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Volumn 146, Issue 2, 2008, Pages 202-210

Lowering Homocysteine Decreases Levels and Expression of VEGF165 and Endostatin

Author keywords

angiogenesis; diabetes mellitus; endostatin; homocysteine; peripheral arterial disease; vascular endothelial growth factor

Indexed keywords

CYANOCOBALAMIN; ENDOSTATIN; FOLIC ACID; HOMOCYSTEINE; PYRIDOXINE; THIAMINE; TRI B; UNCLASSIFIED DRUG; VASCULOTROPIN 165;

EID: 41649101413     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2007.04.038     Document Type: Article
Times cited : (12)

References (74)
  • 1
    • 16344389190 scopus 로고    scopus 로고
    • Angiogenesis. Where do we stand now?
    • Simmons M. Angiogenesis. Where do we stand now?. Circulation 111 (2005) 1556
    • (2005) Circulation , vol.111 , pp. 1556
    • Simmons, M.1
  • 2
    • 2642565248 scopus 로고    scopus 로고
    • Therapeutic angiogenesis and vasculogenesis for ischemic disease part I: Angiogenic cytokines
    • Losordo D.W., and Dimmeler S. Therapeutic angiogenesis and vasculogenesis for ischemic disease part I: Angiogenic cytokines. Circulation 109 (2004) 2487
    • (2004) Circulation , vol.109 , pp. 2487
    • Losordo, D.W.1    Dimmeler, S.2
  • 3
    • 0037377376 scopus 로고    scopus 로고
    • Angiogenesis: Basic pathophysiology and implications for disease
    • Felmeden D.C., Blann A.D., and Lip G.Y.H. Angiogenesis: Basic pathophysiology and implications for disease. Eur Heart J 24 (2003) 586
    • (2003) Eur Heart J , vol.24 , pp. 586
    • Felmeden, D.C.1    Blann, A.D.2    Lip, G.Y.H.3
  • 4
    • 2442522478 scopus 로고    scopus 로고
    • Serum levels of endostatin, vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in patients with acute myocardial infarction undergoing early reperfusion therapy
    • Seko Y., Fukuda S., and Nagai R. Serum levels of endostatin, vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in patients with acute myocardial infarction undergoing early reperfusion therapy. Clin Sci (Lond) 106 (2004) 439
    • (2004) Clin Sci (Lond) , vol.106 , pp. 439
    • Seko, Y.1    Fukuda, S.2    Nagai, R.3
  • 5
    • 0032947422 scopus 로고    scopus 로고
    • Prospective blinded study of the relationship between plasma homocysteine and progression of symptomatic peripheral arterial disease
    • Taylor L.M., Moneta G.L., Sexton G.J., et al. Prospective blinded study of the relationship between plasma homocysteine and progression of symptomatic peripheral arterial disease. J Vasc Surg 29 (1999) 8
    • (1999) J Vasc Surg , vol.29 , pp. 8
    • Taylor, L.M.1    Moneta, G.L.2    Sexton, G.J.3
  • 6
    • 0037986773 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and vascular disease-a role for DNA hypomethylation?
