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Volumn 17, Issue 3, 2008, Pages 578-584

Progestin treatment induces apoptosis and modulates transforming growth factor-β in the uterine endometrium

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CONJUGATED ESTROGEN; KI 67 ANTIGEN; MEDROXYPROGESTERONE ACETATE; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

EID: 41549135945     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-07-0551     Document Type: Article
Times cited : (29)

References (77)
  • 2
    • 41549144479 scopus 로고    scopus 로고
    • American Cancer Society. Cancer facts and figures 2006. Atlanta: American Cancer; 2006.
    • American Cancer Society. Cancer facts and figures 2006. Atlanta: American Cancer; 2006.
  • 3
    • 0020619091 scopus 로고
    • The epidemiology of endometrial cancer in young women
    • Henderson BE, Casagrance JT, Pike MC, et al. The epidemiology of endometrial cancer in young women. Br J Cancer 1983;47:749-56.
    • (1983) Br J Cancer , vol.47 , pp. 749-756
    • Henderson, B.E.1    Casagrance, J.T.2    Pike, M.C.3
  • 5
    • 0001657785 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on endometrial histology in postmenopausal women: The Postmenopausal Estrogen/Progestin Interventions (PEPI) trial
    • The Writing Group for the PEPI trial
    • The Writing Group for the PEPI trial. Effects of hormone replacement therapy on endometrial histology in postmenopausal women: the Postmenopausal Estrogen/Progestin Interventions (PEPI) trial. JAMA 1996;275:370-5.
    • (1996) JAMA , vol.275 , pp. 370-375
  • 6
    • 32144440774 scopus 로고    scopus 로고
    • Weight history and risk of endometrial cancer among Chinese women
    • Xu W, Xiang Y-B, Zheng W, et al. Weight history and risk of endometrial cancer among Chinese women. Int J Epidemiol 2006;35:159-66.
    • (2006) Int J Epidemiol , vol.35 , pp. 159-166
    • Xu, W.1    Xiang, Y.-B.2    Zheng, W.3
  • 8
    • 0033973417 scopus 로고    scopus 로고
    • Body size in different periods of life, diabetes mellitus, hypertension, and risk of postmenopausal endometrial cancer (Sweden)
    • Weiderpass E, Persson I, Adami HO, Magnusson C, Lindgren A, Baron JA. Body size in different periods of life, diabetes mellitus, hypertension, and risk of postmenopausal endometrial cancer (Sweden). Cancer Causes Control 2000;11:185-92.
    • (2000) Cancer Causes Control , vol.11 , pp. 185-192
    • Weiderpass, E.1    Persson, I.2    Adami, H.O.3    Magnusson, C.4    Lindgren, A.5    Baron, J.A.6
  • 9
    • 0036244677 scopus 로고    scopus 로고
    • Safety and efficacy of a continuous once-a-week 17β-estradiol/levonorgestrel transdermal system and its effects on vasomotor symptoms and endometrial safety in postmenopausal women: The results of two multicenter, double-blind, randomized, controlled trials
    • Shulman LP, Yankov V, Uhl K. Safety and efficacy of a continuous once-a-week 17β-estradiol/levonorgestrel transdermal system and its effects on vasomotor symptoms and endometrial safety in postmenopausal women: the results of two multicenter, double-blind, randomized, controlled trials. Menopause 2002;9:195-207.
    • (2002) Menopause , vol.9 , pp. 195-207
    • Shulman, L.P.1    Yankov, V.2    Uhl, K.3
  • 10
    • 32144441470 scopus 로고    scopus 로고
    • Commentary: Weight gain, weight loss, and endometrial cancer
    • Webb PM. Commentary: Weight gain, weight loss, and endometrial cancer. Int J Epidemiol 2006;35:166-8.
    • (2006) Int J Epidemiol , vol.35 , pp. 166-168
    • Webb, P.M.1
  • 11
    • 33746921186 scopus 로고    scopus 로고
    • Oral contraceptive use and cancer. Findings in a large cohort study, 1968-2004
    • Vessey M, Painter R. Oral contraceptive use and cancer. Findings in a large cohort study, 1968-2004. Br J Cancer 2006;95:385-9.
