Design and synthesis of 4-substituted indolo[3,2-e][1,2,3]triazolo[1,5-a] pyrimidine derivatives with antitumor activity

Journal of Medicinal Chemistry

Volumn 51, Issue 7, 2008, Pages 2037-2046

  Lauria, Antonino ^a   Patella, Chiara ^a   Dattolo, Gaetano ^a   Almerico, Anna Maria ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CYTOSINE; DNA FRAGMENT; GUANINE; INDOLO[3,2 E][1,2,3]TRIAZOLO[1,5 A]PYRIMIDINE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CENTRAL NERVOUS SYSTEM; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOLECULAR DOCKING; SUBSTITUTION REACTION;

ANTINEOPLASTIC AGENTS; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIMIDINONES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 41849096342     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm700964u     Document Type: Article

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