메뉴 건너뛰기




Volumn 28, Issue 3, 2008, Pages 465-477

Norcantharidin ameliorates proteinuria, associated tubulointerstitial inflammation and fibrosis in protein overload nephropathy

Author keywords

Connective tissue growth factor; Fibrosis; Interstitial inflammation; Norcantharidin; Nuclear factor B; Proteinuria

Indexed keywords

BOVINE SERUM ALBUMIN; CONNECTIVE TISSUE GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NORCANTHARIDIN; SYNAPTOTAGMIN I;

EID: 41849085477     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000112850     Document Type: Article
Times cited : (32)

References (36)
  • 1
    • 33749432129 scopus 로고    scopus 로고
    • Relationship between clinical predictors and tubulointerstitial damage in adult-onset primary nephrotic syndrome
    • Liu FY, Li Y, Peng YM, Yang L, Duan SB, Li J, Chen X, Xia YC, Guo N, Xu XQ: Relationship between clinical predictors and tubulointerstitial damage in adult-onset primary nephrotic syndrome. Arch Med Res 2006;37:981-986.
    • (2006) Arch Med Res , vol.37 , pp. 981-986
    • Liu, F.Y.1    Li, Y.2    Peng, Y.M.3    Yang, L.4    Duan, S.B.5    Li, J.6    Chen, X.7    Xia, Y.C.8    Guo, N.9    Xu, X.Q.10
  • 2
    • 12144264180 scopus 로고    scopus 로고
    • Proteinuria and growth factors in the development of tubulointerstitial injury and scarring in kidney disease
    • Hirschberg R, Wang S: Proteinuria and growth factors in the development of tubulointerstitial injury and scarring in kidney disease. Curr Opin Nephrol Hypertens 2005;14:43-52.
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 43-52
    • Hirschberg, R.1    Wang, S.2
  • 3
    • 34250859407 scopus 로고    scopus 로고
    • Proteinuria as a therapeutic target in patients with chronic kidney disease
    • Palmer BF: Proteinuria as a therapeutic target in patients with chronic kidney disease. Am J Nephrol 2007;27:287-293.
    • (2007) Am J Nephrol , vol.27 , pp. 287-293
    • Palmer, B.F.1
  • 4
    • 0034618205 scopus 로고    scopus 로고
    • Anhydride modified cantharidin analogues: Synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activity
    • McCluskey A, Bowyer MC, Collins E, Sim ATR, Sakoff JA, Baldwin ML: Anhydride modified cantharidin analogues: synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activity. Bioorg Med Chem Lett 2000;10:1687-1690.
    • (2000) Bioorg Med Chem Lett , vol.10 , pp. 1687-1690
    • McCluskey, A.1    Bowyer, M.C.2    Collins, E.3    Sim, A.T.R.4    Sakoff, J.A.5    Baldwin, M.L.6
  • 5
    • 0036208532 scopus 로고    scopus 로고
    • Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues
    • Sakoff JA, Ackland SP, Baldwin ML, Keane MA, McCluskey A: Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues. Invest New Drugs 2002;20:1-11.
    • (2002) Invest New Drugs , vol.20 , pp. 1-11
    • Sakoff, J.A.1    Ackland, S.P.2    Baldwin, M.L.3    Keane, M.A.4    McCluskey, A.5
  • 7
    • 0037054929 scopus 로고    scopus 로고
    • Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells
    • Chen YN, Chen JC, Yin SC, Wang GS, Tsauer W, Hsu SF, Hsu SL: Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells. Int J Cancer 2002;100:158-165.
    • (2002) Int J Cancer , vol.100 , pp. 158-165
    • Chen, Y.N.1    Chen, J.C.2    Yin, S.C.3    Wang, G.S.4    Tsauer, W.5    Hsu, S.F.6    Hsu, S.L.7
