Detection of human herpesviruses HHV-6, HHV-7 and HHV-8 in whole blood by real-time PCR using the new CMV, HHV-6, 7, 8 R-gene™ kit

Journal of Virological Methods

Volumn 149, Issue 2, 2008, Pages 285-291

  Deback, C ^a   Agbalika, F ^b,c   Scieux, C ^b,c   Marcelin, A G ^a   Gautheret Dejean, A ^a   Cherot, J ^b   Hermet, L ^a   Roger, O ^a   Agut, H ^a  

^a UPRES EA 2387   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Human herpesvirus 6; Human herpesvirus 7; Human herpesvirus 8; Real time PCR; Whole blood

Indexed keywords

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DIAGNOSTIC PROCEDURE; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 7; HUMAN HERPESVIRUS 8; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS DETECTION;

BLOOD; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 6, HUMAN; HERPESVIRUS 7, HUMAN; HERPESVIRUS 8, HUMAN; HUMANS; POLYMERASE CHAIN REACTION; ROSEOLOVIRUS INFECTIONS; SENSITIVITY AND SPECIFICITY;

HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 7; HUMAN HERPESVIRUS 8;

EID: 41549153663     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2008.01.026     Document Type: Article

References (28)

1. Agut H., Dupin N., Aubin J.T., and Calvez V. Novel human herpesviruses (human herpesviruses 6, 7 and 8). Clin Microbiol Infect 2 (1996) 159-167
2. Berneman Z.N., Ablashi D.V., Li G., Eger-Fletcher M., Reitz Jr. M.S., Hung C.L., Brus I., Komaroff A.L., and Gallo R.C. Human herpesvirus 7 is a T-lymphotropic virus and is related to, but significantly different from, human herpesvirus 6 and human cytomegalovirus. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 10552-10556
3. Boutolleau D., Bonduelle O., Agut H., and Gautheret-Dejean A. Is human herpesvirus-7 a marker or a competitor for HIV progression?. Aids 18 (2004) 358-359
4. + cell count in patients infected with HIV. J. Med. Virol. 76 (2005) 223-228
5. Boutolleau D., Fernandez C., Andre E., Imbert-Marcille B.M., Milpied N., Agut H., and Gautheret-Dejean A. Human herpesvirus (HHV)-6 and HHV-7: two closely related viruses with different infection profiles in stem cell transplantation recipients. J. Infect. Dis. 187 (2003) 179-186
6. Caserta M.T., Mock D.J., and Dewhurst S. Human herpesvirus 6. Clin. Infect. Dis. 33 (2001) 829-833
7. Cermelli C., Fabio G., Montorsi M., Sabbatini A.M., and Portolani M. Prevalence of antibodies to human herpesviruses 6 and 7 in early infancy and age at primary infection. New Microbiol. 19 (1996) 1-8
8. Clark D.A., Nacheva E.P., Leong H.N., Brazma D., Li Y.T., Tsao E.H., Buyck H.C., Atkinson C.E., Lawson H.M., Potter M.N., and Griffiths P.D. Transmission of integrated human herpesvirus 6 through stem cell transplantation: implications for laboratory diagnosis. J. Infect. Dis. 193 (2006) 912-916
9. Franti M., Gessain A., Darlu P., Gautheret-Dejean A., Kosuge H., Mauclere P., Aubin J.T., Gurtsevitch V., Yamanishi K., and Agut H. Genetic polymorphism of human herpesvirus-7 among human populations. J. Gen. Virol. 82 (2001) 3045-3050
10. Gautheret-Dejean A., Aubin J.T., Poirel L., Huraux J.M., Nicolas J.C., Rozenbaum W., and Agut H. Detection of human Betaherpesvirinae in saliva and urine from immunocompromised and immunocompetent subjects. J. Clin. Microbiol. 35 (1997) 1600-1603
11. Gautheret-Dejean A., Manichanh C., Thien-Ah-Koon F., Fillet A.M., Mangeney N., Vidaud M., Dhedin N., Vernant J.P., and Agut H. Development of a real-time polymerase chain reaction assay for the diagnosis of human herpesvirus-6 infection and application to bone marrow transplant patients. J. Virol. Methods 100 (2002) 27-35
12. Ginanneschi F., Donati D., Moschettini D., Dominici F., Cermelli C., and Rossi A. Encephaloradiculomyelitis associated to HHV-7 and CMV co-infection in immunocompetent host. Clin. Neurol. Neurosurg. 109 (2007) 272-276
