Tl+-induced μs gating of current indicates instability of the MaxiK selectivity filter as caused by ion/pore interaction

Journal of General Physiology

Volumn 131, Issue 4, 2008, Pages 365-378

  Schroeder, Indra ^a   Hansen, Ulf Peter ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; THALLIUM; POTASSIUM;

ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC POTENTIAL; FILTER; HISTOGRAM; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MOLECULAR INTERACTION; PATCH CLAMP; PROTEIN FUNCTION; BINDING SITE; BIOLOGICAL MODEL; CELL LINE; CELL MEMBRANE POTENTIAL; CHEMISTRY; CYTOSOL; DOSE RESPONSE; DRUG EFFECT; ELECTRIC CONDUCTIVITY; KINETICS; METABOLISM; PHYSIOLOGY; PROBABILITY; STATISTICAL ANALYSIS; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CELL LINE, TRANSFORMED; CYTOSOL; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; HUMANS; ION CHANNEL GATING; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MARKOV CHAINS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; PATCH-CLAMP TECHNIQUES; POTASSIUM; STRUCTURE-ACTIVITY RELATIONSHIP; THALLIUM;

EID: 41749093800     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200809956     Document Type: Article

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