  • 8
    • 0029034492 scopus 로고
    • Effects of norcantharidin, a protein phosphatase type-2A inhibitor, on the growth of normal and malignant haemopoietic cells
    • Liu XH, Blazsek I, Comisso M, Legras S, Marion S, Quittet P, Anjo A, Wang GS, Misset JL: Effects of norcantharidin, a protein phosphatase type-2A inhibitor, on the growth of normal and malignant haemopoietic cells. Eur J Cancer 1995;31A:953-963.
    • (1995) Eur J Cancer , vol.31 A , pp. 953-963
    • Liu, X.H.1    Blazsek, I.2    Comisso, M.3    Legras, S.4    Marion, S.5    Quittet, P.6    Anjo, A.7    Wang, G.S.8    Misset, J.L.9
  • 9
    • 0041624233 scopus 로고    scopus 로고
    • Structure-based design of a highly selective catalytic site-directed inhibitor of Ser/Thr protein phosphatase 2B (calcineurin)
    • Baba Y, Hirukawa N, Tanohira N, Sodeoka M: Structure-based design of a highly selective catalytic site-directed inhibitor of Ser/Thr protein phosphatase 2B (calcineurin). J Am Chem Soc 2003;125:9740-9749.
    • (2003) J Am Chem Soc , vol.125 , pp. 9740-9749
    • Baba, Y.1    Hirukawa, N.2    Tanohira, N.3    Sodeoka, M.4
  • 10
    • 0033867619 scopus 로고    scopus 로고
    • Interstitial fibrosis in mice with overload proteinuria: Deficiency of TIMP-1 is not protective
    • Eddy AA, Kim H, López-Guisa J, Oda T, Soloway PD: Interstitial fibrosis in mice with overload proteinuria: deficiency of TIMP-1 is not protective. Kidney Int 2000;58:618-628.
    • (2000) Kidney Int , vol.58 , pp. 618-628
    • Eddy, A.A.1    Kim, H.2    López-Guisa, J.3    Oda, T.4    Soloway, P.D.5
  • 11
    • 27744489524 scopus 로고    scopus 로고
    • Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy
    • Bonegio RG, Fuhro R, Wang Z, Valeri CR, Andry C, Salant DJ, Lieberthal W: Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy. J Am Soc Nephrol 2005;16:2063-2072.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2063-2072
    • Bonegio, R.G.1    Fuhro, R.2    Wang, Z.3    Valeri, C.R.4    Andry, C.5    Salant, D.J.6    Lieberthal, W.7
  • 12
    • 0035892777 scopus 로고    scopus 로고
    • High expression levels of nuclear factor kappaB, IkappaB kinase alpha and Akt kinase in squamous cell carcinoma of the oral cavity
    • Nakayama H, Ikebe T, Beppu M, Shirasuna K: High expression levels of nuclear factor kappaB, IkappaB kinase alpha and Akt kinase in squamous cell carcinoma of the oral cavity. Cancer 2001;92:3037-3044.
    • (2001) Cancer , vol.92 , pp. 3037-3044
    • Nakayama, H.1    Ikebe, T.2    Beppu, M.3    Shirasuna, K.4
  • 14
    • 33745188045 scopus 로고    scopus 로고
    • Combination therapy with an angiotensin receptor blocker and an ACE inhibitor in proteinuric renal disease: A systematic review of the efficacy and safety data
    • MacKinnon M, Shurraw S, Akbari A, Knoll GA, Jaffey J, Clark HD: Combination therapy with an angiotensin receptor blocker and an ACE inhibitor in proteinuric renal disease: a systematic review of the efficacy and safety data. Am J Kidney Dis 2006;48:8-20.
    • (2006) Am J Kidney Dis , vol.48 , pp. 8-20
    • MacKinnon, M.1    Shurraw, S.2    Akbari, A.3    Knoll, G.A.4    Jaffey, J.5    Clark, H.D.6
  • 15
    • 0038106471 scopus 로고    scopus 로고