    • van Guldener C., and Stehouwer C.D.A. Hyperhomocysteinemia and vascular disease-a role for DNA hypomethylation?. Lancet 361 (2003) 1668
    • (2003) Lancet , vol.361 , pp. 1668
    • van Guldener, C.1    Stehouwer, C.D.A.2
  • 8
    • 0037164104 scopus 로고    scopus 로고
    • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis
    • The homocysteine studies collaboration
    • The homocysteine studies collaboration. Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis. JAMA 288 (2002) 2015
    • (2002) JAMA , vol.288 , pp. 2015
  • 9
    • 0033533435 scopus 로고    scopus 로고
    • Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: The Framingham Study
    • Bostom A.G., Rosenberg I.H., Silbershatz H., et al. Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: The Framingham Study. Ann Intern Med 131 (1999) 352
    • (1999) Ann Intern Med , vol.131 , pp. 352
    • Bostom, A.G.1    Rosenberg, I.H.2    Silbershatz, H.3
  • 10
    • 0033547813 scopus 로고    scopus 로고
    • Homocyst(e)ine, diet, and cardiovascular diseases: A statement for healthcare professionals from the nutrition committee, American Heart Association
    • Malinow M.R., Bostom A.G., and Krauss R.M. Homocyst(e)ine, diet, and cardiovascular diseases: A statement for healthcare professionals from the nutrition committee, American Heart Association. Circulation 99 (1999) 178
    • (1999) Circulation , vol.99 , pp. 178
    • Malinow, M.R.1    Bostom, A.G.2    Krauss, R.M.3
  • 11
    • 0035920267 scopus 로고    scopus 로고
    • Investigation of relationship between reduced, oxidized, and protein-bound homocysteine and vascular endothelial function in healthy human subjects
    • Chambers J.C., Ueland P.M., Wright M., et al. Investigation of relationship between reduced, oxidized, and protein-bound homocysteine and vascular endothelial function in healthy human subjects. Circ Res 89 (2001) 187
    • (2001) Circ Res , vol.89 , pp. 187
    • Chambers, J.C.1    Ueland, P.M.2    Wright, M.3
  • 12
    • 0033374591 scopus 로고    scopus 로고
    • Physiological increments in plasma homocysteine induce vascular endothelial dysfunction in normal human subjects
    • Chambers J.C., Obeid O.A., and Kooner J.S. Physiological increments in plasma homocysteine induce vascular endothelial dysfunction in normal human subjects. Arterioscler Thromb Vasc Biol 19 (1999) 2922
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2922
    • Chambers, J.C.1    Obeid, O.A.2    Kooner, J.S.3
  • 13
    • 0032480790 scopus 로고    scopus 로고
    • Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults
    • Bellamy M.F., McDowell I.F.W., Ramsey M.W., et al. Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults. Circulation 98 (1998) 1848
    • (1998) Circulation , vol.98 , pp. 1848
    • Bellamy, M.F.1    McDowell, I.F.W.2    Ramsey, M.W.3
  • 14
    • 0032783131 scopus 로고    scopus 로고
    • Oral folate enhances endothelial function in hyperhomocysteinaemic subjects
    • Bellamy M.F., McDowell I.F., Ramsey M.W., et al. Oral folate enhances endothelial function in hyperhomocysteinaemic subjects. Eur J Clin Invest 29 (1999) 659
    • (1999) Eur J Clin Invest , vol.29 , pp. 659
    • Bellamy, M.F.1    McDowell, I.F.2    Ramsey, M.W.3
  • 15
    • 0034649324 scopus 로고    scopus 로고
    • Improved Vascular Endothelial Function After Oral B Vitamins An Effect Mediated Through Reduced Concentrations of Free Plasma Homocysteine
    • Chambers J.C., Ueland P.M., Obeid O.A., Wrigley J., Refsum H., and Kooner J.S. Improved Vascular Endothelial Function After Oral B Vitamins An Effect Mediated Through Reduced Concentrations of Free Plasma Homocysteine. Circulation 102 (2000) 2479
    • (2000) Circulation , vol.102 , pp. 2479
    • Chambers, J.C.1    Ueland, P.M.2    Obeid, O.A.3    Wrigley, J.4    Refsum, H.5    Kooner, J.S.6
  • 16
    • 0033405725 scopus 로고    scopus 로고
    • Folic acid improves arterial endothelial function in adults with hyperhomocystinemia
    • Woo K.S., Chook P., Lolin Y.I., et al. Folic acid improves arterial endothelial function in adults with hyperhomocystinemia. J Am Coll Cardiol 34 (1999) 2002
    • (1999) J Am Coll Cardiol , vol.34 , pp. 2002
    • Woo, K.S.1    Chook, P.2    Lolin, Y.I.3
  • 17
    • 0033664588 scopus 로고    scopus 로고
    • Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia
    • Duan J., Murohara T., Ikeda H., et al. Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia. Arterioscler Thromb Vasc Biol 20 (2000) 2579
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2579
    • Duan, J.1    Murohara, T.2    Ikeda, H.3
  • 18
    • 0037394602 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and tissue factor in patients with established peripheral artery disease: A link between angiogenesis and thrombogenesis?
