Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice

Molecular Vision

Volumn 14, Issue , 2008, Pages 562-571

  Weng, Daniel Y ^a   Zhang, Yujin ^a   Hayashi, Yasuhito ^a   Kuan, Chia Yi ^b   Liu, Chia Yang ^a   Babcock, George ^c,d   Weng, Wei Lan ^b   Schwemberger, Sandy ^c   Kao, Winston W Y ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF CINCINNATI   (United States)

^d SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CRE RECOMBINASE;

ALLELE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORNEA; CROSS BREEDING; DIPLOIDY; DNA MODIFICATION; FEMALE; GAMETOGENESIS; GENE DELETION; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC RECOMBINATION; LOXP SITE; MALE; MOUSE; NONHUMAN; PENETRANCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SEX DIFFERENCE; SPERMATOCYTE; SPERMATOGONIUM; TETRAPLOIDY; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

ALLELES; ANIMALS; CORNEA; EPITHELIUM, CORNEAL; FEMALE; GAMETOGENESIS; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; INTEGRASES; KERATIN-12; MALE; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; RECOMBINATION, GENETIC; SPERMATOGENESIS;

EID: 41549155539     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Porter A. Controlling your losses: conditional gene silencing in mammals. Trends Genet 1998; 14:73-9.
2. Tanifuji-Terai N, Terai K, Hayashi Y, Chikama T, Kao WW. Expression of Keratin 12 and Maturation of Corneal Epithelium during Development and Postnatal Growth. Invest Ophthalmol Vis Sci 2006; 47:545-51.
3. Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999; 21:70-1.
4. Liu CY, Shiraishi A, Kao CW, Converse RL, Funderburgh JL, Corpuz LM, Conrad GW, Kao WW. The cloning of mouse keratocan cDNA and genomic DNA and the characterization of its expression during eye development. J Biol Chem 1998; 273:22584-8.
5. Novak A, Guo C, Yang W, Nagy A, Lobe CG. Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis 2000; 28:147-55.
6. Nakamura T, Colbert MC, Robbins J. Neural crest cells retain multipotential characteristics in the developing valves and label the cardiac conduction system. Circ Res 2006; 98:1547-54.
7. Hebert JM, McConnell SK. Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol 2000; 222:296-306.
8. Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cardiac neural crest. Development 2000; 127:1607-16.
9. Yang X, Li C, Herrera PL, Deng CX. Generation of Smad4/Dpc4 conditional knockout mice. Genesis 2002; 32:80-1.
10. Bhowmick NA, Chytil A, Plieth D, Gorska AE, Dumont N, Shappell S, Washington MK, Neilson EG, Moscs HL. TGF-{beta} Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia. Science 2004; 303:848-51.
11. Chytil A, Magnuson MA, Wright CV, Moses HL. Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis 2002; 32:73-5.
12. Bellve AR. Purification culture, and fractionation of spermatogenic cells. Methods Enzymol 1993: 225:84-113.
13. Malkov M, Fisher Y, Don J. Developmental schedule of the postnatal rat testis determined by flow cytometry. Biol Repred 1998; 59:84-92.
14. Bellve AR, Cavicchia JC, Millette CF, O'Brien DA. Bhatnagar YM, Dym M. Spermatogenic cells of the prepuberal mouse. Isclation and morphological characterization. J Cell Biol 1977; 74:68-85.
15. Lassalle B, Ziyyat A, Testart J, Finaz C, Lefevre A. Flow cytometric method to isolate round spermatids from mouse testis. Hum Reprod 1999; 14:388-94.
16. Amer M, Abd Elnasser T, El Haggar S, Mostafa T, Abdel-Malak G, Zhody W. May-Grunwald-Giemsa stain for detection of spermatogenic cells in the ejaculate: a simple predictive parameter for successful testicular sperm retrieval. Hum Reprod 2001; 16:1427-32.
17. Liu CY, Zhu G, Converse RL, Kao CWC, Nakamura H, Tseng SCG, Mui MM, Seyer J, Justice MJ, Stech ME, Hansen GM, Kao WWY. Characterization and chromosomal localization of the cornea- specific murine keratin gene Krt1.12. J Biol Chem 1994; 269:24627-36.
18. Ramirez A, Page A, Gandarillas A, Zanet J, Pibre S, Vidal M, Tusell L, Genesca A, Whitaker DA, Melton DW, Jorcano JL. A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination. Genesis 2004; 39:52-7.
19. Obendorf M, Meyer R, Henning K, Mitev YA, Schroder J, Patchev VK, Wolf SS. FoxG1, a member of the forkhead family, is a corepressor of the androgen receptor. J Steroid Biochem Mol Biol 2007; 104:195-207.
20. Liu CY, Zhu G, Westerhausen-Larson A, Converse RL, Kao CWC, Sun TT, Kao WWY. Cornea-specific expression of K12 keratin during mouse development. Curr Eye Res 1993; 12:963-74.
21. Liu C, Arar H, Kao C. Kao WW. Identification of a 3.2 kb 5□-flanking region of the murine keratocan gene that directs beta-galactosidase expression in the adult corneal stroma of transgenic mice. Gene 2000; 250:85-96.
22. Liu CY, Birk DE, Hassell JR, Kane B, Kao WW. Keratocan-deficient Mice Display Alterations in Corneal Structure. J Biol Chem 2003; 278:21672-7.
23. Kao WW, Liu CY, Converse RL, Shiraishi A, Kao CW, Ishizaki M, Doetschman T, Duffy J. Keratin 12-deficient mice have fragile corneal epithelia. Invest Ophthalmol Vis Sci 1996, 37:2572-84.
24. Paulsson J. Summing up the noise in gene networks. Nature 2004; 427:415-8.
25. Parr BA, McMahon AP. Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a. Nature 1998; 395:707-10.
26. Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol 1998; 8:1323-6.
27. Braun RE, Behringer RR, Peschon JJ, Brinster RL, Palmiter P.D. Genetically haploid spermatids are phenotypically diploid. Nature 1989; 337:373-6.
28. Ramaesh T, Collinson JM, Ramaesh K, Kaufman MH, West JD, Dhillon B. Corneal abnormalities in Pax6+/ small eye mice mimic human aniridia-related keratopathy. Invest Ophthalmol Vis Sci 2003; 44:1871-8.
29. Segev F, Heon E, Cole WG, Wenstrup RJ, Young F, Slomovic AR, Rootman DS, Whitaker-Menezes D, Chervoneva I, Birk DE. Structural abnormalities of the cornea and lid resulting from collagen V mutations. Invest Ophthalmol Vis Sci 2006; 47:563-73.