    • (2006) Br J Cancer , vol.95 , pp. 385-389
    • Vessey, M.1    Painter, R.2
  • 13
    • 0023155215 scopus 로고
    • Combination oral contraceptive use and the risk of endometrial cancer
    • The Cancer and Steroid Hormone (CASH) Study of the Centers for Disease Control and the National Institute of Child Health and Human Development
    • The Cancer and Steroid Hormone (CASH) Study of the Centers for Disease Control and the National Institute of Child Health and Human Development. Combination oral contraceptive use and the risk of endometrial cancer. J Am Med Assoc 1987;257:796-800.
    • (1987) J Am Med Assoc , vol.257 , pp. 796-800
  • 14
    • 0023782978 scopus 로고
    • The WHO collaborative study of neoplasia and steroid contraceptives. Endometrial cancer and combined oral contraceptives
    • The WHO collaborative study of neoplasia and steroid contraceptives. Endometrial cancer and combined oral contraceptives. Int J Epidemiol 1988;17:263-9.
    • (1988) Int J Epidemiol , vol.17 , pp. 263-269
  • 15
    • 0027519355 scopus 로고
    • Oral contraceptives and endometrial cancer
    • Jick SS, Walker AM, Jick H. Oral contraceptives and endometrial cancer. Obstet Gynecol 1993;82:931-5.
    • (1993) Obstet Gynecol , vol.82 , pp. 931-935
    • Jick, S.S.1    Walker, A.M.2    Jick, H.3
  • 16
    • 33750185427 scopus 로고    scopus 로고
    • Progestin and estrogen potency of combination oral contraceptives and endometrial cancer risk
    • Maxwell GL, Schildkraut JM, Calingaert B, et al. Progestin and estrogen potency of combination oral contraceptives and endometrial cancer risk. Gynecol Oncol 2006;103:535-40.
    • (2006) Gynecol Oncol , vol.103 , pp. 535-540
    • Maxwell, G.L.1    Schildkraut, J.M.2    Calingaert, B.3
  • 17
    • 0025840335 scopus 로고
    • WHO Collaborative Study of Neoplasia and Steroid Contraceptives. Hormonal content of combined oral contraceptives in relation to the reduced risk of endometrial carcinoma
    • Rosenblatt KA, Thomas DB; WHO Collaborative Study of Neoplasia and Steroid Contraceptives. Hormonal content of combined oral contraceptives in relation to the reduced risk of endometrial carcinoma. Int J Cancer 1991;49:870-4.
    • (1991) Int J Cancer , vol.49 , pp. 870-874
    • Rosenblatt, K.A.1    Thomas, D.B.2
  • 19
    • 33748852718 scopus 로고    scopus 로고
    • Oral contraceptive and IUD use and endometrial cancer: A population-based case-control study in Shanghai, China
    • Tao MH, Xu WH, Zheng W, et al. Oral contraceptive and IUD use and endometrial cancer: a population-based case-control study in Shanghai, China. Int J Cancer 2006;119:2142-7.
    • (2006) Int J Cancer , vol.119 , pp. 2142-2147
    • Tao, M.H.1    Xu, W.H.2    Zheng, W.3
  • 20
    • 33745289011 scopus 로고    scopus 로고
    • Regression of latent endometrial precancers by progestin infiltrated intrauterine device
    • Orbo A, Rise CE, Mutter G. Regression of latent endometrial precancers by progestin infiltrated intrauterine device. Cancer Res 2006;66:5613-7.
    • (2006) Cancer Res , vol.66 , pp. 5613-5617
    • Orbo, A.1    Rise, C.E.2    Mutter, G.3
  • 21
    • 0030797584 scopus 로고    scopus 로고
    • Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age 40
    • Randall TC, Kurman RJ. Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age 40. Obstet Gynecol 1997;90:434-40.
    • (1997) Obstet Gynecol , vol.90 , pp. 434-440
    • Randall, T.C.1    Kurman, R.J.2
  • 22
    • 20444456570 scopus 로고    scopus 로고
    • Vereide AB, Kaino T, Sager G, Ørbo A. Bcl-2, BAX, and apoptosis in endometrial hyperplasia after high dose gestagen therapy: a comparison of responses in patients treated with intrauterine levonorgestrel and systemic medroxyprogesterone. Gynecol Oncol 2005;97:740-50.
