Corrigendum to "Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury" [J Hepatol 49 (2008) 88-98] (DOI:10.1016/j.jhep.2008.01.032);Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury

Journal of Hepatology

Volumn 49, Issue 1, 2008, Pages 88-98

  Douglass, Angela ^a,b   Wallace, Karen ^a   Parr, Rebecca ^c   Park, Jennifer ^c   Durward, Elaine ^b   Broadbent, Ian ^b,c   Barelle, Caroline ^c   Porter, Andrew J ^b,d   Wright, Matthew C ^a,b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c PFIZER INC   (United States)

^d Haptogen Ltd   (United Kingdom)

Author keywords

C1 3; Drug targeting; Fibrosis; Gliotoxin; Liver; MMP 13; Myofibroblast; scAb; Stellate

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIBODY CONJUGATE; C1-3 ANTIBODY; C1-3 ANTIBODY FLUORESCEIN ISOTHIOCYANATE CONJUGATE; C1-3 ANTIBODY GLIOTOXIN CONJUGATE; CSBD9 ANTIBODY; CSBD9 ANTIBODY GLIOTOXIN CONJUGATE; FLUORESCEIN ISOTHIOCYANATE; GLIOTOXIN; RECOMBINANT ANTIBODY; STROMELYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE SEVERITY; DRUG ACTIVITY; DRUG BINDING; DRUG EFFECT; DRUG EFFICACY; DRUG HALF LIFE; DRUG TARGETING; ENZYME BLOOD LEVEL; IN VIVO STUDY; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; MACROPHAGE; MALE; MONOCYTE; MONOTHERAPY; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SCAR; STELLATE CELL;

EID: 41649096578     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.01.022     Document Type: Erratum

References (37)

