Neocortical microenvironment in patients with intractable epilepsy: Potassium and chloride concentrations

Epilepsia

Volumn 47, Issue 2, 2006, Pages 297-310

  Gorji, Ali ^a   Stemmer, Nina ^a   Rambeck, Bernhard ^b   Jürgens, Uwe ^b   May, Theodor ^b   Pannek, Heinz Wolfgang ^c   Behne, Friedrich ^c   Ebner, Alois ^c   Straub, Hiedrun ^a   Speckmann, Erwin Josef ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b Biochemical Laboratory   (Germany)

^c EPILEPSY CENTER BETHEL   (Germany)

Author keywords

Drug resistance; Intractable epilepsy; Ion homeostasis; Seizure

Indexed keywords

CHLORIDE; POTASSIUM;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DIALYSATE; DISEASE PREDISPOSITION; ELECTROCORTICOGRAPHY; ELECTROSTIMULATION; EPILEPTIC FOCUS; EPILEPTOGENESIS; FEMALE; HUMAN; IN VIVO STUDY; INTRACTABLE EPILEPSY; MALE; MICRODIALYSIS; MICROELECTRODE; MICROENVIRONMENT; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ADOLESCENT; ADULT; ANTICONVULSANTS; BRAIN CHEMISTRY; CHLORIDES; DRUG RESISTANCE; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; EPILEPSY; EXTRACELLULAR SPACE; FEMALE; HUMANS; INTRAOPERATIVE PERIOD; ION-SELECTIVE ELECTRODES; MAGNETIC RESONANCE IMAGING; MALE; MICRODIALYSIS; MICROELECTRODES; MIDDLE AGED; NEOCORTEX; POTASSIUM; TEMPORAL LOBE; TISSUE DISTRIBUTION;

EID: 33645288862     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2006.00421.x     Document Type: Article

References (59)

