In vitro studies on the chemical reactivity of 2,4-dichlorophenoxyacetyl-S-acyl-CoA thioester

Toxicology and Applied Pharmacology

Volumn 187, Issue 2, 2003, Pages 101-109

  Li, Chunze ^a   Grillo, Mark P ^b   Benet, Leslie Z ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PFIZER INC   (United States)

Author keywords

2,4 D; 2,4 Dichlorophenoxyacetic acid; Acyl CoA; Covalent binding; Reactive metabolite

Indexed keywords

2,4 DICHLOROPHENOXYACETIC ACID; 2,4 DICHLOROPHENOXYACETYL S ACYL COENZYME A THIOSTER; 2,4 DICHLOROPHENOXYACETYL S ACYLGLUTATHIONE THIOESTER; ACYL COENZYME A; CARBON 14; CYSTEINE DERIVATIVE; GLUTATHIONE; HUMAN SERUM ALBUMIN; PHENOXYACETIC ACID DERIVATIVE; PHOSPHATE; PIVALIC ACID; THIOL DERIVATIVE; THIOXYL DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL BINDING; CHEMICAL REACTION; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; DISEASE ASSOCIATION; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER TOXICITY; MALE; METABOLITE; NONHUMAN; PROTEIN BINDING; RAT; TIME;

ANIMALIA;

EID: 0344837751     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(02)00043-1     Document Type: Article

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