    • Makin A.J., Chung N.A.Y., Silverman S.H., et al. Vascular endothelial growth factor and tissue factor in patients with established peripheral artery disease: A link between angiogenesis and thrombogenesis?. Clin Sci 104 (2003) 397
    • (2003) Clin Sci , vol.104 , pp. 397
    • Makin, A.J.1    Chung, N.A.Y.2    Silverman, S.H.3
  • 19
    • 2442572249 scopus 로고    scopus 로고
    • Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4
    • Roybal C.N., Yang S., Sun C.W., et al. Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4. J Biol Chem 279 (2004) 14844
    • (2004) J Biol Chem , vol.279 , pp. 14844
    • Roybal, C.N.1    Yang, S.2    Sun, C.W.3
  • 20
    • 0036340187 scopus 로고    scopus 로고
    • Regulation of angiogenesis in diabetic retinopathy: Possible balance between vascular endothelial growth factor and endostatin
    • Noma H., Funatsu H., Yamashita H., et al. Regulation of angiogenesis in diabetic retinopathy: Possible balance between vascular endothelial growth factor and endostatin. Arch Ophthalmol 120 (2002) 1075
    • (2002) Arch Ophthalmol , vol.120 , pp. 1075
    • Noma, H.1    Funatsu, H.2    Yamashita, H.3
  • 21
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N., and Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 18 (1997) 4
    • (1997) Endocr Rev , vol.18 , pp. 4
    • Ferrara, N.1    Davis-Smyth, T.2
  • 22
    • 1842366022 scopus 로고    scopus 로고
    • Intracellular pool of vascular endothelial growth factor in human neutrophils
    • Gaudry M., Bregerie O., Andrieu V., et al. Intracellular pool of vascular endothelial growth factor in human neutrophils. Blood 90 (1997) 4153
    • (1997) Blood , vol.90 , pp. 4153
    • Gaudry, M.1    Bregerie, O.2    Andrieu, V.3
  • 23
    • 25444522479 scopus 로고    scopus 로고
    • Role of angiogenesis in cardiovascular disease: A critical appraisal
    • Khurana R., Simons M., Martin J.F., et al. Role of angiogenesis in cardiovascular disease: A critical appraisal. Circulation 112 (2005) 1813
    • (2005) Circulation , vol.112 , pp. 1813
    • Khurana, R.1    Simons, M.2    Martin, J.F.3
  • 24
    • 0037288588 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases the migration and proliferation of smooth muscle cells through the mediation of growth factors released by endothelial cells
    • Cucina A., Borrelli V., Randone B., et al. Vascular endothelial growth factor increases the migration and proliferation of smooth muscle cells through the mediation of growth factors released by endothelial cells. J Surg Res 109 (2003) 16
    • (2003) J Surg Res , vol.109 , pp. 16
    • Cucina, A.1    Borrelli, V.2    Randone, B.3
  • 25
    • 0032542072 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: Possible pathophysiological significance of VEGF in progression of atherosclerosis
    • Inoue M., Itoh H., Ueda M., et al. Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: Possible pathophysiological significance of VEGF in progression of atherosclerosis. Circulation 98 (1998) 2108
    • (1998) Circulation , vol.98 , pp. 2108
    • Inoue, M.1    Itoh, H.2    Ueda, M.3
  • 26
    • 0041592491 scopus 로고    scopus 로고
    • Serum concentrations of vascular endothelial growth factor and monocyte-colony stimulating factor in peripheral arterial disease
    • Matsui K., Yoshioka T., Murakami Y., et al. Serum concentrations of vascular endothelial growth factor and monocyte-colony stimulating factor in peripheral arterial disease. Circ J 67 (2003) 660
    • (2003) Circ J , vol.67 , pp. 660
    • Matsui, K.1    Yoshioka, T.2    Murakami, Y.3
  • 27
    • 0035125741 scopus 로고    scopus 로고
    • Oxidative stress and increase of vascular endothelial growth factor in plasma of patients with peripheral arterial occlusive disease
    • Roller R.E., Renner W., Dorr A., et al. Oxidative stress and increase of vascular endothelial growth factor in plasma of patients with peripheral arterial occlusive disease. Thromb Haemostasis 85 (2001) 368