    • Vereide AB, Kaino T, Sager G, Ørbo A. Bcl-2, BAX, and apoptosis in endometrial hyperplasia after high dose gestagen therapy: a comparison of responses in patients treated with intrauterine levonorgestrel and systemic medroxyprogesterone. Gynecol Oncol 2005;97:740-50.
  • 23
    • 0037005938 scopus 로고    scopus 로고
    • Progestin-induced apoptosis in the macaque ovarian epithelium: Differential regulation of transforming growth factor-β
    • Rodriguez GC, Nagarsheth NP, Lee KL, et al. Progestin-induced apoptosis in the macaque ovarian epithelium: differential regulation of transforming growth factor-β. J Natl Cancer Inst 2002;94:50-60.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 50-60
    • Rodriguez, G.C.1    Nagarsheth, N.P.2    Lee, K.L.3
  • 25
    • 0027050477 scopus 로고
    • Collaborative Ovarian Cancer Group. Characteristics relating to ovarian cancer risk: Collaborative analysis of 12 US case-control studies. IV. The pathogenesis of epithelial ovarian cancer
    • Whittemore AS, Harris R, Itnyre J; Collaborative Ovarian Cancer Group. Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. IV. The pathogenesis of epithelial ovarian cancer. Am J Epidemiol 1992;136:1212-20.
    • (1992) Am J Epidemiol , vol.136 , pp. 1212-1220
    • Whittemore, A.S.1    Harris, R.2    Itnyre, J.3
  • 27
    • 0035145605 scopus 로고    scopus 로고
    • Cline JM, Söderqvist G, Register TC, Williams JK, Adams MR, Von Schoultz B. Assessment of hormonally active agents in the reproductive tract of female nonhuman primates. Toxicol Pathol 2001;29:84-90.
    • Cline JM, Söderqvist G, Register TC, Williams JK, Adams MR, Von Schoultz B. Assessment of hormonally active agents in the reproductive tract of female nonhuman primates. Toxicol Pathol 2001;29:84-90.
  • 28
    • 0000760138 scopus 로고
    • Cyclic changes in the primate oviduct and endometrium
    • Knobil E, Neill JD, editors, New York NY, Raven Press;
    • Brenner RM, Slayden OD. Cyclic changes in the primate oviduct and endometrium. In: Knobil E, Neill JD, editors. The physiology of reproduction. New York (NY): Raven Press; 1994. p. 541-69.
    • (1994) The physiology of reproduction , pp. 541-569
    • Brenner, R.M.1    Slayden, O.D.2
  • 29
    • 0022449404 scopus 로고
    • Dosage regimen design for pharmaceutical studies conducted in animals
    • Mordenti J. Dosage regimen design for pharmaceutical studies conducted in animals. J Pharm Sci 1986;75:852-7.
    • (1986) J Pharm Sci , vol.75 , pp. 852-857
    • Mordenti, J.1
  • 30
    • 0035707994 scopus 로고    scopus 로고
    • Biological effects of hormone replacement therapy in relation to serum estradiol levels
    • Yasui T, Uemura H, Tezuka M, Yamada M, Irahara M, Miura M, Aono T. Biological effects of hormone replacement therapy in relation to serum estradiol levels. Horm Res 2001;56:38-44.
    • (2001) Horm Res , vol.56 , pp. 38-44
    • Yasui, T.1    Uemura, H.2    Tezuka, M.3    Yamada, M.4    Irahara, M.5    Miura, M.6    Aono, T.7
  • 31
    • 0031897755 scopus 로고    scopus 로고
    • Effects of conjugated estrogens, medroxyprogesterone acetate, and tamoxifen on the mammary glands of macaques
    • Cline JM, Söderqvist G, von Schoultz E, Skoog L, von Schoultz B. Effects of conjugated estrogens, medroxyprogesterone acetate, and tamoxifen on the mammary glands of macaques. Breast Cancer Res Treat 1998;48:221-9.