1. Henderson N.C., and Iredale J.P. Liver fibrosis: cellular mechanisms of progression and resolution. Clin Sci (Lond) 112 (2007) 265-280
2. Wright M.C., Issa R., Smart D.E., Trim N., Murray G.I., Primrose J.N., et al. Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. Gastroenterology 121 (2001) 685-698
3. Oakley F., Meso M., Iredale J.P., Green K., Marek C.J., Zhou X., et al. Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. Gastroenterology 128 (2005) 108-120
4. Dekel R., Zvibel I., Brill S., Brazovsky E., Halpern Z., and Oren R. Gliotoxin ameliorates development of fibrosis and cirrhosis in a thioacetamide rat model. Dig Dis Sci 48 (2003) 1642-1647
5. Planaguma A., Claria J., Miquel R., Lopez-Parra M., Titos E., Masferrer J.L., et al. The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation. FASEB J 19 (2005) 1120-1122
6. Purohit V., and Brenner D.A. Mechanisms of alcohol-induced hepatic fibrosis: a summary of the Ron Thurman Symposium. Hepatology 43 (2006) 872-878
7. Radaeva S., Sun R., Jaruga B., Nguyen V.T., Tian Z., and Gao B. Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners. Gastroenterology 130 (2006) 435-452
8. Anan A., Baskin-Bey E.S., Bronk S.F., Werneburg N.W., Shah V.H., and Gores G.J. Proteasome inhibition induces hepatic stellate cell apoptosis. Hepatology 43 (2006) 335-344
9. Streetz K.L., Tacke F., Leifeld L., Wustefeld T., Graw A., Klein C., et al. Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases. Hepatology 38 (2003) 218-229
10. Simeonova P.P., Gallucci R.M., Hulderman T., Wilson R., Kommineni C., Rao M., et al. The role of tumor necrosis factor-alpha in liver toxicity, inflammation, and fibrosis induced by carbon tetrachloride. Toxicol Appl Pharmacol 177 (2001) 112-120
11. Sanderson N., Factor V., Nagy P., Kopp J., Kondaiah P., Wakefield L., et al. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions. Proc Natl Acad Sci USA 92 (1995) 2572-2576
12. George J., Roulot D., Koteliansky V.E., and Bissell D.M. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci USA 96 (1999) 12719-12724
13. Arias M., Sauer-Lehnen S., Treptau J., Janoschek N., Theuerkauf I., Buettner R., et al. Adenoviral expression of a transforming growth factor-beta1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats. BMC Gastroenterol 3 (2003) 29
14. Duffield J.S., Forbes S.J., Constandinou C.M., Clay S., Partolina M., Vuthoori S., et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest 115 (2005) 56-65
15. Evans G.J., and Cousin M.A. Tyrosine phosphorylation of synaptophysin in synaptic vesicle recycling. Biochem Soc Trans 33 (2005) 1350-1353
16. Cassiman D., van Pelt J., De Vos R., Van Lommel F., Desmet V., Yap S.H., et al. Synaptophysin: a novel marker for human and rat hepatic stellate cells. Am J Pathol 155 (1999) 1831-1839
17. Magness S.T., Bataller R., Yang L., and Brenner D.A. A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations. Hepatology 40 (2004) 1151-1159
18. Brown K.E., Broadhurst K.A., Mathahs M.M., Brunt E.M., and Schmidt W.N. Expression of HSP47, a collagen-specific chaperone, in normal and diseased human liver. Lab Invest 85 (2005) 789-797
19. van de Bovenkamp M., Groothuis G.M., Meijer D.K., Slooff M.J., and Olinga P. Human liver slices as an in vitro model to study toxicity-induced hepatic stellate cell activation in a multicellular milieu. Chem Biol Interact 162 (2006) 62-69
20. Elrick L.J., Leel V., Blaylock M.G., Duncan L., Drever M.R., Strachan G., et al. Generation of a monoclonal human single chain antibody fragment to hepatic stellate cells - a potential mechanism for targeting liver anti-fibrotic therapeutics. J Hepatol 42 (2005) 888-896
21. Novo E., Marra F., Zamara E., Valfre di Bonzo L., Monitillo L., Cannito S., et al. Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans. Gut 55 (2006) 1174-1182
22. McElhiney J., Drever M., Lawton L.A., and Porter A.J. Rapid isolation of a single-chain antibody against the cyanobacterial toxin microcystin-LR by phage display and its use in the immunoaffinity concentration of microcystins from water. Appl Environ Microbiol 68 (2002) 5288-5295
23. Fox M., Gray G., Kavanagh K., Lewis C., and Doyle S. Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development. J Microbiol Methods 56 (2004) 221-230
24. Orr J.G., Leel V., Cameron G.A., Marek C.J., Haughton E.L., Elrick L.J., et al. Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells. Hepatology 40 (2004) 232-242
25. Strachan G., Grant S.D., Learmonth D., Longstaff M., Porter A.J., and Harris W.J. Binding characteristics of anti-atrazine monoclonal antibodies and their fragments synthesised in bacteria and plants. Biosens Bioelectron 13 (1998) 665-673
26. Haughton E.L., Tucker S.J., Marek C.J., Durward E., Leel V., Bascal Z., et al. Pregnane X receptor activators inhibit human hepatic stellate cell transdifferentiation in vitro. Gastroenterology 131 (2006) 194-209
27. Marek C.J., Tucker S.J., Konstantinou D.K., Elrick L.J., Haefner D., Sigalas C., et al. Pregnenolone-16alpha-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms. Biochem J 387 (2005) 601-608
28. Xu L., Hui A.Y., Albanis E., Arthur M.J., O'Byrne S.M., Blaner W.S., et al. Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut 54 (2005) 142-151
29. Hagens W.I., Olinga P., Meijer D.K., Groothuis G.M., Beljaars L., and Poelstra K. Gliotoxin non-selectively induces apoptosis in fibrotic and normal livers. Liver Int 26 (2006) 232-239
30. Elsharkawy A.M., Oakley F., and Mann D.A. The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis. Apoptosis 10 (2005) 927-939
31. Iredale J.P., Benyon R.C., Pickering J., McCullen M., Northrop M., Pawley S., et al. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 102 (1998) 538-549
32. Anselmi K., Stolz D.B., Nalesnik M., Watkins S.C., Kamath R., and Gandhi C.R. Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition. J Hepatol 47 (2007) 103-113
33. Fallowfield J.A., Mizuno M., Kendall T.J., Constandinou C.M., Benyon R.C., Duffield J.S., et al. Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis. J Immunol 178 (2007) 5288-5295
34. Knittel T., Kobold D., Saile B., Grundmann A., Neubauer K., Piscaglia F., et al. Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology 117 (1999) 1205-1221
35. Issa R., Zhou X., Constandinou C.M., Fallowfield J., Millward-Sadler H., Gaca M.D., et al. Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology 126 (2004) 1795-1808
36. Pahl H.L., Krauss B., Schulze-Osthoff K., Decker T., Traenckner E.B., Vogt M., et al. The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB. J Exp Med 183 (1996) 1829-1840
37. Elsharkawy A.M., Wright M.C., Hay R.T., Arthur M.J., Hughes T., Bahr M.J., et al. Persistent activation of nuclear factor-kappaB in cultured rat hepatic stellate cells involves the induction of potentially novel Rel-like factors and prolonged changes in the expression of IkappaB family proteins. Hepatology 30 (1999) 761-769