    • (2001) Thromb Haemostasis , vol.85 , pp. 368
    • Roller, R.E.1    Renner, W.2    Dorr, A.3
  • 28
    • 2542560424 scopus 로고    scopus 로고
    • Plasma vascular endothelial growth factor level is elevated in patients with multivessel coronary artery disease
    • Nakajima K., Tabata S., Yamashita T., et al. Plasma vascular endothelial growth factor level is elevated in patients with multivessel coronary artery disease. Clin Cardiol 27 (2004) 281
    • (2004) Clin Cardiol , vol.27 , pp. 281
    • Nakajima, K.1    Tabata, S.2    Yamashita, T.3
  • 29
    • 17044384530 scopus 로고    scopus 로고
    • Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: Relationship to VEGF, glycemic control, endothelial damage/dysfunction and atherosclerosis
    • Lim H.S., Lip G.Y., and Blann A.D. Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: Relationship to VEGF, glycemic control, endothelial damage/dysfunction and atherosclerosis. Atherosclerosis 180 (2005) 113
    • (2005) Atherosclerosis , vol.180 , pp. 113
    • Lim, H.S.1    Lip, G.Y.2    Blann, A.D.3
  • 30
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: Endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly M.S., Boehm T., Shing Y., et al. Endostatin: Endogenous inhibitor of angiogenesis and tumor growth. Cell 88 (1997) 277
    • (1997) Cell , vol.88 , pp. 277
    • O'Reilly, M.S.1    Boehm, T.2    Shing, Y.3
  • 31
    • 0033528660 scopus 로고    scopus 로고
    • Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice
    • Moulton K.S., Heller E., Konerding M.A., et al. Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation 99 (1999) 1726
    • (1999) Circulation , vol.99 , pp. 1726
    • Moulton, K.S.1    Heller, E.2    Konerding, M.A.3
  • 32
    • 18144404148 scopus 로고    scopus 로고
    • Physiological role of collagen XVIII and endostatin
    • Marneros A.G., and Olsen B.R. Physiological role of collagen XVIII and endostatin. FASEB J 19 (2005) 716
    • (2005) FASEB J , vol.19 , pp. 716
    • Marneros, A.G.1    Olsen, B.R.2
  • 33
    • 0034672644 scopus 로고    scopus 로고
    • Generation and degradation of human endostatin proteins by various proteinases
    • Ferreras M., Felbor U., Lenhard T., et al. Generation and degradation of human endostatin proteins by various proteinases. FEBS Lett 486 (2000) 247
    • (2000) FEBS Lett , vol.486 , pp. 247
    • Ferreras, M.1    Felbor, U.2    Lenhard, T.3
  • 34
    • 0034210660 scopus 로고    scopus 로고
    • Endostatin induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis
    • Dixelius J., Larsson H., Sasaki T., et al. Endostatin induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis. Blood 95 (2000) 3403
    • (2000) Blood , vol.95 , pp. 3403
    • Dixelius, J.1    Larsson, H.2    Sasaki, T.3
  • 35
    • 0033575658 scopus 로고    scopus 로고
    • Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding
    • Yamaguchi N., Anand-Apte B., Lee M., et al. Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J 18 (1999) 4414
    • (1999) EMBO J , vol.18 , pp. 4414
    • Yamaguchi, N.1    Anand-Apte, B.2    Lee, M.3
  • 36
    • 0033647409 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in Type 2 Diabetes. Relationship to macroangiopathy, nephropathy, and insulin resistance
    • Buysschaert M., Dramais A.-S., Wallemacq P.E., et al. Hyperhomocysteinemia in Type 2 Diabetes. Relationship to macroangiopathy, nephropathy, and insulin resistance. Diabetes Care 23 (2000) 1816
    • (2000) Diabetes Care , vol.23 , pp. 1816
    • Buysschaert, M.1    Dramais, A.-S.2    Wallemacq, P.E.3
  • 37
    • 0037132839 scopus 로고    scopus 로고
    • Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease
    • Quinlivan E.P., McPartlin J., McNulty H., et al. Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet 359 (2002) 227
    • (2002) Lancet , vol.359 , pp. 227
    • Quinlivan, E.P.1    McPartlin, J.2    McNulty, H.3
