Regulation of C/EBPδ-dependent transactivation by histone deacetylases in intestinal epithelial cells

Journal of Cellular Biochemistry

Volumn 103, Issue 5, 2008, Pages 1573-1583

  Turgeon, Naomie ^a   Valiquette, Caroline ^a   Blais, Mylène ^a   Routhier, Sophie ^a   Seidman, Ernest G ^b   Asselin, Claude ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

C EBP ; Haptoglobin; Histone deacetylase; Inflammation; Intestinal epithelial cells

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN DELTA; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; HISTONE H3; HISTONE H4; INTERLEUKIN 1BETA; MESSENGER RNA; SHORT HAIRPIN RNA; HAPTOGLOBIN; HISTONE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; GENE EXPRESSION; GENE SILENCING; IMMUNOPRECIPITATION; INTESTINE CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; RAT; WESTERN BLOTTING; ACETYLATION; ACUTE PHASE RESPONSE; ANIMAL; BIOSYNTHESIS; CELL STRAIN CACO 2; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSCRIPTION; HUMAN; INTESTINE MUCOSA; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TRANSACTIVATION;

ACETYLATION; ACUTE-PHASE REACTION; ANIMALS; CACO-2 CELLS; CCAAT-ENHANCER-BINDING PROTEIN-DELTA; HAPTOGLOBINS; HISTONE DEACETYLASES; HISTONES; HUMANS; INTERLEUKIN-1BETA; INTESTINAL MUCOSA; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RNA, SMALL INTERFERING; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC;

EID: 41749111570     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21544     Document Type: Article

References (35)

