Green chemistry metrics: A comparative evaluation of dimethyl carbonate, methyl iodide, dimethyl sulfate and methanol as methylating agents

Green Chemistry

Volumn 10, Issue 4, 2008, Pages 457-46

  Selva, Maurizio ^a   Perosa, Alvise ^a  

^a CA' FOSCARI UNIVERSITY OF VENICE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 41549109336     PISSN: 14639262     EISSN: 14639270     Source Type: Journal    
DOI: 10.1039/b713985c     Document Type: Article

References (92)

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92. The formation of the toxic methanol as a co-product of DMC-mediated methylations (Scheme 3, 4 and 6), might somewhat mitigate the environmental benefits of DMC. Methanol is usually isolated (and disposed) by filtration/distillation, under conditions which are more controlled (and safer) than those used for the reactions. A thorough assessment of this problem should however, be carried out by toxicological metrics, not pertinent to this work.