Bromelain induces cardioprotection against ischemia-reperfusion injury through Akt/FOXO pathway in rat myocardium

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 3, 2008, Pages

  Juhasz, Bela ^a,e   Thirunavukkarasu, Mahesh ^a   Pant, Rima ^a   Zhan, Lijun ^a   Penumathsa, Suresh Varma ^a   Secor Jr , Eric R ^a   Srivastava, Sapna ^a   Raychaudhuri, Utpal ^b   Menon, Venugopal P ^c   Otani, Hajime ^d   Thrall, Roger S ^a   Maulik, Nilanjana ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b JADAVPUR UNIVERSITY   (India)

^c ANNAMALAI UNIVERSITY   (India)

^d School of Medicine   (Japan)

^e UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Ananas comosus; Apoptosis; Forkhead transcription factor; Myocardial infarction

Indexed keywords

BROMELAIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FOXO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA FLOW; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BROMELAINS; CARDIOTONIC AGENTS; CORONARY CIRCULATION; CYTOSOL; FORKHEAD TRANSCRIPTION FACTORS; HEART FUNCTION TESTS; HEART RATE; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; VENTRICULAR FUNCTION, LEFT;

EID: 41549162817     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01005.2007     Document Type: Article

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