  • 38
    • 0035060498 scopus 로고    scopus 로고
    • Pitfalls in the measurement of circulating vascular endothelial growth factor
    • Jelkmann W. Pitfalls in the measurement of circulating vascular endothelial growth factor. Clin Chem 47 (2001) 617
    • (2001) Clin Chem , vol.47 , pp. 617
    • Jelkmann, W.1
  • 39
    • 0037334780 scopus 로고    scopus 로고
    • Outcome of vitreous surgery and the balance between vascular endothelial growth factor and endostatin
    • Funatsu H., Yamashita H., Noma H., et al. Outcome of vitreous surgery and the balance between vascular endothelial growth factor and endostatin. Invest Ophthalmol Vis Sci 44 (2003) 1042
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 1042
    • Funatsu, H.1    Yamashita, H.2    Noma, H.3
  • 40
    • 0034794547 scopus 로고    scopus 로고
    • A prospective analysis of plasma endostatin levels in colorectal cancer patients with liver metastases
    • Feldman A.L., Alexander Jr. H.R., Bartlett D.L., et al. A prospective analysis of plasma endostatin levels in colorectal cancer patients with liver metastases. Ann Surg Oncol 8 (2001) 741
    • (2001) Ann Surg Oncol , vol.8 , pp. 741
    • Feldman, A.L.1    Alexander Jr., H.R.2    Bartlett, D.L.3
  • 41
    • 0034488630 scopus 로고    scopus 로고
    • Serum endostatin levels are elevated and correlate with serum vascular endothelial growth factor levels in patients with stage IV clear cell renal cancer
    • Feldman A.L., Tamarkin L., Paciotti G.F., et al. Serum endostatin levels are elevated and correlate with serum vascular endothelial growth factor levels in patients with stage IV clear cell renal cancer. Clin Cancer Res 6 (2000) 4628
    • (2000) Clin Cancer Res , vol.6 , pp. 4628
    • Feldman, A.L.1    Tamarkin, L.2    Paciotti, G.F.3
  • 42
    • 0033851818 scopus 로고    scopus 로고
    • Lack of hypoxic stimulation of VEGF secretion from neutrophils and platelets
    • Koehne P., Willam C., Strauss E., et al. Lack of hypoxic stimulation of VEGF secretion from neutrophils and platelets. Am J Physiol Heart Circ Physiol 279 (2000) H817
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Koehne, P.1    Willam, C.2    Strauss, E.3
  • 43
    • 0034891805 scopus 로고    scopus 로고
    • Expression of the endostatin gene in epithelial ovarian cancer
    • Kohkichi H., Ritsuto F., and Kohji M. Expression of the endostatin gene in epithelial ovarian cancer. Clin Cancer Res 7 (2001) 2405
    • (2001) Clin Cancer Res , vol.7 , pp. 2405
    • Kohkichi, H.1    Ritsuto, F.2    Kohji, M.3
  • 44
    • 0026036480 scopus 로고
    • The association of elevated plasma homocyst(e)ine with progression of symptomatic peripheral arterial disease
    • Taylor L.M., DeFrang R.D., Harris E.J., et al. The association of elevated plasma homocyst(e)ine with progression of symptomatic peripheral arterial disease. J Vasc Surg 13 (1991) 128
    • (1991) J Vasc Surg , vol.13 , pp. 128
    • Taylor, L.M.1    DeFrang, R.D.2    Harris, E.J.3
  • 45
    • 0042334457 scopus 로고    scopus 로고
    • Are elevated homocysteine plasma levels related to peripheral arterial disease?. Results from a cross-sectional study of 6880 primary care patients
    • Darius H., Pittrow D., Haberl R., et al. Are elevated homocysteine plasma levels related to peripheral arterial disease?. Results from a cross-sectional study of 6880 primary care patients. Eur J Clin Invest 33 (2003) 751
    • (2003) Eur J Clin Invest , vol.33 , pp. 751
    • Darius, H.1    Pittrow, D.2    Haberl, R.3
  • 46
    • 0024391453 scopus 로고
    • Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease
    • Malinow M.R., Kang S.S., Taylor L.M., et al. Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease. Circulation 79 (1989) 1180
    • (1989) Circulation , vol.79 , pp. 1180
    • Malinow, M.R.1    Kang, S.S.2    Taylor, L.M.3
  • 47
    • 0034941056 scopus 로고    scopus 로고
    • Homocysteine-an innocent bystander in vascular disease?
