAYLIN, S.B.2
-
22
-
-
33646427172
-
Aberrant promoter methylation of p16 and MGMT genes in lung tumours from smoking and never-smoking lung cancer patients
-
LIU Y, LAN Q, SIEGFRIED JM, LUKETICH JD, KEOHAVONG P (2006) Aberrant promoter methylation of p16 and MGMT genes in lung tumours from smoking and never-smoking lung cancer patients. Neoplasia 8: 46-51
-
(2006)
Neoplasia
, vol.8
, pp. 46-51
-
-
LIU, Y.1
LAN, Q.2
SIEGFRIED, J.M.3
LUKETICH, J.D.4
KEOHAVONG, P.5
-
23
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
MERLO A, HERMAN JG, MAO L, LEE DJ, GABRIELSON E, BURGER PC, BAYLIN SB, SIDRANSKY D (1995) 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1: 686-692
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
MERLO, A.1
HERMAN, J.G.2
MAO, L.3
LEE, D.J.4
GABRIELSON, E.5
BURGER, P.C.6
BAYLIN, S.B.7
SIDRANSKY, D.8
-
24
-
-
25844465921
-
Epigenetic therapy of cancer with 5-aza-2′-deoxycytidine (decitabine)
-
MOMPARLER RL (2005) Epigenetic therapy of cancer with 5-aza-2′-deoxycytidine (decitabine). Semin Oncol 32: 443-451
-
(2005)
Semin Oncol
, vol.32
, pp. 443-451
-
-
MOMPARLER, R.L.1
-
25
-
-
33646343483
-
The methylation status and protein expression of CDH1, p16(INK4A), and fragile histidine triad in nonsmall cell lung carcinoma: Epigenetic silencing, clinical features, and prognostic significance
-
NAKATA S, SUGIO K, URAMOTO H, OYAMA T, HANAGIRI T, MORITA M, YASUMOTO K (2006) The methylation status and protein expression of CDH1, p16(INK4A), and fragile histidine triad in nonsmall cell lung carcinoma: epigenetic silencing, clinical features, and prognostic significance. Cancer 106: 2190-2199
-
(2006)
Cancer
, vol.106
, pp. 2190-2199
-
-
NAKATA, S.1
SUGIO, K.2
URAMOTO, H.3
OYAMA, T.4
HANAGIRI, T.5
MORITA, M.6
YASUMOTO, K.7
-
26
-
-
0033607147
-
In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
-
NUOVO GJ, PLAIA TW, BELINSKY SA, BAYLIN SB, HERMAN JG (1999) In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. Proc Natl Acad Sci USA 96: 12754-12759
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12754-12759
-
-
NUOVO, G.J.1
PLAIA, T.W.2
BELINSKY, S.A.3
BAYLIN, S.B.4
HERMAN, J.G.5
-
27
-
-
0036132096
-
Estimates of the world-wide prevalence of cancer for 25 sites in the adult population
-
PISANI P, BRAY F, PARKIN DM (2002) Estimates of the world-wide prevalence of cancer for 25 sites in the adult population. Int J Cancer 97: 72-81
-
(2002)
Int J Cancer
, vol.97
, pp. 72-81
-
-
PISANI, P.1
BRAY, F.2
PARKIN, D.M.3
-
28
-
-
0041438629
-
Promoter hypermethylation of the 06-methylguanine-DNA methyltransferase gene: More common in lung adenocarcinomas from never-smokers than smokers and associated with tumour progression
-
PULLING LC, DIVINE KK, KLINGE DM, GILLILAND FD, KANG T, SCHWARTZ AG, BOCKLAGE TJ, BELINSKY SA (2003) Promoter hypermethylation of the 06-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumour progression. Cancer Res 63: 4842-4848
-
(2003)
Cancer Res
, vol.63
, pp. 4842-4848
-
-
PULLING, L.C.1
DIVINE, K.K.2
KLINGE, D.M.3
GILLILAND, F.D.4
KANG, T.5
SCHWARTZ, A.G.6
BOCKLAGE, T.J.7
BELINSKY, S.A.8
-
29
-
-
0035266379
-
Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers
-
SANCHEZ-CESPEDES M, DECKER PA, DOFFEK KM, ESTELLER M, WESTRA WH, ALAWI EA, HERMAN JG, DEMEURE MJ, SIDRANSKY D, AHRENDT SA (2001) Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers. Cancer Res 61: 2092-2096