1. Beaulieu JF, Quaroni A. 1991. Clonal analysis of sucrase-isomaltase expression in the human colon adenocarcinoma Caco-2 cells. Biochem J 280:599-608.
2. Blais M, Desilets A, Asselin C. 2005. Synergy between deacetylase inhibitors and IL-1beta in activation of the serum amyloid A2 gene promoter. DNA Cell Biol 24:209-217.
3. Boudreau F, Yu SJ, Asselin C. 1998. CCAAT/enhancer binding proteins beta and delta regulate alpha1-acid glycoprotein gene expression in rat intestinal epithelial cells. DNA Cell Biol 17:669-677.
4. Cao Z, Umek RM, McKnight SL. 1991. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev 5:1538-1552.
5. Chang EB. 2000. Inflammatory bowel diseases. In: Kirsner JB, editor. Intestinal epithelial function and response to mucosal injury in inflammatory bowel diseases. Philadelphia, PA: WB Saunders. pp 3-19.
6. Desilets A, Gheorghiu I, Yu SJ, Seidman EG, Asselin C. 2000. Inhibition by deacetylase inhibitors of IL-1-dependent induction of haptoglobin involves CCAAT/Enhancer-binding protein isoforms in intestinal epithelial cells. Biochem Biophys Res Commun 276:673-679.
7. Di-Poi N, Desvergne B, Michalik L, Wahli W. 2005. Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins. J Biol Chem 280:38700-38710.
8. Erickson RL, Hemati N, Ross SE, MacDougald OA. 2001. p300 coactivates the adipogenic transcription factor CCAAT/enhancer-binding protein alpha. J Biol Chem 276:16348-16355.
9. Gheorghiu I, Deschenes C, Blais M, Boudreau F, Rivard N, Asselin C. 2001. Role of specific CCAAT/enhancer-binding protein isoforms in intestinal epithelial cells. J Biol Chem 276:44331-44337.
10. Guo S, Cichy SB, He X, Yang Q, Ragland M, Ghosh AK, Johnson PF, Unterman TG. 2001. Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta. J Biol Chem 276:8516-8523.
11. Houde M, Laprise P, Jean D, Blais M, Asselin C, Rivard N. 2001. Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor C DX2. J Biol Chem 276:21885-21894.
12. Ki SH, Cho IJ, Choi DW, Kim SG. 2005. Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: Role of SMRT recruited to GR in GSTA2 gene repression. Mol Cell Biol 25:4150-4165.
13. Kovacs KA, Steinmann M, Magistretti PJ, Halfon O, Cardinaux JR. 2003. CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation. J Biol Chem 278:36959-36965.
14. Laprise P, Chailler P, Houde M, Beaulieu JF, Boucher MJ, Rivard N. 2002. Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation. J Biol Chem 277:8226-8234.
15. Marinkovic S, Baumann H. 1990. Structure, hormonal regulation, and identification of the interleukin-6- and dexamethasone-responsive element of the rat haptoglobin gene. Mol Cell Biol 10:1573-1583.
16. Mink S, Haenig B, Klempnauer KH. 1997. Interaction and functional collaboration of p300 and C/EBPbeta. Mol Cell Biol 17:6609-6617.
17. Pelletier N, Boudreau F, Yu SJ, Zannoni S, Boulanger V, Asselin C. 1998. Activation of haptoglobin gene expression by cAMP involves CCAAT/enhancer- binding protein isoforms in intestinal epithelial cells. FEBS Lett 439:275-280.
18. Perreault N, Jean-Francois B. 1996. Use of the dissociating enzyme thermolysin to generate viable human normal intestinal epithelial cell cultures. Exp Cell Res 224:354-364.
19. Poli V. 1998. The role of C/EBP isoforms in the control of inflammatory and native immunity functions. J Biol Chem 273:29279-29282.
20. Quaroni A, May RJ. 1980. Establishment and characterization of intestinal epithelial cell cultures. Methods Cell Biol 21B:403-427.
21. Ramji DP, Foka P. 2002. CCAAT/enhancer-binding proteins: Structure, function and regulation. Biochem J 365:561-575.
22. Sadowski I, Bell B, Broad P, Hollis M. 1992. GAL4 fusion vectors for expression in yeast or mammalian cells. Gene 118:137-141.
23. Silverstein RA, Ekwall K. 2005. Sin3: A flexible regulator of global gene expression and genome stability. Curr Genet 47:1-17.
24. Sivko GS, DeWille JW. 2004. CCAAT/Enhancer binding protein delta (c/EBPdelta) regulation and expression in human mammary epithelial cells: I. "Loss of function" alterations in the c/EBPdelta growth inhibitory pathway in breast cancer cell lines. J Cell Biochem 93:830-843.
25. Sivko GS, Sanford DC, Dearth LD, Tang D, DeWille JW. 2004. CCAAT/enhancer binding protein delta (c/EBP-delta) regulation and expression in human mammary epithelial cells. II. Analysis of activating signal transduction pathways, transcriptional, post-transcriptional, and post-translational control. J Cell Biochem 93:844-856.
26. Souleimani A, Asselin C. 1993. Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2. Biochem Biophys Res Commun 193:330-336.
27. Stein B, Rahmsdorf HJ, Steffen A, Litfin M, Herrlich P. 1989. UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein. Mol Cell Biol 9:5169-5181.
28. Svotelis A, Doyon G, Bernatchez G, Desilets A, Rivard N, Asselin C. 2005. IL-1 beta-dependent regulation of C/EBP delta transcriptional activity. Biochem Biophys Res Commun 328:461-470.
29. Tanaka T, Yoshida N, Kishimoto T, Akira S. 1997. Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO J 16:7432-7443.
30. Thangaraju M, Rudelius M, Bierie B, Raffeld M, Sharan S, Hennighausen L, Huang AM, Sterneck E. 2005. C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution. Development 132:4675-4685.
31. Vashisht Gopal YN, Arora TS, Van Dyke MW. 2006. Tumour necrosis factor-alpha depletes histone deacetylase 1 protein through I KK2. EMBO Rep 7:291-296.
32. Wilson AJ, Byun DS, Popova N, Murray LB, L'Italien K, Sowa Y, Arango D, Velcich A, Augenlicht LH, Mariadason JM. 2006. Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. J Biol Chem 281:13548-13558.
33. Wiper-Bergeron N, Wu D, Pope L, Schild-Poulter C, Hache RJ. 2003. Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex. EMBO J 22:2135-2145.
34. Yu SJ, Boudreau F, Desilets A, Houde M, Rivard N, Asselin C. 1999. Attenuation of haptoglobin gene expression by TGFbeta requires the MAP kinase pathway. Biochem Biophys Res Commun 259:544-549.
35. Zuo Y, Qiang L, Farmer SR. 2006. Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter. J Biol Chem 281:7960-7967.