    • (1998) Breast Cancer Res Treat , vol.48 , pp. 221-229
    • Cline, J.M.1    Söderqvist, G.2    von Schoultz, E.3    Skoog, L.4    von Schoultz, B.5
  • 32
    • 22244432847 scopus 로고    scopus 로고
    • Conner P, Register TC, Skoog L, Tani E, von Schoultz Cline JM. Expression of p53 and markers for apoptosis in breast tissue during long-term hormone therapy in cynomolgus monkeys. Am J Obstet Gynecol 2005;193:58-63.
    • Conner P, Register TC, Skoog L, Tani E, von Schoultz Cline JM. Expression of p53 and markers for apoptosis in breast tissue during long-term hormone therapy in cynomolgus monkeys. Am J Obstet Gynecol 2005;193:58-63.
  • 34
    • 0033762272 scopus 로고    scopus 로고
    • Apoptosis may be an early event of progestin therapy for endometrial hyperplasia
    • Amezcua CA, Lu JJ, Felix JC, Stanczyk FZ, Zheng W. Apoptosis may be an early event of progestin therapy for endometrial hyperplasia. Gynecol Oncol 2000;79:169-76.
    • (2000) Gynecol Oncol , vol.79 , pp. 169-176
    • Amezcua, C.A.1    Lu, J.J.2    Felix, J.C.3    Stanczyk, F.Z.4    Zheng, W.5
  • 35
    • 0029895510 scopus 로고    scopus 로고
    • Effect of decidualization on the expression of bax and bcl-2 in the rat uterine endometrium
    • Akcali KC, Khan SA, Moulton BC. Effect of decidualization on the expression of bax and bcl-2 in the rat uterine endometrium. Endocrinology 1996;137:3123-31.
    • (1996) Endocrinology , vol.137 , pp. 3123-3131
    • Akcali, K.C.1    Khan, S.A.2    Moulton, B.C.3
  • 36
    • 20044384893 scopus 로고    scopus 로고
    • Molecular portrait of the progestagenic and estrogenic actions of tibolone: Behavior of cellular networks in response to tibolone
    • Hanifi-Moghaddam, Gielen SC, Kloosterboer HJ, et al. Molecular portrait of the progestagenic and estrogenic actions of tibolone: behavior of cellular networks in response to tibolone. J Clin Endocrinol Metabol 2005;90:973-83.
    • (2005) J Clin Endocrinol Metabol , vol.90 , pp. 973-983
    • Moghaddam, H.1    Gielen, S.C.2    Kloosterboer, H.J.3
  • 37
    • 0037331924 scopus 로고    scopus 로고
    • Mechanisms involved in the evolution of progestin resistance in human endometrial hyperplasia-precursor of endometrial cancer
    • Wang S, Pudney J, Song J, Mor G, Schwartz PE, Zheng W. Mechanisms involved in the evolution of progestin resistance in human endometrial hyperplasia-precursor of endometrial cancer. Gynecol Oncol 2003;88:108-17.
    • (2003) Gynecol Oncol , vol.88 , pp. 108-117
    • Wang, S.1    Pudney, J.2    Song, J.3    Mor, G.4    Schwartz, P.E.5    Zheng, W.6
  • 38
    • 0034784709 scopus 로고    scopus 로고
    • Effects of the levonorgestrel-releasing intrauterine system on proliferation and apoptosis in the endometrium
    • Maruo T, Laoag-Fernandez JB, Pakarinen P, Murakoshi H, Spitz IM, Johansson E. Effects of the levonorgestrel-releasing intrauterine system on proliferation and apoptosis in the endometrium. Hum Reprod 2001;16:2103-8.
    • (2001) Hum Reprod , vol.16 , pp. 2103-2108
    • Maruo, T.1    Laoag-Fernandez, J.B.2    Pakarinen, P.3    Murakoshi, H.4    Spitz, I.M.5    Johansson, E.6
  • 40
    • 0036063428 scopus 로고    scopus 로고
    • Regulation of human endometrial transforming growth factor β1 and β3 isoforms through menstrual cycle and medroxyprogesterone acetate treatment
    • Reis FM, Ribeiro MF, Maia AL, Spritzer PM. Regulation of human endometrial transforming growth factor β1 and β3 isoforms through menstrual cycle and medroxyprogesterone acetate treatment. Histol Histopathol 2002;17:739-45.