1. Lux HD Heinemann U Dietzel I. Ionic changes and alterations in the size of the extracellular space during epileptic activity. Adv Neurol 1986 44 619 639.
2. Kofuji P Newman EA. Potassium buffering in the central nervous system. Neuroscience 2004 129 1045 1056.
3. Pedley TA Fisher RS Futamachi KJ et al. Regulation of extracellular potassium concentration in epileptogenesis. Fed Proc 1976 35 1254 1259.
4. + homeostasis and altered electrophysiological properties of post-traumatic hippocampal glia. J Neurosci 1999 19 8152 8162.
5. Gorji A Kohling R Straub H et al. Lowering the extracellular potassium concentration elicits epileptic activity in neocortical tissue of epileptic patients. Eur J Neurosci. 2001 13 639 640.
6. Gorji A Madeja M Straub H et al. Lowering of the potassium concentration induces epileptiform activity in guinea-pig hippocampal slices. Brain Res 2001 908 130 139.
7. McBain CJ Traynelis SF Dingledine R et al. Epilepsy: Models, Mechanisms, and Concepts. Cambridge Cambridge University Press 1993 437 461.
8. Moddel G Gorji A Speckmann EJ. Background potassium concentrations and epileptiform discharges, I: electrophysiological characteristics of neuronal activity. Brain Res 2003 959 135 148.
9. Jentsch TJ Stein V Weinreich F et al. Molecular structure and physiological function of chloride channels. Physiol Rev 2002 82 503 568.
10. Treiman DM. GABAergic mechanisms in epilepsy. Epilepsia 2001 42 suppl 3 8 12.
11. Cohen I Navarro V Le Duigou C et al. Mesial temporal lobe epilepsy: a pathological replay of developmental mechanisms¿ Biol Cell 2003 95 329 333.
12. Benveniste H Huttemeier PC. Microdialysis: theory and application. Prog Neurobiol 1990 35 195 215.
13. Kohling R Lucke A Straub H et al. Spontaneous sharp waves in human neocortical slices excised from epileptic patients. Brain 1998 121 1073 1087.
14. Gorji A Hohling JM Madeja M et al. Effect of levetiracetam on epileptiform discharges in human neocortical slices. Epilepsia 2003 43 1480 1487.
15. Gorji A Speckmann EJ. Spreading depression enhances the spontaneous epileptiform activity in human neocortical tissues. Eur J Neurosci 2004 19 3371 3374.
16. Viukari NM. Low potassium levels in the cerebrospinal fluid of forty mentally subnormal epileptics. J Ment Defic Res 1970 14 191 195.
17. Kiviranta T Tuomisto L Airaksinen EM. Osmolality and electrolytes in cerebrospinal fluid and serum of febrile children with and without seizures. Eur J Pediatr 1996 155 120 125.
18. Reinert M Khaldi A Zauner A et al. High level of extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure. J Neurosurg 2000 93 800 807.
19. Reinstrup P Stahl N Mellergard P et al. Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anaesthesia, and neurosurgery. Neurosurgery 2000 47 701 710.
20. Hutchinson PJ O'Connel MT Al-Rawi PG et al. Clinical cerebral microdialysis: a methodological study. J Neurosurg 2000 93 37 43.
21. Stemmer N. Die Epileptologenese bei Hirntumoren: Verteilung des extrazellulären Mikromilieus im Tumorbereich. Diplomarbeit Doctoral Thesis WWU Münster, Universität Bielefeld 2004.
22. Speckmann EJ Caspers H. Fortlaufende Registrierung des Sauerstoffdrucks an der Hirnrinde der Ratte. Beckmann Rep 1967 4 3 5.
23. Speckmann EJ Caspers H. Verschibungen des corticalen Bestandpotentials bei Verhanderungen der Ventilationsgröße. Pflügers Arch 1969 310 235 250.
24. Zuckermann EC Glaser GH. Hippocampal epileptic activity induced by localized ventricular perfusion with high-potassium cerebrospinal fluid. Exp Neurol 1968 20 87 110.
25. Yaari Y Konnerth A Heinemann U. Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro, II: role of extracellular potassium. J Neurophysiol 1986 56 424 438.
26. Traynelis SF Dingledine R. Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice. J Neurophysiol 1988 59 259 276.
27. Izquierdo I. Hippocampal physiology: experiments on regulation of its electrical activity, on the mechanism of seizures, and on a hypothesis of learning. Behav Biol 1972 7 669 698.
28. A-mediated inhibition and in vitro epileptogenesis in the human neocortex. J Neurophysiol 1995 73 468 484.
29. Hoppe D Chvatal A Kettenmann H et al. Characteristics of activity-dependent potassium accumulation in mammalian peripheral nerve in vitro. Brain Res 1991 552 106 112.
30. Walz W. Role of astrocytes in the clearance of excess extracellular potassium. Neurochem Int 2000 36 291 300.
31. o in human epileptic non-sclerotic and sclerotic hippocampal area CA1. Eur J Neurosci 2000 12 2039 2048.
32. Heinemann U Gabriel S Jauch R et al. Alterations of glial cell function in temporal lobe epilepsy. Epilepsia 2000 41 suppl 6 S185 S189.
33. Newman EA. Regional specialization of retinal glial cell membrane. Nature 1984 309 155 157.
34. Ballanyi K Grafe P ten Bruggencate G. Ion activities and potassium uptake mechanisms of glial cells in guinea-pig olfactory cortex slices. J Physiol 1987 382 159 174.
35. + uptake in glia prevents long-term depression maintenance and causes epileptiform activity. J Neurosci 1997 17 2813 2824.
36. + in rat hippocampus. J Neurophysiol 2002 l;87 87 102.
37. +-ATPase in bulk isolated glial cells and synaptosomes. Brain Res 1986 364 1 11.
38. Bordey A Sontheimer H. Properties of human glial cells associated with epileptic seizure foci. Epilepsy Res 1998 32 286 303.
39. Kendal C Everall I Polkey C et al. Glial cell changes in the white matter in temporal lobe epilepsy. Epilepsy Res 1999 36 43 51.
40. Spencer SS Kim J deLanerolle N et al. Differential neuronal and glial relations with parameters of ictal discharge in mesial temporal lobe epilepsy. Epilepsia 1999 40 708 712.
41. o and field potentials in dentate gyrus and area CA1 of human epileptic hippocampus. Neurosci Lett 1998 249 91 94.
42. Hinterkeuser S Schroder W Hager G et al. Astrocytes in the hippocampus of patients with temporal lobe epilepsy display changes in potassium conductances. Eur J Neurosci 2000 12 2087 2096.
43. Schroder W Hinterkeuser S Seifert G et al. Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy. Epilepsia 2000 41 suppl 6 S181 S184.
44. Yamamoto C Kawai N. Seizure discharges evoked in vitro in thin section from guinea pig hippocampus. Science 1967 155 341 342.
45. Avoli M Drapeau C Perreault P et al. Epileptiform activity induced by low chloride medium in the CA1 subfield of the hippocampal slice. J Neurophysiol 1990 64 1747 1757.
46. Misgeld U Deisz RA Dodt HU et al. The role of chloride transport in postsynaptic inhibition of hippocampal neurons. Science 1986 232 1413 1415.
47. Thompson SM Deisz RA Prince DA. Relative contributions of passive equilibrium and active transport to the distribution of chloride in mammalian cortical neurons. J Neurophysiol 1988 60 105 124.
48. Thompson SM Gahwiler BH. Activity-dependent disinhibition, II. effects of extracellular potassium, furosemide, and membrane potential on ECl- in hippocampal CA3 neurons. J Neurophysiol 1989 61 512 523.
49. Thompson SM. Modulation of inhibitory synaptic transmission in the hippocampus. Prog Neurobiol 1994 42 575 609.
50. Schwartzkroin PA Prince DA. Changes in excitatory and inhibitory synaptic potentials leading to epileptogenic activity. Brain Res 1980 183 61 76.
51. Holthoff K Witte OW. Intrinsic optical signals in rat neocortical slices measured with near-infrared dark-field microscopy reveal changes in extracellular space. J Neurosci 1996 16 2740 2749.
52. MacVicar BA Hochman D. Imaging of synaptically evoked intrinsic optical signals in hippocampal slices. J Neurosci 1991 11 1458 1469.
53. Haug K Warnstedt M Alekov AK et al. Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies. Nat Genet 2003 33 527 532.
54. Aickin CC Deisz RA Lux HD. Ammonium action on post-synaptic inhibition in crayfish neurones: implications for the mechanism of chloride extrusion. J Physiol 1982 329 319 339.
55. Ishida R. Electroencephalographical studies on the seizure discharges induced by ammonium chloride in the rabbit. Jpn J Pharmacol 1967 17 6 18.
56. Payne JA Rivera C Voipio J et al. Cation-chloride co-transporters in neuronal communication, development and trauma. Trends Neurosci 2003 26 199 206.
57. - accumulation and depletion in cultured rat midbrain neurons. J Neurosci 1999 19 4695 704.
58. A receptors in acutely isolated pyramidal neurons of rat hippocampus. Neuropharmacology 1996 35 1279 1288.
59. Straub H Kuhnt U Hohling JM et al. Stimulus-induced patterns of bioelectric activity in human neocortical tissue recorded by a voltage sensitive dye. Neuroscience 2003 121 587 604.