    • ACE inhibitors and AT-1-receptor antagonists COOPERATE in non-diabetic renal disease
    • Doggrell SA: ACE inhibitors and AT-1-receptor antagonists COOPERATE in non-diabetic renal disease. Expert Opin Pharmacother 2003;4:1185-1188.
    • (2003) Expert Opin Pharmacother , vol.4 , pp. 1185-1188
    • Doggrell, S.A.1
  • 16
    • 0037431774 scopus 로고    scopus 로고
    • Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): A randomised controlled trial
    • Nakao N, Yoshimura A, Morita H, Takada M, Kayano T, Ideura T: Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): a randomised controlled trial. Lancet 2003;361:117-124.
    • (2003) Lancet , vol.361 , pp. 117-124
    • Nakao, N.1    Yoshimura, A.2    Morita, H.3    Takada, M.4    Kayano, T.5    Ideura, T.6
  • 17
    • 0036019479 scopus 로고    scopus 로고
    • Combination ACEI and ARB therapy: Additional benefit in renoprotection?
    • Taal MW, Brenner BM: Combination ACEI and ARB therapy: additional benefit in renoprotection? Curr Opin Nephrol Hypertens 2002;11:377-381.
    • (2002) Curr Opin Nephrol Hypertens , vol.11 , pp. 377-381
    • Taal, M.W.1    Brenner, B.M.2
  • 18
    • 0036239003 scopus 로고    scopus 로고
    • Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis
    • Ha IS, Um EY, Jung HR, Park HW, Cheong HI, Choi Y: Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis. Am J Kidney Dis 2002;39:1001-1010.
    • (2002) Am J Kidney Dis , vol.39 , pp. 1001-1010
    • Ha, I.S.1    Um, E.Y.2    Jung, H.R.3    Park, H.W.4    Cheong, H.I.5    Choi, Y.6
  • 20
    • 0038745634 scopus 로고    scopus 로고
    • In vitro anti-proliferation/cytotoxic activity of cantharidin (Spanish fly) and related derivatives
    • Williams LA, Moller W, Merisor E, Kraus W, Rosner H: In vitro anti-proliferation/cytotoxic activity of cantharidin (Spanish fly) and related derivatives. West Indian Med J 2003;52:10-13.
    • (2003) West Indian Med J , vol.52 , pp. 10-13
    • Williams, L.A.1    Moller, W.2    Merisor, E.3    Kraus, W.4    Rosner, H.5
  • 21
    • 0035927443 scopus 로고    scopus 로고
    • Potential new antitumor agents from an innovative combination of demethylcantharidin, a modified traditional Chinese medicine, with a platinum moiety
    • Ho YP, To KK, Au-Yeung SC, Wang X, Lin G, Han X: Potential new antitumor agents from an innovative combination of demethylcantharidin, a modified traditional Chinese medicine, with a platinum moiety. J Med Chem 2001;44:2065-2068.
    • (2001) J Med Chem , vol.44 , pp. 2065-2068
    • Ho, Y.P.1    To, K.K.2    Au-Yeung, S.C.3    Wang, X.4    Lin, G.5    Han, X.6
  • 23
    • 0030751395 scopus 로고    scopus 로고
    • Norcantharidin inhibits growth of human Hep G2 cell-transplanted tumor in nude mice and prolongs host survival
    • Yang EB, Tang WY, Zhang K, Cheng LY, Mack PO: Norcantharidin inhibits growth of human Hep G2 cell-transplanted tumor in nude mice and prolongs host survival. Cancer Lett 1997;117:93-98.
    • (1997) Cancer Lett , vol.117 , pp. 93-98
    • Yang, E.B.1    Tang, W.Y.2    Zhang, K.3    Cheng, L.Y.4    Mack, P.O.5
  • 24
    • 0026095943 scopus 로고
    • Inhibitory effect of norcantharidin on K562 human myeloid leukemia cells in vitro