    • (2002) Histol Histopathol , vol.17 , pp. 739-745
    • Reis, F.M.1    Ribeiro, M.F.2    Maia, A.L.3    Spritzer, P.M.4
  • 41
    • 27944469591 scopus 로고    scopus 로고
    • Endometrial expression of immunomodulatory cytokines and their regulators during early pregnancy in bonnet monkeys (Macaca radiata)
    • Rosario GX, Sachdeva G, Manjramkar DD, Modi DN, Meherji PK, Puri CP. Endometrial expression of immunomodulatory cytokines and their regulators during early pregnancy in bonnet monkeys (Macaca radiata). Hum Reprod 2005;20:3039-46.
    • (2005) Hum Reprod , vol.20 , pp. 3039-3046
    • Rosario, G.X.1    Sachdeva, G.2    Manjramkar, D.D.3    Modi, D.N.4    Meherji, P.K.5    Puri, C.P.6
  • 42
    • 0029850643 scopus 로고    scopus 로고
    • Analysis of differential gene regulation in adequate versus inadequate secretory-phase endometrial complementary deoxyribonucleic acid populations from the rhesus monkey
    • Okulicz WC, Ace CI, Longcope C, Tast J. Analysis of differential gene regulation in adequate versus inadequate secretory-phase endometrial complementary deoxyribonucleic acid populations from the rhesus monkey. Endocrinology 1996;137:4844-50.
    • (1996) Endocrinology , vol.137 , pp. 4844-4850
    • Okulicz, W.C.1    Ace, C.I.2    Longcope, C.3    Tast, J.4
  • 43
    • 0028820619 scopus 로고
    • Differential gene regulation by estrogen and progesterone in the primate endometrium
    • Ace CI, Okulicz WC. Differential gene regulation by estrogen and progesterone in the primate endometrium. Mol Cell Endocrinol 1995;115:95-103.
    • (1995) Mol Cell Endocrinol , vol.115 , pp. 95-103
    • Ace, C.I.1    Okulicz, W.C.2
  • 44
    • 0344507146 scopus 로고    scopus 로고
    • Three distinct roles for TGF-β during intercellular induction of apoptosis: A review
    • Haufel T, Dormann S, Hanusch J, Schwieger A, Bauer G. Three distinct roles for TGF-β during intercellular induction of apoptosis: a review. Anticancer Res 1999;19:105-12.
    • (1999) Anticancer Res , vol.19 , pp. 105-112
    • Haufel, T.1    Dormann, S.2    Hanusch, J.3    Schwieger, A.4    Bauer, G.5
  • 45
    • 0027462443 scopus 로고
    • Transforming growth factor-β1 as a signal for induction of cell death by apoptosis
    • Bursch W, Oberhammer F, Jirtle RL, et al. Transforming growth factor-β1 as a signal for induction of cell death by apoptosis. Br J Cancer 1993;67:531-6.
    • (1993) Br J Cancer , vol.67 , pp. 531-536
    • Bursch, W.1    Oberhammer, F.2    Jirtle, R.L.3
  • 46
    • 0031126857 scopus 로고    scopus 로고
    • Complex interplay among apoptosis factors: RB, p53, E2F, TGF-β, cell cycle inhibitors and the bcl2 gene family
    • Chiarugi V, Magnelli L, Cinelli M. Complex interplay among apoptosis factors: RB, p53, E2F, TGF-β, cell cycle inhibitors and the bcl2 gene family. Pharmacol Res 1997;35:257-61.
    • (1997) Pharmacol Res , vol.35 , pp. 257-261
    • Chiarugi, V.1    Magnelli, L.2    Cinelli, M.3
  • 47
    • 0026546918 scopus 로고
    • Regulation of growth of normal ovarian epithelial cells and ovarian cancer cell lines by transforming growth factor-β
    • Berchuck A, Rodriguez G, Olt GJ, et al. Regulation of growth of normal ovarian epithelial cells and ovarian cancer cell lines by transforming growth factor-β. Am J Obstet Gynecol 1992;166:676-84.