    • Chambers J.C., and Kooners J.S. Homocysteine-an innocent bystander in vascular disease?. Eur Heart J 22 (2001) 717
    • (2001) Eur Heart J , vol.22 , pp. 717
    • Chambers, J.C.1    Kooners, J.S.2
  • 48
    • 1542440251 scopus 로고    scopus 로고
    • Homocysteine levels are associated with the severity of peripheral arterial disease in type 2 diabetic patients
    • Ciccarone E., Di Castelnuovo A., Assanelli D., et al. Homocysteine levels are associated with the severity of peripheral arterial disease in type 2 diabetic patients. J Thromb Haemost 1 (2003) 2540
    • (2003) J Thromb Haemost , vol.1 , pp. 2540
    • Ciccarone, E.1    Di Castelnuovo, A.2    Assanelli, D.3
  • 49
    • 33644674567 scopus 로고    scopus 로고
    • Homocysteine and other biochemical parameters in type 2 diabetes mellitus with different diabetic duration or diabetic retinopathy
    • Huang E.J., Kuo W.W., Chen Y.J., et al. Homocysteine and other biochemical parameters in type 2 diabetes mellitus with different diabetic duration or diabetic retinopathy. Clin Chim Acta 366 (2006) 293
    • (2006) Clin Chim Acta , vol.366 , pp. 293
    • Huang, E.J.1    Kuo, W.W.2    Chen, Y.J.3
  • 50
    • 0035940411 scopus 로고    scopus 로고
    • Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction
    • Weiss N., Zhang Y.-Y., Heydrick S., et al. Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction. Proc Natl Acad Sci USA 98 (2001) 12503
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12503
    • Weiss, N.1    Zhang, Y.-Y.2    Heydrick, S.3
  • 51
    • 0031018333 scopus 로고    scopus 로고
    • Hyperhomocyst(e) inemia is associated with impaired endothelium-dependent vasodilation in humans
    • Tawakol A., Omland T., Gerhard M., et al. Hyperhomocyst(e) inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation 95 (1997) 1119
    • (1997) Circulation , vol.95 , pp. 1119
    • Tawakol, A.1    Omland, T.2    Gerhard, M.3
  • 52
    • 0030188563 scopus 로고    scopus 로고
    • The oxidant stress of hyperhomocyst(e)inemia
    • Loscalzo J. The oxidant stress of hyperhomocyst(e)inemia. J Clin Invest 98 (1996) 5
    • (1996) J Clin Invest , vol.98 , pp. 5
    • Loscalzo, J.1
  • 53
    • 0347951237 scopus 로고    scopus 로고
    • Hyperhomocysteinemia activates nuclear factor-κB in endothelial cells via oxidative stress
    • Au-Yeung K.K., Woo C.W., Sung F.L., et al. Hyperhomocysteinemia activates nuclear factor-κB in endothelial cells via oxidative stress. Circ Res 94 (2004) 28
    • (2004) Circ Res , vol.94 , pp. 28
    • Au-Yeung, K.K.1    Woo, C.W.2    Sung, F.L.3
  • 54
    • 0035929641 scopus 로고    scopus 로고
    • Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response
    • Zhang C., Cai Y., Adachi M.T., et al. Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response. J Biol Chem 276 (2001) 35867
    • (2001) J Biol Chem , vol.276 , pp. 35867
    • Zhang, C.1    Cai, Y.2    Adachi, M.T.3
  • 55
    • 0041989674 scopus 로고    scopus 로고
    • TDAG51 Is induced by homocysteine, promotes detachmentmediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia
    • Hossain G.S., van Thienen J.V., Werstuck G.H., et al. TDAG51 Is induced by homocysteine, promotes detachmentmediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia. J Biol Chem 278 (2003) 30317
    • (2003) J Biol Chem , vol.278 , pp. 30317
    • Hossain, G.S.1    van Thienen, J.V.2    Werstuck, G.H.3
  • 56
    • 20044391979 scopus 로고    scopus 로고
    • Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine
    • Lee S.J., Kim K.M., Namkoong S., et al. Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine. J Biol Chem 280 (2005) 5781
    • (2005) J Biol Chem , vol.280 , pp. 5781
    • Lee, S.J.1    Kim, K.M.2    Namkoong, S.3
  • 57
    • 0042733751 scopus 로고    scopus 로고
    • Homocysteine induces vascular endothelial growth factor expression in differentiated THP-1 macrophages
