Intracellular delivery of peptides via association with ubiquitin or SUMO-1 coupled to protein transduction domains

BMC Biotechnology

Volumn 8, Issue , 2008, Pages

  Vitte, Anne Laure ^a   Jalinot, Pierre ^a  

^a UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BIOCHEMISTRY; POLYPEPTIDES; PROTEINS;

BACTERIAL EXPRESSION VECTORS; CYTOSOL; DIGLYCINE MOTIF; HUMAN UBIQUITIN; PROTEIN TRANSDUCTION DOMAIN;

PEPTIDES;

ARGININE; DIGLYCINE; EPITOPE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LYSINE; POLYARGININE; SUMO 1 PROTEIN; TRANSACTIVATOR PROTEIN; UBIQUITIN; PEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FRACTIONATION; CONTROLLED STUDY; CYTOSOL; ESCHERICHIA COLI; EXPRESSION VECTOR; IMMUNOFLUORESCENCE; INTRACELLULAR TRANSPORT; MUTATION; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN TRANSPORT; WILD TYPE; GENETIC TRANSDUCTION; GENETICS; HUMAN; LEUKEMIA CELL LINE; METABOLISM; METHODOLOGY; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE;

BACTERIA (MICROORGANISMS); HUMAN IMMUNODEFICIENCY VIRUS 1;

GENE PRODUCTS, TAT; HUMANS; JURKAT CELLS; PEPTIDES; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SUMO-1 PROTEIN; TRANSDUCTION, GENETIC; UBIQUITIN;

EID: 41549136894     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-8-24     Document Type: Article

References (32)