    • (1992) Am J Obstet Gynecol , vol.166 , pp. 676-684
    • Berchuck, A.1    Rodriguez, G.2    Olt, G.J.3
  • 48
    • 0028304722 scopus 로고
    • Transforming growth factor-β inhibits proliferation of human ovarian cancer cells obtained from ascites
    • Hurteau J, Rodriguez GC, Whitaker RS, et al. Transforming growth factor-β inhibits proliferation of human ovarian cancer cells obtained from ascites. Cancer 1994;74:93-9.
    • (1994) Cancer , vol.74 , pp. 93-99
    • Hurteau, J.1    Rodriguez, G.C.2    Whitaker, R.S.3
  • 49
    • 0028815882 scopus 로고
    • Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor β
    • Havrilesky LJ, Hurteau JA, Whitaker RS, et al. Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor β. Cancer Res 1995;55:944-8.
    • (1995) Cancer Res , vol.55 , pp. 944-948
    • Havrilesky, L.J.1    Hurteau, J.A.2    Whitaker, R.S.3
  • 50
    • 0026318253 scopus 로고
    • Coordinated regulation of apoptosis and cell proliferation by transforming growth factor 1 in cultured uterine epithelial cells
    • Rotello RJ, Lieberman RC, Purchio AF, Gershenson LE. Coordinated regulation of apoptosis and cell proliferation by transforming growth factor 1 in cultured uterine epithelial cells. Proc Natl Acad Sci US A 1991;88:3412-5.
    • (1991) Proc Natl Acad Sci US A , vol.88 , pp. 3412-3415
    • Rotello, R.J.1    Lieberman, R.C.2    Purchio, A.F.3    Gershenson, L.E.4
  • 51
    • 0031743456 scopus 로고    scopus 로고
    • Additive effect of mifepristone and tamoxifen on apoptotic pathways in MCF-7 human breast cancer cells
    • El Etreby MF, Liang Y, Wrenn RW, Schoenlein PV. Additive effect of mifepristone and tamoxifen on apoptotic pathways in MCF-7 human breast cancer cells. Breast Cancer Res Treat 1998;51:149-68.
    • (1998) Breast Cancer Res Treat , vol.51 , pp. 149-168
    • El Etreby, M.F.1    Liang, Y.2    Wrenn, R.W.3    Schoenlein, P.V.4
  • 52
    • 0030199843 scopus 로고    scopus 로고
    • Effects of 1,25 dihydroxyvitamin D3 and its analogues on induction of apoptosis in breast cancer cells
    • James SY, Mackay AG, Colston KW. Effects of 1,25 dihydroxyvitamin D3 and its analogues on induction of apoptosis in breast cancer cells. J Steroid Biochem Mol Biol 1996;58:395-401.
    • (1996) J Steroid Biochem Mol Biol , vol.58 , pp. 395-401
    • James, S.Y.1    Mackay, A.G.2    Colston, K.W.3
  • 53
    • 0024421852 scopus 로고
    • Expression of transforming growth factor-β in the rat ventral prostate during castration-induced programmed cell death
    • Kyprianou N, Isaacs JT. Expression of transforming growth factor-β in the rat ventral prostate during castration-induced programmed cell death. Mol Endocrinol 1989;3:1515-22.
    • (1989) Mol Endocrinol , vol.3 , pp. 1515-1522
    • Kyprianou, N.1    Isaacs, J.T.2
  • 54
    • 0031031450 scopus 로고    scopus 로고
    • Fenretinide: Induction of apoptosis and endogenous transforming growth factor-β in PC-3 prostate cancer cells
    • Roberson KM, Penland SN, Padilla GM, et al. Fenretinide: induction of apoptosis and endogenous transforming growth factor-β in PC-3 prostate cancer cells. Cell Growth Differ 1997;8:101-11.
    • (1997) Cell Growth Differ , vol.8 , pp. 101-111
    • Roberson, K.M.1    Penland, S.N.2    Padilla, G.M.3
  • 55
    • 2442688166 scopus 로고    scopus 로고
    • The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor β-dependent apoptosis in breast cancer
    • Rendi MH, Suh N, Lamph WW, et al. The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor β-dependent apoptosis in breast cancer. Cancer Res 2004;64:3566-71.
