Differential effects of fibrates on the metabolic activation of 2-phenylpropionic acid in rats

Drug Metabolism and Disposition

Volumn 36, Issue 4, 2008, Pages 682-687

  Li, Chunze ^a,b   Grillo, Mark P ^a,c   Badagnani, Ilaria ^a,d   Fife, Kimberly L ^a   Benet, Leslie Z ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PFIZER INC   (United States)

^c AMGEN INC   (United States)

^d ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; CLOFIBRIC ACID; DRUG METABOLITE; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; GLUCURONIDE; HYDRATROPIC ACID; LIVER PROTEIN; LONG CHAIN FATTY ACID COENZYME A LIGASE; THIOESTER;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DRUG EFFECT; DRUG LIVER LEVEL; DRUG METABOLISM; ENZYME ACTIVITY; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER HOMOGENATE; MALE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE;

ANIMALS; BIOTRANSFORMATION; CLOFIBRIC ACID; LIVER; MALE; PHENYLPROPIONATES; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 41549115474     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.017764     Document Type: Article

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