1. Frankel AD Pabo CO Cellular uptake of the tat protein from human immunodeficiency virus Cell 1988, 55(6):1189-1193 10.1016/ 0092-8674(88)90263-2 2849510
2. Green M Loewenstein PM Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein Cell 1988, 55(6):1179-1188 10.1016/0092-8674(88)90262-0 2849509
3. Joliot A Pernelle C Deagostini-Bazin H Prochiantz A Antennapedia homeobox peptide regulates neural morphogenesis Proc Natl Acad Sci U S A 1991, 88(5):1864-1868 51126 1672046 10.1073/pnas.88.5.1864
4. Fawell S Seery J Daikh Y Moore C Chen LL Pepinsky B Barsoum J Tat-mediated delivery of heterologous proteins into cells Proc Natl Acad Sci U S A 1994, 91(2):664-668 43009 8290579 10.1073/pnas.91.2.664
5. Pepinsky RB Androphy EJ Corina K Brown R Barsoum J Specific inhibition of a human papillomavirus E2 trans-activator by intracellular delivery of its repressor DNA Cell Biol 1994, 13(10):1011-1019 7945933
6. Perez F Joliot A Bloch-Gallego E Zahraoui A Triller A Prochiantz A Antennapedia homeobox as a signal for the cellular internalization and nuclear addressing of a small exogenous peptide J Cell Sci 1992, 102 (Pt 4):717-722 1358900
7. Chauhan A Tikoo A Kapur AK Singh M The taming of the cell penetrating domain of the HIV Tat: Myths and realities J Control Release 2007, 117(2):148-162 1859861 17196289 10.1016/j.jconrel.2006.10.031
8. Schwarze SR Ho A Vocero-Akbani A Dowdy SF In vivo protein transduction: delivery of a biologically active protein into the mouse Science 1999, 285(5433):1569-1572 10.1126/science.285.5433.1569 10477521
9. Leifert JA Harkins S Whitton JL Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity Gene Ther 2002, 9(21):1422-1428 10.1038/sj.gt.3301819 12378404
10. Leifert JA Whitton JL "Translocatory proteins" and "protein transduction domains": A critical analysis of their biological effects and the underlying mechanisms Mol Ther 2003, 8(1):13-20 10.1016/S1525-0016(03)00151-5 12842424
11. Lundberg M Johansson M Is VP22 nuclear homing an artifact? Nat Biotechnol 2001, 19(8):713-714 10.1038/90741 11479552
12. Thoren PE Persson D Isakson P Goksor M Onfelt A Norden B Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells Biochem Biophys Res Commun 2003, 307(1):100-107 10.1016/ S0006-291X(03)01135-5 12849987
13. Nagahara H Vocero-Akbani AM Snyder EL Ho A Latham DG Lissy NA Becker-Hapak M Ezhevsky SA Dowdy SF Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration Nat Med 1998, 4(12):1449-1452 10.1038/4042 9846587
14. Roisin A Robin JP Dereuddre-Bosquet N Vitte AL Dormont D Clayette P Jalinot P Inhibition of HIV-1 replication by cell-penetrating peptides binding Rev J Biol Chem 2004, 279(10):9208-9214 10.1074/jbc.M311594200 14668323
15. Wadia JS Stan RV Dowdy SF Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis Nat Med 2004, 10(3):310-315 10.1038/nm996 14770178
16. Dom G Shaw-Jackson C Matis C Bouffioux O Picard JJ Prochiantz A Mingeot-Leclercq MP Brasseur R Rezsohazy R Cellular uptake of Antennapedia Penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation Nucleic Acids Res 2003, 31(2):556-561 140524 12527762 10.1093/nar/gkg160
17. Richard JP Melikov K Brooks H Prevot P Lebleu B Chernomordik LV Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors J Biol Chem 2005, 280(15):15300-15306 10.1074/jbc.M401604200 15687490
18. Richard JP Melikov K Vives E Ramos C Verbeure B Gait MJ Chernomordik LV Lebleu B Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake J Biol Chem 2003, 278(1):585-590 10.1074/jbc.M209548200 12411431
19. Vives E Richard JP Rispal C Lebleu B TAT peptide internalization: seeking the mechanism of entry Curr Protein Pept Sci 2003, 4(2):125-132 10.2174/1389203033487306 12678851
20. Baker RT Protein expression using ubiquitin fusion and cleavage Curr Opin Biotechnol 1996, 7(5):541-546 10.1016/S0958-1669(96)80059-0 8939629
21. Baker RT Smith SA Marano R McKee J Board PG Protein expression using cotranslational fusion and cleavage of ubiquitin. Mutagenesis of the glutathione-binding site of human Pi class glutathione S-transferase J Biol Chem 1994, 269(41):25381-25386 7929235
22. Hondred D Walker JM Mathews DE Vierstra RD Use of ubiquitin fusions to augment protein expression in transgenic plants Plant Physiol 1999, 119(2):713-724 32149 9952468 10.1104/pp.119.2.713
23. Pilon A Yost P Chase TE Lohnas G Burkett T Roberts S Bentley WE Ubiquitin fusion technology: Bioprocessing of peptides Biotechnol Prog 1997, 13(4):374-379 10.1021/bp970040f 9265776
24. Yoo Y Rote K Rechsteiner M Synthesis of peptides as cloned ubiquitin extensions J Biol Chem 1989, 264(29):17078-17083 2551894
25. Bachmair A Finley D Varshavsky A In vivo half-life of a protein is a function of its amino-terminal residue Science 1986, 234(4773):179-186 10.1126/science.3018930 3018930
26. Futaki S Suzuki T Ohashi W Yagami T Tanaka S Ueda K Sugiura Y Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery J Biol Chem 2001, 276(8):5836-5840 10.1074/jbc.M007540200 11084031
27. Varshavsky A The early history of the ubiquitin field Protein Sci 2006, 15(3):647-654 10.1110/ps.052012306 16501229 2249785
28. Ho A Schwarze SR Mermelstein SJ Waksman G Dowdy SF Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo Cancer Res 2001, 61(2):474-477 11212234
29. Loison F Nizard P Sourisseau T Le Goff P Debure L Le Drean Y Michel D A ubiquitin-based assay for the cytosolic uptake of protein transduction domains Mol Ther 2005, 11(2):205-214 10.1016/j.ymthe.2004.10.010 15668132
30. Kawakami T Suzuki T Baek SH Chung CH Kawasaki H Hirano H Ichiyama A Omata M Tanaka K Isolation and characterization of cytosolic and membrane-bound deubiquitinylating enzymes from bovine brain J Biochem (Tokyo) 1999, 126(3):612-623 10467179
31. Sekiguchi S Kwon J Yoshida E Hamasaki H Ichinose S Hideshima M Kuraoka M Takahashi A Ishii Y Kyuwa S Wada K Yoshikawa Y Localization of ubiquitin C-terminal hydrolase L1 in mouse ova and its function in the plasma membrane to block polyspermy Am J Pathol 2006, 169(5):1722-1729 1780224 17071595 10.2353/ajpath.2006.060301
32. Hay RT SUMO-specific proteases: A twist in the tail Trends Cell Biol 2007, 17(8):370-376 10.1016/j.tcb.2007.08.002 17768054