    • (2004) Cancer Res , vol.64 , pp. 3566-3571
    • Rendi, M.H.1    Suh, N.2    Lamph, W.W.3
  • 56
    • 85047678410 scopus 로고    scopus 로고
    • High specificity of Müllerian-inhibiting substance signaling in vivo
    • Mishina Y, Whitworth DJ, Racine C, Behringer RR. High specificity of Müllerian-inhibiting substance signaling in vivo. Endocrinology 1999;140:2084-8.
    • (1999) Endocrinology , vol.140 , pp. 2084-2088
    • Mishina, Y.1    Whitworth, D.J.2    Racine, C.3    Behringer, R.R.4
  • 57
    • 0024512162 scopus 로고
    • Potential relevance of Mullerian-inhibiting substance to ovarian physiology
    • Voutilainen R, Miller WL. Potential relevance of Mullerian-inhibiting substance to ovarian physiology. Semin Reprod Endocrinol 1989;7:88-93.
    • (1989) Semin Reprod Endocrinol , vol.7 , pp. 88-93
    • Voutilainen, R.1    Miller, W.L.2
  • 58
    • 0022499726 scopus 로고
    • Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells
    • Cate RL, Mattaliano RJ, Hession C, et al. Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells. Cell 1986;45:685-98.
    • (1986) Cell , vol.45 , pp. 685-698
    • Cate, R.L.1    Mattaliano, R.J.2    Hession, C.3
  • 59
    • 0022919252 scopus 로고
    • Differentiation of mammalian embryonic gonad
    • Byskov AG. Differentiation of mammalian embryonic gonad. Physiol Rev 1986;66:71-117.
    • (1986) Physiol Rev , vol.66 , pp. 71-117
    • Byskov, A.G.1
  • 60
    • 0032753468 scopus 로고    scopus 로고
    • Human ovarian cancer, cell lines, and primary ascites cells express the human Mullerian inhibiting substance (MIS) type II receptor, bind, and are responsive to MIS
    • Masiakos PT, MacLaughlin DT, Maheswaran S, et al. Human ovarian cancer, cell lines, and primary ascites cells express the human Mullerian inhibiting substance (MIS) type II receptor, bind, and are responsive to MIS. Clin Cancer Res 1999;11:3488-99.
    • (1999) Clin Cancer Res , vol.11 , pp. 3488-3499
    • Masiakos, P.T.1    MacLaughlin, D.T.2    Maheswaran, S.3
  • 64
    • 0031303927 scopus 로고    scopus 로고
    • Transforming growth factor-β and cancer: A love-hate relationship?
    • Reiss M. Transforming growth factor-β and cancer: a love-hate relationship? Oncol Res 1997;9:447-57.
    • (1997) Oncol Res , vol.9 , pp. 447-457
    • Reiss, M.1
  • 65
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor in human disease
    • Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor in human disease. N Engl J Med 2000;342:1350-8.
    • (2000) N Engl J Med , vol.342 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 66
    • 33044503641 scopus 로고    scopus 로고
    • Transforming growth factor β signaling in cancer
    • Narayan S, Thangasamy T, Balusu R. Transforming growth factor β signaling in cancer. Front Biosci 2005;10:1135-45.
    • (2005) Front Biosci , vol.10 , pp. 1135-1145
    • Narayan, S.1    Thangasamy, T.2    Balusu, R.3
  • 67
    • 0029010734 scopus 로고
    • Mammary tumor suppression by transforming growth factor β1 transgene expression
    • Pierce DF Jr, Gorska AE, Chytil A, et al. Mammary tumor suppression by transforming growth factor β1 transgene expression. Proc Natl Acad Sci US A 1995;92:4254-8.
    • (1995) Proc Natl Acad Sci US A , vol.92 , pp. 4254-4258
    • Pierce Jr, D.F.1    Gorska, A.E.2    Chytil, A.3
  • 68
    • 0007999460 scopus 로고    scopus 로고
    • Enhanced liver and lung tumorigenesis in TGF-β1 heterozygous knock-out mice following treatment with diethylnitrosamine and phenobarbital [abstract]
    • Tang B, Bottiner E, Bagnall K, Anver M, Wakefield L. Enhanced liver and lung tumorigenesis in TGF-β1 heterozygous knock-out mice following treatment with diethylnitrosamine and phenobarbital [abstract]. Proc Am Assoc Cancer Res 1997;38:584.