    • Maeda M., Yamamoto I., Fujio Y., et al. Homocysteine induces vascular endothelial growth factor expression in differentiated THP-1 macrophages. Biochim Biophys Acta 1623 (2003) 41
    • (2003) Biochim Biophys Acta , vol.1623 , pp. 41
    • Maeda, M.1    Yamamoto, I.2    Fujio, Y.3
  • 58
    • 18044400553 scopus 로고    scopus 로고
    • Effect of folic acid treatment on endothelium-dependent vasodilatation and nitric oxide-derived end products in hyperhomocysteinemic subjects
    • Holven K.B., Holm T., Aukrust P., et al. Effect of folic acid treatment on endothelium-dependent vasodilatation and nitric oxide-derived end products in hyperhomocysteinemic subjects. Am J Med 110 (2001) 536
    • (2001) Am J Med , vol.110 , pp. 536
    • Holven, K.B.1    Holm, T.2    Aukrust, P.3
  • 59
    • 14744301954 scopus 로고    scopus 로고
    • Short-term oral acid folic supplementation enhances endothelial function in patients with type 2 diabetes
    • Mangoni A.A., Sherwood R.A., Asonganyi B., et al. Short-term oral acid folic supplementation enhances endothelial function in patients with type 2 diabetes. Am J Hypertens 18 (2005) 220
    • (2005) Am J Hypertens , vol.18 , pp. 220
    • Mangoni, A.A.1    Sherwood, R.A.2    Asonganyi, B.3
  • 60
    • 1942452435 scopus 로고    scopus 로고
    • Reduced pericardial levels of endostatin correlate with collateral development in patients with ischemic heart disease
    • Panchal V.R., Rehman J., Nguyen A.T., et al. Reduced pericardial levels of endostatin correlate with collateral development in patients with ischemic heart disease. J Am Coll Cardiol 43 (2004) 1383
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1383
    • Panchal, V.R.1    Rehman, J.2    Nguyen, A.T.3
  • 61
    • 0345389960 scopus 로고    scopus 로고
    • Fasting and post-methionine homocysteine levels in NIDDM determinants and correlations with retinopathy, albuminuria, and cardiovascular disease
    • Smulders Y.M., Rakic M., Slaats E.H., et al. Fasting and post-methionine homocysteine levels in NIDDM determinants and correlations with retinopathy, albuminuria, and cardiovascular disease. Diabetes Care 22 (1999) 125
    • (1999) Diabetes Care , vol.22 , pp. 125
    • Smulders, Y.M.1    Rakic, M.2    Slaats, E.H.3
  • 62
    • 0033852483 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in diabetic vascular complications
    • Aiello L.P., and Wong J.S. Role of vascular endothelial growth factor in diabetic vascular complications. Kidney Int Suppl 77 (2000) S113
    • (2000) Kidney Int Suppl , vol.77
    • Aiello, L.P.1    Wong, J.S.2
  • 63
    • 33747792741 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in ocular angiogenesis
    • Shams N., and Ianchulev T. Role of vascular endothelial growth factor in ocular angiogenesis. Ophthalmol Clin N Am 19 (2006) 335
    • (2006) Ophthalmol Clin N Am , vol.19 , pp. 335
    • Shams, N.1    Ianchulev, T.2
  • 64
    • 0037898378 scopus 로고    scopus 로고
    • Homocysteine as a risk factor for nephropathy and retinopathy in type 2 diabetes
    • Looker H.C., Fagot-Campagna A., Gunter E.W., et al. Homocysteine as a risk factor for nephropathy and retinopathy in type 2 diabetes. Diabetologia 46 (2003) 766
    • (2003) Diabetologia , vol.46 , pp. 766
    • Looker, H.C.1    Fagot-Campagna, A.2    Gunter, E.W.3
  • 65
    • 0036340187 scopus 로고    scopus 로고
    • Regulation of angiogenesis in diabetic retinopathy: Possible balance between vascular endothelial growth factor and endostatin
    • Noma H., Funatsu H., Yamashita H., et al. Regulation of angiogenesis in diabetic retinopathy: Possible balance between vascular endothelial growth factor and endostatin. Arch Ophthalmol 120 (2002) 1075
    • (2002) Arch Ophthalmol , vol.120 , pp. 1075
    • Noma, H.1    Funatsu, H.2    Yamashita, H.3
  • 66
    • 33645931644 scopus 로고    scopus 로고
    • Pericardial fluid and serum levels of vascular endothelial growth factor and endostatin in patients with or without coronary artery disease
