Encephaloradiculomyelitis associated to HHV-7 and CMV co-infection in immunocompetent host

Clinical Neurology and Neurosurgery

Volumn 109, Issue 3, 2007, Pages 272-276

  Ginanneschi, Federica ^a   Donati, Donatella ^a   Moschettini, Donatella ^a   Dominici, Federica ^a   Cermelli, Claudio ^b   Rossi, Alessandro ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

CMV; Encephaloradiculomyelitis; HHV 7; Immunocompetence; Immunodepression

Indexed keywords

CHLORAMPHENICOL; DEXAMETHASONE; GANCICLOVIR; PENICILLIN G; VIRUS DNA;

ADULT; ARTICLE; CASE REPORT; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID ANALYSIS; CLINICAL FEATURE; CYTOMEGALOVIRUS; ELECTROMYOGRAM; ENCEPHALORADICULOMYELITIS; HUMAN; HUMAN HERPESVIRUS 7; IMMUNOCOMPETENCE; IMMUNODIFFUSION; MALE; MYELITIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL BLOOD MONONUCLEAR CELL; PERIPHERAL NEUROPATHY; POLYMERASE CHAIN REACTION; THORAX RADIOGRAPHY;

COMORBIDITY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA PRIMERS; DNA, VIRAL; ENCEPHALITIS, VIRAL; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 7, HUMAN; HUMANS; IMMUNOCOMPETENCE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; MYELITIS; POLYMERASE CHAIN REACTION; RADICULOPATHY;

EID: 33847021464     PISSN: 03038467     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clineuro.2006.04.002     Document Type: Article

References (17)

1. Ward K.N., Andrews N.J., Verity C.M., Miller E., and Ross E.M. Human herpesvirus -6 and -7 each cause significant neurological morbidity in Britain and Ireland. Arch Dis Child 90 (2005) 619-623
2. Maschke M., Kastrup O., and Diener H.C. CNS manifestations of Cytomegalovirus infections: diagnosis and treatment. CNS Drugs 16 (2002) 303-315
3. Razonable R.R., Rivero A., Brown R.A., Hart G.D., Espy M.J., van Cruijsen H., et al. Detection of simultaneous beta-herpesvirus infections in clinical syndromes due to defined cytomegalovirus infection. Clin Transplant 17 (2003) 114-120
4. Ward K.N., Kalima P., MacLeod K.M., and Riordan T. Neuroinvasion during delayed primary infection in an immunocompetent adult with encephalitic and flaccid paralysis. J Med Virol 67 (2002) 538-541
5. Tanaka-taya K., Kondo T., Mukai T., Miyoshi H., Yamamoto Y., Okada S., et al. Seroepidemiological study of human herpesvirus-6 and -7 in children of different ages and detection of these two viruses in throat swabs by polymerase chain reaction. J Med Virol 48 (1996) 88-94
6. Cermelli C., Fabio G., Montorsi M., Sabbatini A.M., and Portolani M. Prevalence of antibodies to human herpesvirus 6 and 7 in early infancy and age at primary infection. New Microbiol 19 (1996) 1-8
7. Boiving G. Diagnosis of herpesvirus infections of the central nervous system. Herpes 11 (2004) 48A-56A
8. Sanders V.J., Felisan S., Waddell A., and Tourtellotte W.W. Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction. J Neurovirol 2 (1996) 249-258
9. Chan P.K., Ng H.K., Cheung J.L., Ng K.C., and Cheng A.F. Prevalence and distribution of human herpesvirus 7 in normal brain. J Med Virol 62 (2000) 345-348
10. Chapenko S., Folkmane I., Tomsone V., Amerika D., Rozentals R., and Murovska M. Co-infection of two beta-herpesviruses (CMV and HHV-7) as an increased risk factor for 'CMV disease' in patients undergoing renal transplantation. Clin Transplant 14 (2000) 486-492
11. Fux C.A., Pfister S., Nohl F., and Zimmerli S. Cytomegalovirus-associated acute transverse myelitis in immunocompetent adults. Clin Microbio Infect 9 (2003) 1187-1190
12. Rigamonti A., Usai S., Ciusani E., and Bussone G. Atypical transverse myelitis due to cytomegalovirus in an immunocompetent patient. Neurol Sci 26 (2005) 351-354
13. Ward K.N., White R.P., Mackinnon S., and Hanna M. Human herpesvirus-7 infection of the CNS with acute myelitis in an adult bone marrow recipient. Bone Marrow Transplant 30 (2002) 983-985
14. Secchiero P., Flamand L., Gibellini D., Falcieri E., Robuffo I., Capitani S., et al. Human Herpesvirus 7 induces CD4 (+) T-cell death by two distinct mechanisms: necrotic lysis in productively infected cells and apoptosis in uninfected or nonproductively infected cells. Blood 90 (1997) 4502-4512
15. Atedzoe B.N., Menezes J., D'addario M., Xu J., Ongradi J., and Ahmad A. Modulatory effects of human herpes virus-7 on cytokine synthesis and cell proliferation in human peripheral blood mononuclear cell cultures. J Leukoc Biol 66 (1999) 822-828
16. Tadagaki K., Nakano K., and Yamanishi K. Human HHV-7 Open Reading Frames U12 and U51 Encode Functional-Chemokine Receptors. J Virol 79 (2005) 7068-7076
17. Frenkel N., and Wyatt L.S. HHV-6 and HHV-7 as exogenous agent in human lymphocytes. Dev Biol Stand 76 (1992) 259-265