13. Gouarin S., Vabret A., Scieux C., Agbalika F., Cherot J., Mengelle C., Deback C., Petitjean J., Dina J., and Freymuth F. Multicentric evaluation of a new commercial cytomegalovirus real-time PCR quantitation assay. J. Virol. Methods 146 (2007) 147-154
14. Hall C.B., Caserta M.T., Schnabel K.C., McDermott M.P., Lofthus G.K., Carnahan J.A., Gilbert L.M., and Dewhurst S. Characteristics and acquisition of human herpesvirus (HHV) 7 infections in relation to infection with HHV-6. J. Infect. Dis. 193 (2006) 1063-1069
15. Hermouet S., Sutton C.A., Rose T.M., Greenblatt R.J., Corre I., Garand R., Neves A.M., Bataille R., and Casey J.W. Qualitative and quantitative analysis of human herpesviruses in chronic and acute B cell lymphocytic leukemia and in multiple myeloma. Leukemia 17 (2003) 185-195
16. Imbert-Marcille B.M., Tang X.W., Lepelletier D., Besse B., Moreau P., Billaudel S., and Milpied N. Human herpesvirus 6 infection after autologous or allogeneic stem cell transplantation: a single-center prospective longitudinal study of 92 patients. Clin. Infect. Dis. 31 (2000) 881-886
17. Kangro H.O., Osman H.K., Lau Y.L., Heath R.B., Yeung C.Y., and Ng M.H. Seroprevalence of antibodies to human herpesviruses in England and Hong Kong. J. Med. Virol. 43 (1994) 91-96
18. Lallemand F., Desire N., Rozenbaum W., Nicolas J.C., and Marechal V. Quantitative analysis of human herpesvirus 8 viral load using a real-time PCR assay. J. Clin. Microbiol. 38 (2000) 1404-1408
19. Le Cleach L., Joberty C., Fillet A.M., Sutton L., Cordonnier C., Frances C., Agut H., and Chosidow O. Human herpesvirus 6 infection in patients with exanthema after allogeneic bone marrow transplantation. Arch. Dermatol. 134 (1998) 759-760
20. Ljungman P. Beta-herpesvirus challenges in the transplant recipient. J. Infect. Dis. 186 suppl. 1 (2002) S99-S109
21. Ljungman P., Wang F.Z., Clark D.A., Emery V.C., Remberger M., Ringden O., and Linde A. High levels of human herpesvirus 6 DNA in peripheral blood leucocytes are correlated to platelet engraftment and disease in allogeneic stem cell transplant patients. Br. J. Haematol. 111 (2000) 774-781
22. Mesri E.A., Cesarman E., Arvanitakis L., Rafii S., Moore M.A., Posnett D.N., Knowles D.M., and Asch A.S. Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells. J. Exp. Med. 183 (1996) 2385-2390
23. Moore P.S., Gao S.J., Dominguez G., Cesarman E., Lungu O., Knowles D.M., Garber R., Pellett P.E., McGeoch D.J., and Chang Y. Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae. J. Virol. 70 (1996) 549-558
24. Oksenhendler E., Carcelain G., Aoki Y., Boulanger E., Maillard A., Clauvel J.P., and Agbalika F. High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients. Blood 96 (2000) 2069-2073
25. Rieux C., Gautheret-Dejean A., Challine-Lehmann D., Kirch C., Agut H., and Vernant J.P. Human herpesvirus-6 meningoencephalitis in a recipient of an unrelated allogeneic bone marrow transplantation. Transplantation 65 (1998) 1408-1411
26. Takahashi K., Sonoda S., Higashi K., Kondo T., Takahashi H., Takahashi M., and Yamanishi K. Predominant CD4 T-lymphocyte tropism of human herpesvirus 6-related virus. J. Virol. 63 (1989) 3161-3163
27. Vega F., Chang C.C., Medeiros L.J., Udden M.M., Cho-Vega J.H., Lau C.C., Finch C.J., Vilchez R.A., McGregor D., and Jorgensen J.L. Plasmablastic lymphomas and plasmablastic plasma cell myelomas have nearly identical immunophenotypic profiles. Mod. Pathol. 18 (2005) 806-815
28. Zerr D.M., Gooley T.A., Yeung L., Huang M.L., Carpenter P., Wade J.C., Corey L., and Anasetti C. Human herpesvirus 6 reactivation and encephalitis in allogeneic bone marrow transplant recipients. Clin. Infect. Dis. 33 (2001) 763-771