Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptane

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 7, 2008, Pages 3557-3564

  Bissel, Philippe ^a   Khalil, Ashraf ^a   Rimoldi, John M ^b   Igarashi, Kazuo ^a   Edmondson, Dale ^c   Miller, Anthony ^a   Castagnoli Jr , Neal ^a,d  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c EMORY UNIVERSITY   (United States)

^d EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

Cyclopropyl analog of MPTP; Diastereoselectivity; Enantioselectivity; Monoamine oxidase B

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; HEPTANE DERIVATIVE;

ARTICLE; CATALYST; CORRELATION ANALYSIS; ENZYMOLOGY; HUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS;

BICYCLO COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MONOAMINE OXIDASE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 41849092342     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.02.014     Document Type: Article

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