Oxidative stress and α 1-adrenoceptor-mediated stimulation of the Cl -/HCO 3 - exchanger in immortalized SHR proximal tubular epithelial cells

British Journal of Pharmacology

Volumn 153, Issue 7, 2008, Pages 1445-1455

  Simao S ^a   Fraga, S ^a   Jose, P A ^b   Soares Da Silva, P ^a,c  

^a University of Porto   (Portugal)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Institute of Pharmacology and Therapeutics   (Portugal)

Author keywords

1 adrenoceptor; Cl HCO 3 exchanger; H 2O 2; Hypertension; SHR; WKY

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; APOCYNIN; BICARBONATE CHLORIDE ANTIPORTER; CHELERYTHRINE; HYDROGEN PEROXIDE; NORADRENALIN; PHENYLEPHRINE; PRAZOSIN; YOHIMBINE; ADRENERGIC RECEPTOR ALPHA(1A); ADRENERGIC RECEPTOR ALPHA(1B);

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; EPITHELIUM CELL; HYPERTENSION; KIDNEY PROXIMAL TUBULE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; GENE EXPRESSION; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ANIMALS; CELLS, CULTURED; CHLORIDE-BICARBONATE ANTIPORTERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GENE EXPRESSION; HYDROGEN PEROXIDE; HYPERTENSION; KIDNEY TUBULES, PROXIMAL; NOREPINEPHRINE; OXIDATIVE STRESS; PHENYLEPHRINE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, ADRENERGIC, ALPHA-1; SIGNAL TRANSDUCTION;

EID: 41649106068     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.16     Document Type: Article

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