    • (1997) Proc Am Assoc Cancer Res , vol.38 , pp. 584
    • Tang, B.1    Bottiner, E.2    Bagnall, K.3    Anver, M.4    Wakefield, L.5
  • 69
    • 24644467718 scopus 로고    scopus 로고
    • Deregulated TGF-Beat signaling in leukemogenesis
    • Lin HK, Bergmann S, Pandolfi PP. Deregulated TGF-Beat signaling in leukemogenesis. Oncogene 2005;24:5693-700.
    • (2005) Oncogene , vol.24 , pp. 5693-5700
    • Lin, H.K.1    Bergmann, S.2    Pandolfi, P.P.3
  • 70
    • 33748531817 scopus 로고    scopus 로고
    • Ubiquitin-dependent regulation of TGF-β signalling in cancer
    • Izzi L, Attisano L. Ubiquitin-dependent regulation of TGF-β signalling in cancer. Neoplasia 2006;8:677-88.
    • (2006) Neoplasia , vol.8 , pp. 677-688
    • Izzi, L.1    Attisano, L.2
  • 71
    • 15744372725 scopus 로고    scopus 로고
    • Role of Transforming Growth Factor β in human cancer
    • Elliot RL, Blobe GC. Role of Transforming Growth Factor β in human cancer. J Clin Oncol 2005;23:2078-93.
    • (2005) J Clin Oncol , vol.23 , pp. 2078-2093
    • Elliot, R.L.1    Blobe, G.C.2
  • 72
    • 4444226148 scopus 로고    scopus 로고
    • Role of TGF-β in cancer and the potential for therapy and prevention
    • Kaklamani VG, Pasche B. Role of TGF-β in cancer and the potential for therapy and prevention. Expert Rev Anticancer Ther 2004;4:649-61.
    • (2004) Expert Rev Anticancer Ther , vol.4 , pp. 649-661
    • Kaklamani, V.G.1    Pasche, B.2
  • 73
    • 21244479759 scopus 로고    scopus 로고
    • Fine tuning and cross-talking of TGF-β signal by inhibitory smads
    • Park SH. Fine tuning and cross-talking of TGF-β signal by inhibitory smads. J Biochem Mol Biol 2005;38:9-16.
    • (2005) J Biochem Mol Biol , vol.38 , pp. 9-16
    • Park, S.H.1
  • 74
    • 2442561553 scopus 로고    scopus 로고
    • Apoptosis as a novel target for cancer prevention
    • Sun SY, Hail N, Lotan R. Apoptosis as a novel target for cancer prevention. J Natl Cancer Inst 2004;96:662-72.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 662-672
    • Sun, S.Y.1    Hail, N.2    Lotan, R.3
  • 75
    • 31544463796 scopus 로고    scopus 로고
    • NO-donating aspirin isomers downregulate peroxisome proliferator-activated receptor (PPAR)δ expression in APC(min/+) mice proportionally to their tumor inhibitory effect: Implications for the role of PPARδ in carcinogenesis
    • Ouyang N, Williams JL, Rigas B. NO-donating aspirin isomers downregulate peroxisome proliferator-activated receptor (PPAR)δ expression in APC(min/+) mice proportionally to their tumor inhibitory effect: implications for the role of PPARδ in carcinogenesis. Carcinogenesis 2006;27:232-9.
    • (2006) Carcinogenesis , vol.27 , pp. 232-239
    • Ouyang, N.1    Williams, J.L.2    Rigas, B.3
  • 76
    • 2942627339 scopus 로고    scopus 로고
    • Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in familial adenomatous polyposis patients
    • Sinicrope FA, Half E, Morris JS, et al. Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in familial adenomatous polyposis patients. Cancer Epidemiol Biomarkers Prev 2004;13:920-7.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 920-927
    • Sinicrope, F.A.1    Half, E.2    Morris, J.S.3
  • 77
    • 0033026714 scopus 로고    scopus 로고
    • Mechanisms of apoptosis avoidance in cancer
    • Reed JC. Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999;11:68-75.
    • (1999) Curr Opin Oncol , vol.11 , pp. 68-75
    • Reed, J.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.