Metinel node - The first lymph node draining a metastasis - Contains tumor-reactive lymphocytes

Annals of Surgical Oncology

Volumn 15, Issue 5, 2008, Pages 1454-1463

  Dahl, Kjell ^a   Karlsson, Mona ^b   Marits, Per ^b   Hoffstedt, Anna ^a   Winqvist, Ola ^b   Thörn, Magnus ^a  

^a STOCKHOLM SÖDER HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Immunotherapy; Lymphatic mapping; Metastases; Sentinel node; Solid tumors

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; TECHNETIUM;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER SURGERY; CELLULAR IMMUNITY; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; LYMPH NODE; LYMPH NODE METASTASIS; LYMPHATIC DRAINAGE; LYMPHOSCINTIGRAPHY; MALE; MELANOMA; METINEL NODE; OVARY CANCER; PANCREAS CANCER; T LYMPHOCYTE; TONGUE CANCER;

ADULT; AGED; CELLS, CULTURED; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOTHERAPY; INTERFERON TYPE II; LIVER NEOPLASMS; LYMPH NODES; LYMPHATIC METASTASIS; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PREOPERATIVE CARE; PROGNOSIS; RADIOPHARMACEUTICALS; ROSANILINE DYES; TECHNETIUM TC 99M SULFUR COLLOID;

EID: 41549128459     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-007-9788-7     Document Type: Article

References (39)

1. Parkin DM, Bray F, Ferlay J, et al. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74-108
2. Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006;24:2137-50
3. Nathanson SD. Insights into the mechanisms of lymph node metastasis. Cancer 2003;98:413-23
4. Lyman GH, Giuliano AE, Somerfield MR, et al. American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer. J Clin Oncol 2005;23:7703-20
5. Thompson JF, Scolyer RA, Kefford RF. Cutaneous melanoma. Lancet 2005;365:687-701
6. Dahl K, Westlin J, Kraaz W, et al. Identification of sentinel nodes in patients with colon cancer. Eur J Surg Oncol 2005;31:381-5
7. Negishi H, Takeda M, Fujimoto T, et al. Lymphatic mapping and sentinel node identification as related to the primary sites of lymph node metastasis in early stage ovarian cancer. Gynecol Oncol 2004;94:161-6
8. Ohta T, Kitagawa H, Kayahara M, et al. Sentinel lymph node navigation surgery for pancreatic head cancers. Oncol Rep 2003;10:315-9
9. Sherif A, De La Torre M, Malmstrom PU, et al. Lymphatic mapping and detection of sentinel nodes in patients with bladder cancer. J Urol 2001;166:812-5
10. Sherif A, Garske U, De la Torre M, et al. Hybrid SPECT-CT: an additional technique for sentinel node detection of patients with invasive bladder cancer. Eur Urol 2006;50:83-91
11. Alitalo K, Mohla S, Ruoslahti E. Lymphangiogenesis and cancer: meeting report. Cancer Res 2004;64:9225-9
12. Padera TP, Kadambi A, di Tomaso E, et al. Lymphatic metastasis in the absence of functional intratumor lymphatics. Science 2002;296:1883-6
13. Poste G, Fidler IJ. The pathogenesis of cancer metastasis. Nature 1980;283:139-46
14. Kane JM 3rd, Kahlenberg MS, Rodriguez-Bigas MA, et al. Intraoperative hepatic lymphatic mapping in patients with liver metastases from colorectal carcinoma. Am Surg 2002;68:745-50
15. Hoover HC Jr, Ketcham AS. Metastasis of metastases. Am J Surg 1975;130:405-11
16. Ketcham AS, Ryan JJ, Wexler H. The shredding of viable circulating tumor cells by pulmonary metastases in mice. Ann Surg 1969;169:297-9
17. Weiss L, Holmes JC, Ward PM. Do metastases arise from pre-existing subpopulations of cancer cells? Br J Cancer 1983;47:81-9
18. Van den Eynden GG, Van der Auwera I, Van Laere SJ, et al. Induction of lymphangiogenesis in and around axillary lymph node metastases of patients with breast cancer. Br J Cancer 2006;95:1362-6
19. Marits P, Karlsson M, Dahl K, et al. Sentinel node lymphocytes: tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer. Br J Cancer 2006;94:1478-84
20. Marits P, Karlsson M, Sherif A, et al. Detection of immune responses against urinary bladder cancer in sentinel lymph nodes. Eur Urol 2006;49:59-70
21. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6
22. Weidner N, Semple JP, Welch WR, et al. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8
23. Baldwin ME, Stacker SA, Achen MG. Molecular control of lymphangiogenesis. Bioessays 2002;24:1030-40
24. Renkin EM. Some consequences of capillary permeability to macromolecules: Starling's hypothesis reconsidered. Am J Physiol 1986;250:H706-10
25. Kawakami M, Furuhata T, Kimura Y, et al. Quantification of vascular endothelial growth factor-C and its receptor-3 messenger RNA with real-time quantitative polymerase chain reaction as a predictor of lymph node metastasis in human colorectal cancer. Surgery 2003;133:300-8
26. White JD, Hewett PW, Kosuge D, et al. Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma. Cancer Res 2002;62:1669-75
27. Nakamura S, Yokoi Y, Suzuki S, et al. Results of extensive surgery for liver metastases in colorectal carcinoma. Br J Surg 1992;79:35-8
28. Rodgers MS, McCall JL. Surgery for colorectal liver metastases with hepatic lymph node involvement: a systematic review. Br J Surg 2000;87:1142-55
29. August DA, Sugarbaker PH, Schneider PD. Lymphatic dissemination of hepatic metastases. Implications for the follow-up and treatment of patients with colorectal cancer. Cancer 1985;55:1490-4
30. Standring S. Gray's Anatomy, 39th ed. London: Churchill Livingstone, Elsevier, 2005:1221-2
31. Grobmyer SR, Wang L, Gonen M, et al. Perihepatic lymph node assessment in patients undergoing partial hepatectomy for malignancy. Ann Surg 2006;244:260-4
32. Laurent C, Sa Cunha A, Rullier E, et al. Impact of microscopic hepatic lymph node involvement on survival after resection of colorectal liver metastasis. J Am Coll Surg 2004;198:884-91
33. Barrett T, Choyke PL, Kobayashi H. Imaging of the lymphatic system: new horizons. Contrast Media Mol Imaging 2006;1:230-45
34. Burnet FM. The concept of immunological surveillance. Prog Exp Tumor Res 1970;13:1-27
35. Pham SM, Kormos RL, Landreneau RJ, et al. Solid tumors after heart transplantation: lethality of lung cancer. Ann Thorac Surg 1995;60:1623-6
36. Thornton AD, Ravn P, Winslet M, et al. Angiogenesis inhibition with bevacizumab and the surgical management of colorectal cancer. Br J Surg 2006;93:1456-63
37. Pages F, Berger A, Camus M, et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med 2005;353:2654-66
38. Zhang L, Conejo-Garcia JR, Katsaros D, et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl J Med 2003;348:203-13
39. Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006;313:1960-4