Contractile properties of the pig bladder mucosa in response to neurokinin A: A role for myofibroblasts?

British Journal of Pharmacology

Volumn 153, Issue 7, 2008, Pages 1465-1473

  Sadananda, P ^a   Chess Williams, R ^b   Burcher, E ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b BOND UNIVERSITY   (Australia)

Author keywords

Detrusor; Mucosa; Myofibroblasts; Neurokinin A; NK 2 receptor; Smooth muscle; Smooth muscle actin; SR48968; Urinary bladder; Urothelium

Indexed keywords

ACTIN; CARBACHOL; DESMIN; INDOMETACIN; NEUROKININ A; NOLPITANTIUM; SAREDUTANT; TETRODOTOXIN; VIMENTIN;

ANIMAL TISSUE; ARTICLE; BLADDER CONTRACTION; BLADDER MUCOSA; DETRUSOR MUSCLE; FEMALE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; CARBACHOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; IMMUNOHISTOCHEMISTRY; MUCOUS MEMBRANE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NEUROKININ A; NEUROTRANSMITTER AGENTS; RECEPTORS, NEUROKININ-2; SWINE; URINARY BLADDER; UROTHELIUM;

EID: 41649111894     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.29     Document Type: Article

References (30)

1. Arunlakshana O, Schild HO (1959). Some quantitative uses of drug antagonists. Br J Pharmacol 14: 48-58.
2. Birder LA, Apodaca G, De Groat WC, Kanai AJ (1998). Adrenergic-and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder. Am J Physiol 275: F226-F229.
3. Birder LA, Kanai AJ, de Groat WC, Kiss S, Nealen ML, Burke NE et al. (2001). Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells. Proc Natl Acad Sci USA 98: 13396-13401.
4. Burcher E, Zeng XP, Strigas J, Shang F, Millard RJ, Moore KH (2000). Autoradiographic localization of tachykinin and calcitonin generelated peptide receptors in adult urinary bladder. J Urol 163: 331-337.
5. Candenas L, Lecci A, Pinto FM, Patak E, Maggi CA, Pennefather JN (2005). Tachykinins and tachykinin receptors: effects in the genitourinary tract. Life Sci 76: 835-862.
6. Crowe R, Burnstock G (1989). A histochemical and immunohistochemical study of the autonomic innervation of the lower urinary tract of the female pig. Is the pig a good model for the human bladder and urethra? J Urol 141: 414-422.
7. Drake MJ, Fry CH, Eyden B (2006). Structural characterization of myofibroblasts in the bladder. BJU Int 97: 29-32.
8. Ferguson DR, Kennedy I, Burton TJ (1997). ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - a possible sensory mechanism? J Physiol 505: 503-511.
9. Fry CH, Ikeda Y, Harvey R, Wu C, Sui GP (2004). Control of bladder function by peripheral nerves: avenues for novel drug targets. Urology 63 (Suppl 1): 24-31; review.
10. Gillespie JI, Markerink-van Ittersum M, De Vente J (2006). Endogenous nitric oxide/cGMP signalling in the guinea pig bladder: evidence for distinct populations of sub-urothelial interstitial cells. Cell Tissue Res 325: 325-332.
11. Hawthorn MH, Chapple CR, Cock M, Chess-Williams R (2000). Urothelium-derived inhibitory factor(s) influences on detrusor muscle contractility in vitro. Br J Pharmacol 129: 416-419.
12. Hinz B (2006). Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission. Eur J Cell Biol 85: 175-181.
13. Kumar V, Chapple CC, Chess-Williams R (2004). Characteristics of adenosine triphosphate release from porcine and human normal bladder. J Urol 172: 744-747.
14. Lecci A, Maggi CA (2001). Tachykinins as modulators of the micturition reflex in the central and peripheral nervous system. Regul Pept 101: 1-18. Review.
15. Lecci A, Maggi CA (2003). Peripheral tachykinin receptors as potential therapeutic targets in visceral diseases. Expert Opin Ther Targets 7: 343-362. Review.
16. Mantyh CR, Gates TS, Zimmerman RP, Welton ML, Passaro Jr EP, Vigna SR et al. (1988). Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease. Proc Natl Acad Sci USA 85: 3235-3239.
17. Menzies JR, McKee R, Corbett AD (2001). Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation. Regul Pept 99: 151-156.
18. Mukerji G, Yiangou Y, Grogono J, Underwood J, Agarwal SK, Khullar V et al. (2006). Localization of M2 and M3 muscarinic receptors in human bladder disorders and their clinical correlations. J Urol 176: 367-373.
19. Mussap CJ, Stamatakos C, Burcher E (1996). Radioligand binding, autoradiographic and functional studies demonstrate tachykinin NK-2 receptors in dog urinary bladder. J Pharmacol Exp Ther 279: 423-434.
20. Pennefather JN, Lecci A, Candenas ML, Patak E, Pinto FM, Maggi CA (2004). Tachykinins and tachykinin receptors: a growing family. Life Sci 74: 1445-1463. Review.
21. Renzi D, Pellegrini B, Tonelli F, Surrenti C, Calabro A (2000). Substance P (neurokinin-1) and neurokinin A (neurokinin-2) receptor gene and protein expression in the healthy and inflamed human intestine. Am J Pathol 157: 1511-1522.
22. Sibley GNA (1984). A comparison of spontaneous and nerve mediated activity in bladder muscle from man, pig and rabbit. J Physiol 354: 431-443.
23. Sjogren C, Andersson KE, Husted S (1982). Contractile effects of some polypeptides on the isolated urinary bladder of guinea-pig, rabbit, and rat. Acta Pharmacol Toxicol 50: 175-184.
24. Smet PJ, Moore KH, Jonavicius J (1997). Distribution and colocalization of calcitonin gene-related peptide, tachykinins, and vaso-active intestinal peptide in normal and idiopathic unstable human urinary bladder. Lab Invest 77: 37-49.
25. Templeman L, Sellers DJ, Chapple CR, Rosario DJ, Hay DP, Chess-Williams R (2003). Investigation of neurokinin-2 and -3 receptors in the human and pig bladder. BJU Int 92: 787-792.
26. Wang P, Luthin GR, Ruggieri MR (1995). Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. J Pharmacol Exp Ther 273: 959-966.
27. Warner FW, Shang F, Millard RJ, Burcher E (2002). Enhancement of neurokinin A-induced smooth muscle contraction in human urinary bladder by mucosal removal and phosphoramidon: relationship to peptidase inhibition. Eur J Pharmacol 438: 171-177.
28. Wiseman OJ, Fowler CJ, Landon DN (2003). The role of the human bladder lamina propria myofibroblast. BJU Int 91: 89-93.
29. Yoshida M, Inadome A, Maeda Y, Satoji Y, Masunaga K, Sugiyama Y et al. (2006). Non-neuronal cholinergic system in human bladder urothelium. Urology 67: 425-430.
30. 2 receptors in human urinary bladder. J Urol 153: 1688-1692.