    • Liou J.Y., Shyu K.G., Lu M.J., et al. Pericardial fluid and serum levels of vascular endothelial growth factor and endostatin in patients with or without coronary artery disease. J Formos Med Assoc 105 (2006) 377
    • (2006) J Formos Med Assoc , vol.105 , pp. 377
    • Liou, J.Y.1    Shyu, K.G.2    Lu, M.J.3
  • 67
    • 0033786484 scopus 로고    scopus 로고
    • Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis
    • Nagashima M., Asano G., and Yoshino S. Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis. J Rheumatol 27 (2000) 2339
    • (2000) J Rheumatol , vol.27 , pp. 2339
    • Nagashima, M.1    Asano, G.2    Yoshino, S.3
  • 68
    • 0141962585 scopus 로고    scopus 로고
    • Imbalance between vascular endothelial growth factor and endostatin in emphysema
    • Kanazawa H., Hirata K., and Yoshikawa J. Imbalance between vascular endothelial growth factor and endostatin in emphysema. Eur Respir J 22 (2003) 609
    • (2003) Eur Respir J , vol.22 , pp. 609
    • Kanazawa, H.1    Hirata, K.2    Yoshikawa, J.3
  • 69
    • 14744297361 scopus 로고    scopus 로고
    • Imbalance in the production between vascular endothelial growth factor and endostatin in Kawasaki disease
    • Takeshita S., Kawamura Y., Takabayashi H., et al. Imbalance in the production between vascular endothelial growth factor and endostatin in Kawasaki disease. Clin Exp Immunol 139 (2005) 575
    • (2005) Clin Exp Immunol , vol.139 , pp. 575
    • Takeshita, S.1    Kawamura, Y.2    Takabayashi, H.3
  • 70
    • 33749058959 scopus 로고    scopus 로고
    • Altered angiogenic balance in ulcerative colitis: A key to impaired healing?
    • Sandor Z., Deng X.M., Khomenko T., et al. Altered angiogenic balance in ulcerative colitis: A key to impaired healing?. Biochem Biophys Res Commun 350 (2006) 147
    • (2006) Biochem Biophys Res Commun , vol.350 , pp. 147
    • Sandor, Z.1    Deng, X.M.2    Khomenko, T.3
  • 71
    • 33644543821 scopus 로고    scopus 로고
    • Serum endostatin levels are elevated and correlate with serum vascular endothelial growth factor levels in patients with pituitary adenomas
    • Gruszka A., Kunert-Radek J., Pawlikowski M., et al. Serum endostatin levels are elevated and correlate with serum vascular endothelial growth factor levels in patients with pituitary adenomas. Pituitary 8 (2005) 163
    • (2005) Pituitary , vol.8 , pp. 163
    • Gruszka, A.1    Kunert-Radek, J.2    Pawlikowski, M.3
  • 72
    • 1642482608 scopus 로고    scopus 로고
    • Correlation between serum vascular endothelial growth factor and endostatin levels in patients with breast cancer
    • Zhao J., Yan F., Ju H., et al. Correlation between serum vascular endothelial growth factor and endostatin levels in patients with breast cancer. Cancer Lett 204 (2004) 87
    • (2004) Cancer Lett , vol.204 , pp. 87
    • Zhao, J.1    Yan, F.2    Ju, H.3
  • 73
    • 19944415267 scopus 로고    scopus 로고
    • Altered expression of vascular endothelial growth factor, fibroblast growth factor-2 and endostatin in patients with hepatocellular carcinoma
    • Uematsu S., Higashi T., Nouso K., et al. Altered expression of vascular endothelial growth factor, fibroblast growth factor-2 and endostatin in patients with hepatocellular carcinoma. J Gastroenterol Hepatol 20 (2005) 583
    • (2005) J Gastroenterol Hepatol , vol.20 , pp. 583
    • Uematsu, S.1    Higashi, T.2    Nouso, K.3
  • 74
    • 0037351271 scopus 로고    scopus 로고
    • Serum levels of vascular endothelial growth factor, basic fibroblast growth factor and endostatin in human metastatic liver tumors
    • Miyashita M., Tajiri T., Yanagi K., et al. Serum levels of vascular endothelial growth factor, basic fibroblast growth factor and endostatin in human metastatic liver tumors. Hepatogastroenterology 50 (2003) 308
    • (2003) Hepatogastroenterology , vol.50 , pp. 308
    • Miyashita, M.1    Tajiri, T.2    Yanagi, K.3


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