-
(2001)
Cancer Res
, vol.61
, pp. 2092-2096
-
-
SANCHEZ-CESPEDES, M.1
DECKER, P.A.2
DOFFEK, K.M.3
ESTELLER, M.4
WESTRA, W.H.5
ALAWI, E.A.6
HERMAN, J.G.7
DEMEURE, M.J.8
SIDRANSKY, D.9
AHRENDT, S.A.10
-
30
-
-
0037037790
-
Molecular epidemiology of smoking and lung cancer
-
SHIELDS PG (2002) Molecular epidemiology of smoking and lung cancer. Oncogene 21: 6870-6876
-
(2002)
Oncogene
, vol.21
, pp. 6870-6876
-
-
SHIELDS, P.G.1
-
31
-
-
12344321010
-
Epidemiological analysis of mortality caused by solid tumours in the Metropolitan Region, Chile, 1999
-
SZOT J (2003) Epidemiological analysis of mortality caused by solid tumours in the Metropolitan Region, Chile, 1999. Rev Med Chil 131: 641-9
-
(2003)
Rev Med Chil
, vol.131
, pp. 641-649
-
-
SZOT, J.1
-
32
-
-
12744280715
-
Loss of function of p16 gene and prognosis of pulmonary adenocarcinoma
-
TANAKA R, WANG D, MORISHITA Y, INADOME Y, MINAMI Y, IIJIMA T, FUKAI S, GOYA T, NOGUCHI M (2005) Loss of function of p16 gene and prognosis of pulmonary adenocarcinoma. Cancer 103: 608-615
-
(2005)
Cancer
, vol.103
, pp. 608-615
-
-
TANAKA, R.1
WANG, D.2
MORISHITA, Y.3
INADOME, Y.4
MINAMI, Y.5
IIJIMA, T.6
FUKAI, S.7
GOYA, T.8
NOGUCHI, M.9
-
33
-
-
0037220167
-
The TP53 gene, tobacco exposure, and lung cancer
-
TOYOOKA S, TSUDA T, GAZDAR AF (2003). The TP53 gene, tobacco exposure, and lung cancer. Hum Mutat 2: 229-239
-
(2003)
Hum Mutat
, vol.2
, pp. 229-239
-
-
TOYOOKA, S.1
TSUDA, T.2
GAZDAR, A.F.3
-
34
-
-
29244484904
-
Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart: World Health Organization. Classification of Tumours
-
Travis WD, Brambilla E, Muller-Hermelink Hk and Harris Cc (eds, International Agency for Research on Cancer IARC, Lyon, pp
-
TRAVIS WD, BRAMBILLA E, MULLER-HERMELINK HK AND HARRIS CC (2004) Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart: World Health Organization. Classification of Tumours. Pathology & Genetics. Travis WD, Brambilla E, Muller-Hermelink Hk and Harris Cc (eds). International Agency for Research on Cancer (IARC): Lyon, pp. 9-124
-
(2004)
Pathology & Genetics
, pp. 9-124
-
-
TRAVIS, W.D.1
BRAMBILLA, E.2
MULLER-HERMELINK, H.K.3
HARRIS, C.C.4
-
35
-
-
33750900241
-
Retinoblastoma regulatory pathway in lung cancer
-
WIKENHEISER-BROKAMP KA (2006) Retinoblastoma regulatory pathway in lung cancer. Curr Mol Med 6: 783-793
-
(2006)
Curr Mol Med
, vol.6
, pp. 783-793
-
-
WIKENHEISER-BROKAMP, K.A.1
-
36
-
-
0037152658
-
Smoking molecular damage in bronchial epithelium
-
WISTUBA II, MAO L AND GAZDAR AF (2002) Smoking molecular damage in bronchial epithelium. Oncogene 21: 7298-7306
-
(2002)
Oncogene
, vol.21
, pp. 7298-7306
-
-
WISTUBA II, M.L.1
GAZDAR, A.F.2
-
37
-
-
33847310768
-
Genetics of preneoplasia: Lessons from lung cancer
-
WISTUBA II (2007) Genetics of preneoplasia: lessons from lung cancer. Curr Mol Med 7: 3-14
-
(2007)
Curr Mol Med
, vol.7
, pp. 3-14
-
-
WISTUBA II1
-
38
-
-
0035132145
-
Aberrant promoter methylation of multiple genes in non-small cell lung cancers
-
ZOCHBAUER-MULLER S, FONG KM, VIRMANI AK, GERADTS J, GAZDAR AF, MINNA J (2001) Aberrant promoter methylation of multiple genes in non-small cell lung cancers. Cancer Res 61: 249-255
-
(2001)
Cancer Res
, vol.61
, pp. 249-255
-
-
ZOCHBAUER-MULLER, S.1
FONG, K.M.2
VIRMANI, A.K.3
GERADTS, J.4
GAZDAR, A.F.5
MINNA, J.6
|