    • Yi SN, Wass J, Vincent P, Iland H: Inhibitory effect of norcantharidin on K562 human myeloid leukemia cells in vitro. Leuk Res 1991;15:883-886.
    • (1991) Leuk Res , vol.15 , pp. 883-886
    • Yi, S.N.1    Wass, J.2    Vincent, P.3    Iland, H.4
  • 26
    • 1642455941 scopus 로고    scopus 로고
    • Proteinuria and its consequences in renal disease
    • Schieppati A, Remuzzi G: Proteinuria and its consequences in renal disease. Acta Paediatr Suppl 2003;92:9-13.
    • (2003) Acta Paediatr Suppl , vol.92 , pp. 9-13
    • Schieppati, A.1    Remuzzi, G.2
  • 28
    • 0031749820 scopus 로고    scopus 로고
    • Protein overload stimulates RANTES production by proximal tubular cells depending on NF-κB activation
    • Zoja C, Donadelli R, Colleoni S, Figliuzzi M, Bonazzola S, Morigi M, Remuzzi G: Protein overload stimulates RANTES production by proximal tubular cells depending on NF-κB activation. Kidney Int 1998;53:1608-1615.
    • (1998) Kidney Int , vol.53 , pp. 1608-1615
    • Zoja, C.1    Donadelli, R.2    Colleoni, S.3    Figliuzzi, M.4    Bonazzola, S.5    Morigi, M.6    Remuzzi, G.7
  • 29
    • 0032991086 scopus 로고    scopus 로고
    • Induction of monocyte chemoattractant protein-1 by albumin is mediated by nuclear factor κB in proximal tubule cells
    • Wang Y, Rangan GK, Tay Y-C, Wang Y, Harris DC: Induction of monocyte chemoattractant protein-1 by albumin is mediated by nuclear factor κB in proximal tubule cells. J Am Soc Nephrol 1999;10:1204-1213.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1204-1213
    • Wang, Y.1    Rangan, G.K.2    Tay, Y.-C.3    Wang, Y.4    Harris, D.C.5
  • 31
    • 0034744613 scopus 로고    scopus 로고
    • Activation of NF-κB in tubular epithelial cells of rats with intense proteinuria. Role of angiotensin II and endothelin-1
    • Gomez-Garre D, Largo R, Tejera N, Fortes J, Manzarbeitia F, Eqido J: Activation of NF-κB in tubular epithelial cells of rats with intense proteinuria. Role of angiotensin II and endothelin-1. Hypertension 2001;37:1171-1178.
    • (2001) Hypertension , vol.37 , pp. 1171-1178
    • Gomez-Garre, D.1    Largo, R.2    Tejera, N.3    Fortes, J.4    Manzarbeitia, F.5    Eqido, J.6
  • 32
    • 0347915577 scopus 로고    scopus 로고
    • CCN proteins: Multifunctional signalling regulators
    • Perbal B: CCN proteins: multifunctional signalling regulators. Lancet 2004;363:62-64.
    • (2004) Lancet , vol.363 , pp. 62-64
    • Perbal, B.1
  • 35
    • 34247566049 scopus 로고    scopus 로고
    • Cyclosporin A and tacrolimus (FK506) differentially alter T-cell receptor expression in vivo
    • Miller JL, Ericson SG: Cyclosporin A and tacrolimus (FK506) differentially alter T-cell receptor expression in vivo. Immunopharmacol Immunotoxicol 2007;29:105-118.
    • (2007) Immunopharmacol Immunotoxicol , vol.29 , pp. 105-118
    • Miller, J.L.1    Ericson, S.G.2
  • 36
    • 0027401133 scopus 로고
    • The preliminary observation on immuno-suppressive effect of norcantharidin in mice
    • Yan MS, Xiue S, Wei LX, Piao XH: The preliminary observation on immuno-suppressive effect of norcantharidin in mice. Immunopharmacol Immunotoxicol 1993;15:79-85.
    • (1993) Immunopharmacol Immunotoxicol , vol.15 , pp. 79-85
    • Yan, M.S.1    Xiue, S.2    Wei, L.X.3    Piao, X.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.